Artículo

Estamos trabajando para incorporar este artículo al repositorio
Consulte el artículo en la página del editor
Consulte la política de Acceso Abierto del editor

Abstract:

Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered. © 2008 Future Medicine Ltd.

Registro:

Documento: Artículo
Título:Cell entry of dengue virus
Autor:Acosta, E.G.; Talarico, L.B.; Damonte, E.B.
Filiación:Laboratorio de Virología, Departamento de Química Biológica, Universidad de Buenos Aires, Pabellón 2, Piso 4, 1428 Buenos Aires, Argentina
Palabras clave:Antiviral therapy; Dengue virus; Envelope E glycoprotein; Flavivirus; Receptor; Virus attachment; Virus entry; amantadine; CD14 antigen; chlorpromazine; concanavalin A; galactan; glucan; glucose regulated protein 78; glycoprotein E1; heat shock protein 70; heat shock protein 90; heparin; laminin receptor; lectin; mannose receptor; pentosan polysulfate; pi 88; polyanion; rimantadine; suramin; synthetic peptide; tetracycline derivative; tubulin; virus receptor; antiviral activity; dengue; Dengue virus; host range; human; life cycle; nonhuman; priority journal; protein function; protein targeting; review; virion; virus attachment; virus entry; virus replication; Aedes aegypti; Dengue virus; Flavivirus; Mammalia
Año:2008
Volumen:3
Número:5
Página de inicio:471
Página de fin:479
DOI: http://dx.doi.org/10.2217/17460794.3.5.471
Título revista:Future Virology
Título revista abreviado:Future Virol.
ISSN:17460794
CAS:amantadine, 665-66-7, 768-94-5; chlorpromazine, 50-53-3, 69-09-0; concanavalin A, 11028-71-0; galactan, 39300-87-3, 9037-55-2; glucan, 9012-72-0, 9037-91-6; heparin, 37187-54-5, 8057-48-5, 8065-01-8, 9005-48-5; pentosan polysulfate, 116001-96-8, 37300-21-3, 37319-17-8; rimantadine, 13392-28-4, 1501-84-4; suramin, 129-46-4, 145-63-1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_17460794_v3_n5_p471_Acosta

Referencias:

  • Gubler, D.J., Dengue and dengue hemorrhagic fever (1998) Clin. Microbiol. Rev, 11, pp. 480-496
  • Kliks, S.C., Nisalak, A., Brandt, W.E., Wahl, L., Burke, D.S., Antibody-dependent enhancement of dengue virus growth in human monocytes as a risk factor for dengue hemorrhagic fever (1989) Am. J. Trop. Med. Hyg, 40, pp. 444-451
  • Rothman, A.L., Dengue: Defining protective versus pathologic immunity (2004) J. Clin. Inv, 113, pp. 946-951
  • Gubler, D.J., Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century (2002) Trends Microbiol, 10, pp. 100-103
  • Salas-Benito, J.S., del Angel, R.M., Identification of two surface proteins from C6/36 cells that bind dengue type 4 virus (1997) J. Virol, 71, pp. 7246-7252
  • Salas-Benito, J., Reyes-Del Valle, J., Salas-Benito, M., Ceballos-Olvera, I., Mosso, C., del Angel, R.M., Evidence that the 45-kD glycoprotein, part of a putative dengue virus receptor complex in the mosquito cell line C6/36, is a heat-shock related protein (2007) Am. J. Trop. Med. Hyg, 77, pp. 283-290
  • Muñoz, M.L., Cisneros, A., Cruz, J., Das, P., Tovar, R., Ortega, A., Putative dengue virus receptors from mosquito cells (1998) FEMS Microbiol. Lett, 168, pp. 251-258
  • Chee, H.-Y., AbuBakar, S., Identification of a 48 kDa tubulin or tubulin-like C6/36 mosquito cells protein that binds dengue virus 2 using mass spectrometry (2004) Biochem. Biophys. Res. Commun, 320, pp. 11-17
  • Sakoonwatanyoo, P., Boonsanay, V., Smith, D.R., Growth and production of the dengue virus in C6/36 cells and identification of a laminin-binding protein as a candidate serotype 3 and 4 receptor protein (2006) Inter Virology, 49, pp. 161-172
  • Reyes-Del Valle, J., Chavez-Salinas, S., Medina, F., Del Angel, R.M., Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells (2005) J Virol, 79, pp. 4557-4567
  • Jindadamrongwech, S., Thepparit, C., Smith, D.R., Identification of GRP 78 (BiP) as a liver cell expressed receptor element for dengue virus serotype 2 (2004) Arch. Virol, 149, pp. 915-927
  • Thepparit, C., Smith, D.R., Serotype-specific entry of dengue virus into liver cells: Identification of the 37-kilodalton/67-kilodalton high-affinity laminin receptor as a dengue virus serotype 1 receptor (2004) J. Virol, 78, pp. 12647-12656
  • Miller, J.L., Dewet, B.J., Martinez-Pomares, L., The mannose receptor mediates dengue virus infection of macrophages (2008) PLoS Pathog, 4, pp. e17
  • Chen, Y., Maguire, T., Marks, R.M., Demonstration of binding of dengue virus envelope protein to target cells (1996) J. Virol, 70, pp. 8765-8772
  • Chen, Y.C., Wang, S.Y., King, C.C., Bacterial lipopolysaccharide inhibits dengue virus infection of primary human monocytes/macrophages by blockade of virus entry via a cD14-dependent mechanism (1999) J. Virol, 73, pp. 2650-2657
  • Navarro-Sanchez, E., Altmeyer, R., Amara, A., Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses (2003) EMBO Rep, , 4, 723-728
  • Tassaneetrithep, B., Burgess, T.H., Granelli-Piperno, A., DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells (2003) J. Exp. Med, 197, pp. 823-829
  • Marianneau, P., Mégret, F., Olivier, R., Morens, D.M., Deubel, V., Dengue 1 virus binding to human hepatoma HepG2 and simian Vero cell surfaces differs (1996) J. Gen. Virol, 77, pp. 2547-2554
  • Rothwell, S.W., Putnak, R., La Russa, V.F., Dengue-2 virus infection of human bone marrow: Characterization of dengue-2 antigen-positive stromal cells (1996) Am. J. Trop. Med. Hyg, 54, pp. 503-510
  • Ramos-Castañeda, J., Imbert, J.L., Barron, B.L., Ramos, C., A 65-kDa trypsin sensible membrane cell protein as a posible receptor for dengue virus in cultured neuroblastoma cells (1997) J Neurovirol, 3, pp. 435-440
  • Bielefeldt-Ohmann, H., Analysis of antibody-independent binding of dengue viruses and dengue virus envelope protein to human myelomonocytic cells and B lymphocytes (1998) Virus Res, 57, pp. 63-79
  • Bielefeldt-Ohmann, H., Meyer, M., Fitzpatrick, D.R., Mackenzie, J.S., Dengue virus binding to human leukocyte cell lines: Receptor usage differs between cell types and virus strains (2001) Virus Res, 73, pp. 81-89
  • Martínez-Barragán, J.J., del Angel, R.M., Identification of a putative coreceptor on Vero cells that participates in dengue 4 virus infection (2001) J. Virol, 75, pp. 7818-7827
  • Moreno-Altamirano, M.M.B., Sánchez-García, F.J., Mu-tinoz, M.L., Non Fc receptor-mediated infection of human macrophages by dengue virus serotype 2 (2002) J. Gen. Virol, 83, pp. 1123-1130
  • Wei, H.Y., Jiang, L.F., Fang, D.Y., Guo, H.Y., Dengue virus type 2 infects human endothelial cells through binding of the viral envelope glycoprotein to cell surface polypeptides (2003) J. Gen. Virol, 84, pp. 3095-3098
  • Chen, Y., Maguire, T., Hileman, R.E., Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate (1997) Nat. Med, 3, pp. 866-871
  • Hung, S.L., Lee, P.L., Chen, H.W., Chen, L.K., Kao, C.L., King, C.C., Analysis of the steps involved in dengue virus entry into host cells (1999) Virology, 257, pp. 156-167
  • Hilgard, P., Stockert, R., Heparan sulfate proteoglycans initiate dengue virus infection of hepatocytes (2000) Hepatology, 32, pp. 1069-1077
  • Germi, R., Crance, J.M., Garin, D., Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus (2002) Virology, 292, pp. 162-168
  • Spillmann, D., Heparan sulfate: Anchor for viral intruders (2001) Biochimie, 83, pp. 811-817
  • Lin, Y.L., Lei, H.Y., Lin, Y.S., Yeh, T.M., Chen, S.H., Liu, H.S., Heparin inhibits dengue-2 virus infection of five human liver cell lines (2002) Antiviral Res, 56, pp. 93-96
  • Talarico, L.B., Pujol, C.A., Zibetti, R.G.M., The antiviral activity of sulfated polysaccharides against dengue virus is dependent on virus serotype and host cell (2005) Antiviral Res, 66, pp. 103-110
  • Lozach, P.Y., Burleigh, L., Staropoli, I., Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals (2005) J. Biol. Chem, 280, pp. 23698-23708
  • Pelkmans, L., Secrets of caveolae- and lipid raft-mediated endocytosis revealed by mammalian viruses (2005) Biochim. Biophys. Acta, 1749, pp. 295-304
  • Kirkham, M., Parton, R.G., Clathrin-independent endocytosis: New insights into caveolae and non-caveolar lipid raft carriers (2005) Biochim. Biophys. Acta, 1745, pp. 273-286
  • Sieczkarski, S.B., Whittaker, G.R., Influenza virus can enter and infect cells in the absence of clathrin-mediated endocytosis (2005) J. Virol, 76, pp. 10455-10464
  • Marsh, M., Helenius, A., Virus entry: Open sesame (2006) Cell, 124, pp. 729-740
  • Hase, T., Summers, P.L., Eckels, K.H., Flavivirus entry into cultured mosquito cells and human peripheral blood monocytes (1989) Arch. Virol, 104, pp. 129-143
  • Lim, H.Y., Ng, M.L., A different mode of entry by dengue-2 neutralization escape mutant virus (1999) Arch. Virol, 144, pp. 989-995
  • Krishnan, M.N., Sukumaran, B., Pal, U., Rab 5 is required for the cellular entry of dengue virus and West Nile viruses (2007) J. Virol, 81, pp. 4881-4885
  • Acosta, E.G., Castilla, V., Damonte, E.B., Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis (2008) J. Gen. Virol, 89, pp. 474-484
  • Hu, H.-P., Hsieh, S.C., King, C.-C., Wang, W.-K., Characterization of retrovirus-based reporter viruses pseudotyped with the precursor membrane and envelope glycoproteins of four serotypes of dengue viruses (2007) Virology, 368, pp. 376-387
  • Randolph, V.B., Stollar, V., Law pH-induced cell fusion in flavivirus-infected Aedes albopictus cell cultures (1990) J. Gen. Virol, 71, pp. 1845-1850
  • van der Schaar, H.M., Rust, M.J., Waarts, B.-L., Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking (2007) J. Virol, 81, pp. 12019-12028
  • Modis, Y., Ogata, S., Clements, D., Harrison, S.C., Structure of the dengue virus envelope protein after membrane fusion (2004) Nature, 427, pp. 313-319
  • Zhang, Y., Zhang, W., Ogata, S., Conformational changes of the flavivirus E glycoprotein (2004) Structure, 12, pp. 1607-1618
  • Mukhopadhyay, S., Kuhn, R.J., Rossmann, M.G., A structural perspective of the flavivirus life cycle (2005) Nat. Rev. Microbiol, 3, pp. 13-22
  • Stiasny, K., Heinz, F.X., Flavivirus membrane fusion (2006) J. Gen. Virol, 87, pp. 2755-2766
  • Lee, C.-J., Lin, H.-R., Liao, C.-L., Lin, Y.-L., Cholesterol effectively blocks entry of flavivirus infection (2008) J. Virol, 82, pp. 6470-6480
  • Altmeyer, R., Virus attachment and entry offer numerous targets for antiviral therapy (2004) Curr. Pharm. Des, 10, pp. 3701-3712
  • Thaisomboonsuk, B.K., Clayson, E.T., Pantuwatana, S., Vaughn, D.W., Endy, T.P., Characterization of dengue-2 virus binding to surfaces of mammalian and insect cells (2005) Am. J. Trop. Med. Hyg, 72, pp. 375-383
  • Marks, R.M., Lu, H., Sundaresan, R., Probing the interaction of dengue virus envelope protein with heparin: Assessment of glycosaminoglycan-derived inhibitors (2001) J. Med. Chem, 44, pp. 2178-2187
  • Lee, E., Pavy, M., Young, N., Freeman, C., Lobigs, M., Antiviral effect of the heparan sulfate mimetic, PI-88, against dengue and encephalitic flaviviruses (2006) Antiviral Res, 69, pp. 31-38
  • Pujol, C.A., Estévez, J.M., Carlucci, M.J., Ciancia, M., Cerezo, A.S., Damonte, E.B., Novel DL-galactan hybrids from the red seaweed Gymnogongrus torulosus are potent inhibitors of herpes simplex virus and dengue virus (2002) Antivir. Chem. Chemother, 13, pp. 83-89
  • Talarico, L.B., Duarte, M.E.R., Zibetti, R.G.M., Noseda, M.D., Damonte, E.B., An algal derived DL-galactan hybrid is an efficient preventing agent for in vitro dengue virus infection (2007) Planta Med, 73, pp. 1464-1468
  • Qiu, H., Tang, W., Tong, X., Ding, K., Zuo, J., Structure elucidation and sulfated derivatives preparation of two α-D-glucans from Gastrodia elata B1 and their anti-dengue virus bioactivities (2007) Carbohydr. Res, 342, pp. 2230-2236
  • Rodríguez, M.C., Merino, E.R., Pujol, C.A., Damonte, E.B., Cerezo, A.S., Matulewicz, M.C., Galactans from cystocarpic plants of the red seaweed Callophyllic variegata (Kallymeniaceae, Gigartinales) (2005) Carbohydr. Res, 340, pp. 2742-2751
  • Tischer, P.C.S.F., Talarico, L.B., Noseda, M.D., Guimarees, S.M.P.B., Damonte, E.B., Duarte, M.E.R., Chemical structure and antiviral activity of carrageenans from Meristiella gelidium against herpes simplex and dengue virus (2006) Carbohydr. Polym, 63, pp. 459-465
  • Talarico, L.B., Damonte, E.B., Interference in dengue virus adsorption and uncoating by carrageenans (2007) Virology, 363, pp. 473-485
  • Ono, L., Wollinger, W., Rocco, I.M., Coimbra, T.L.M., Gorin, P.A.J., Sierakowski, M.R., In vitro and in vivo antiviral properties of sulfated galactomannans against yellow fever virus (BeH111 strain) and dengue 1 virus (Hawaii strain) (2003) Antiviral Res, 60, pp. 201-208
  • Shigeta, S., Mori, S., Kodama, E., Kodama, J., Takahashi, K., Yamase, T., Broad-spectrum anti-RNA virus activities of titanium and vanadium substituted polyoxotungstates (2003) Antiviral Res, 58, pp. 265-271
  • Damonte, E.B., Pujol, C.A., Coto, C.E., Prospects for the therapy and prevention of dengue virus infections (2004) Adv. Virus Res, 63, pp. 239-285
  • Koff, W.C., Elm Jr, J.L., Halstead, S.B., Inhibition of dengue virus replication by amantadine hydrochloride (1980) Antimicrob. Agents Chemother, 18, pp. 125-129
  • Koff, W.C., Elm Jr, J.L., Halstead, S.B., Suppression of dengue virus replication in vitro by rimantadine hydrochloride (1981) Am. J. Trop. Med. Hyg, 30, pp. 184-189
  • Nawa, M., Takasaki, T., Yamada, K., Kurane, I., Akatsuka, T., Interference in Japanese encephalitis virus infection of Vero cells by a cationic amphiphilic drug, chlorpromazine (2003) J. Gen. Virol, 84, pp. 1737-1741
  • Kuhn, R.J., Zhang, W., Rossmann, M.G., Structure of dengue virus: Implications for flavivirus organization, maturation, and fusion (2002) Cell, 108, pp. 717-725
  • Modis, Y., Ogata, S., Clements, D., Harrison, S.C., A ligand-binding pocket in the dengue virus envelope glycoprotein (2003) Proc. Natl Acad. Sci. USA, 100, pp. 6986-6991
  • Modis, Y., Ogata, S., Clements, D., Harrison, S.C., Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein (2005) J. Virol, 79, pp. 1223-1231
  • Volk, D.E., Lee, Y.-C., Li, X., Solution structure of the envelope protein domain III of dengue-4 virus (2007) Virology, 364, pp. 147-154
  • Hrobowski, Y.M., Garry, R.F., Michael, S.F., Peptide inhibitors of dengue virus and West Nile virus infectivity (2005) Virol. J, 2, p. 49
  • Yang, J.-M., Chen, Y.-F., Tu, Y.-Y., Yen, K.-R., Yang, Y.-L., Combinatorial computational approaches to identity tetracycline derivatives as flavivirus inhibitors (2007) PLoS One, 2, pp. e428

Citas:

---------- APA ----------
Acosta, E.G., Talarico, L.B. & Damonte, E.B. (2008) . Cell entry of dengue virus. Future Virology, 3(5), 471-479.
http://dx.doi.org/10.2217/17460794.3.5.471
---------- CHICAGO ----------
Acosta, E.G., Talarico, L.B., Damonte, E.B. "Cell entry of dengue virus" . Future Virology 3, no. 5 (2008) : 471-479.
http://dx.doi.org/10.2217/17460794.3.5.471
---------- MLA ----------
Acosta, E.G., Talarico, L.B., Damonte, E.B. "Cell entry of dengue virus" . Future Virology, vol. 3, no. 5, 2008, pp. 471-479.
http://dx.doi.org/10.2217/17460794.3.5.471
---------- VANCOUVER ----------
Acosta, E.G., Talarico, L.B., Damonte, E.B. Cell entry of dengue virus. Future Virol. 2008;3(5):471-479.
http://dx.doi.org/10.2217/17460794.3.5.471