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Ruiz, I.; Hermida, É.B.; Baldessari, A. "Fabrication and characterization of porous PHBV scaffolds for tissue engineering" (2011) 8th Argentinean Bioengineering Society Conference, SABI 2011 and 7th Clinical Engineering Meeting. 332(1)
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Abstract:

Porous scaffolds of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) were elaborated by three different techniques: salt leaching (SL), emulsion solvent evaporation (ESE) and temperature induced phase separation (TIPS). For SL partially fused sieved grains of sodium chloride (106-355 μm) were used as porogen. Emulsions, prepared from a solution of PHBV in chloroform allow getting flexible films; the content of surfactant may be used to control the pore size. The pore size of the TIPS scaffolds decreased on increasing the cooling rate and the morphology of the interconnected structure could be controlled by changing the temperature gradient. Finally, chemical changes associated to the enhancement of hydrophilic behaviour of the scaffolds after alkaline and enzymatic hydrolysis as well as after sterilization by γ irradiation are presented.

Registro:

Documento: Conferencia
Título:Fabrication and characterization of porous PHBV scaffolds for tissue engineering
Autor:Ruiz, I.; Hermida, É.B.; Baldessari, A.
Ciudad:Mar del Plata
Filiación:Instituto de Tecnología Prof. Jorge A. Sabato, UNSAM-CNEA, Av. Gral. Paz 1499, B1650KNA San Martín, Buenos Aires, Argentina
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Av. Rivadavia 1719, C1033AAJ Caba, Argentina
Laboratorio de Biocatálisis, Departamento de Química Orgánica, UBA, Intendente Güiraldes 2160, C1428EGA Caba, Argentina
Palabras clave:Alkalinity; Biomedical engineering; Emulsification; Enzymatic hydrolysis; Irradiation; Phase separation; Pore size; Tissue engineering; Emulsion solvent evaporation; Fabrication and characterizations; Gamma irradiation; Interconnected structures; Poly(3-hydroxybutyrate-co-3-hydroxyvalerate); Scaffolds for tissue engineering; Temperature-induced phase separation; Three different techniques; Scaffolds (biology)
Año:2011
Volumen:332
Número:1
DOI: http://dx.doi.org/10.1088/1742-6596/332/1/012028
Título revista:8th Argentinean Bioengineering Society Conference, SABI 2011 and 7th Clinical Engineering Meeting
Título revista abreviado:J. Phys. Conf. Ser.
ISSN:17426588
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_17426588_v332_n1_p_Ruiz

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Citas:

---------- APA ----------
Ruiz, I., Hermida, É.B. & Baldessari, A. (2011) . Fabrication and characterization of porous PHBV scaffolds for tissue engineering. 8th Argentinean Bioengineering Society Conference, SABI 2011 and 7th Clinical Engineering Meeting, 332(1).
http://dx.doi.org/10.1088/1742-6596/332/1/012028
---------- CHICAGO ----------
Ruiz, I., Hermida, É.B., Baldessari, A. "Fabrication and characterization of porous PHBV scaffolds for tissue engineering" . 8th Argentinean Bioengineering Society Conference, SABI 2011 and 7th Clinical Engineering Meeting 332, no. 1 (2011).
http://dx.doi.org/10.1088/1742-6596/332/1/012028
---------- MLA ----------
Ruiz, I., Hermida, É.B., Baldessari, A. "Fabrication and characterization of porous PHBV scaffolds for tissue engineering" . 8th Argentinean Bioengineering Society Conference, SABI 2011 and 7th Clinical Engineering Meeting, vol. 332, no. 1, 2011.
http://dx.doi.org/10.1088/1742-6596/332/1/012028
---------- VANCOUVER ----------
Ruiz, I., Hermida, É.B., Baldessari, A. Fabrication and characterization of porous PHBV scaffolds for tissue engineering. J. Phys. Conf. Ser. 2011;332(1).
http://dx.doi.org/10.1088/1742-6596/332/1/012028