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Abstract:

Innate responses in animals can be modulated by experience. Disturbed adults of the triatomine bug Triatoma infestans release an alarm pheromone (AP) that elicits an escape response in conspecific larvae. The main component of this AP, the isobutyric acid (IsoAc), alone has already shown to generate an escape response in this species. However, not much is known about the modulation of this behavior by non-associative and associative cognitive processes. We present here evidences of the cognitive capacities of T. infestans larvae in an escape context under different conditioning paradigms, including IsoAc in different roles. We show that: 1) the duration of a preexposure to IsoAc plays a main role in determining the type of non-associative learning expressed: short time pre-exposures elicit a sensitization while a longer pre-exposure time triggers a switch from repellence to attractiveness; 2) a simple pre-exposure event is enough to modulate the escape response of larvae to the AP and to its main component: IsoAc; 3) IsoAc and the AP are perceived as different chemical entities; 4) an association between IsoAc and an aversive stimulus can be created under a classical conditioning paradigm; 5) an association between IsoAc and a self-action can be generated under an operant conditioning. These results evince that IsoAc can attain multiple and different cognitive roles in the modulation of the escape response of triatomines and show how cognitive processes can modulate a key behavior for surviving, as it is the escaping response in presence of a potential danger in insects. © 2013 Minoli, Palottini and Manrique.

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Documento: Artículo
Título:The main component of an alarm pheromone of kissing bugs plays multiple roles in the cognitive modulation of the escape response
Autor:Minoli, S.; Palottini, F.; Manrique, G.
Filiación:Laboratorio de Fisiología de Insectos, Departamento de Biodiversidad, Argentina
Biología Experimental, Argentina
Naturales, Universidad de Buenos Aires, IBBEA, CONICET-UBA, Ciudad Autónoma de Buenos Aires, Argentina
Palabras clave:Alarm-pheromone; Associative; Learning; Non-associative; Plasticity; Triatomines; isobutyric acid; pheromone; animal experiment; article; aversion; cognition; conditioning; controlled study; escape behavior; habituation; hazard; insect; larva; learning; nonhuman; olfactometry; place preference; sensitization; smelling; state dependent learning; stimulus response; survival rate; Triatominae
Año:2013
Número:JUN
DOI: http://dx.doi.org/10.3389/fnbeh.2013.00077
Título revista:Frontiers in Behavioral Neuroscience
Título revista abreviado:Front. Behav. Neurosci.
ISSN:16625153
CAS:isobutyric acid, 5711-69-3, 79-31-2
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_16625153_v_nJUN_p_Minoli

Referencias:

  • Aggio, J., Rakitin, A., Maldonado, H., Serotonin-induced short- and longterm sensitization in the crab Chasmagnathus (1996) Pharmacol. Biochem. Behav, 53, p. 441448
  • Alonso, W.J., Wyatt, T.D., Kelly, D.W., Are vectors able to learn about their hosts? A case study with Aedes aegypti mosquitoes (2003) Mem. Inst. Oswaldo Cruz, 98, p. 665672
  • Anderson, P., Sadek, M.M., Hansson, B.S., Pre-exposure Modulates Attraction to Sex Pheromone in a Moth (2003) Chem. Senses, 28, pp. 285-291
  • Anderson, P., Hansson, B.S., Nilsson, U., Han, Q., Sjoholm, M., Skals, N., Anton, S., Increased Behavioral and Neuronal Sensitivity to Sex Pheromone after Brief Odor Experience in a Moth (2007) Chem. Senses, 32, pp. 483-491
  • Anton, S., Evengaard, K., Barrozo, R.B., Anderson, P., Skals, N., Brief predator sound exposure elicits behavioral and neuronal long-term sensitization in the olfactory system of an insect (2011) Proc. Natl. Acad. Sci, 108 (8), pp. 3401-3405. , U.S.A.
  • Bitterman, M.E., Menzel, R., Fietz, A., Schafer, S., Classical conditioning of proboscis extension in honeybees (Apis mellifera) (1983) J. Comp. Psychol, 97, pp. 107-119
  • Braun, G., Bicker, G., Habituation of an appetitive reflex in the honeybee (1992) J. Neurophysiol, 67, pp. 588-598
  • Brindley, M.D.H., On the metasternal scent-glands of certain Heteroptera (1930) T. Roy. Ent. Soc. London, 78, pp. 199-208
  • Cork, A., Park, K.C., Identification of electrophysiologically-active compounds for the malaria mosquito, Anopheles gambiae, in human sweat extracts (1996) Med. Vet. Entomol, 10, pp. 269-276
  • Crespo, J.G., Manrique, G., Mating behavior of the hematophagous bug Triatoma infestans: Role of Brindley's and metasternal glands (2007) J. Insect Physiol, 53, pp. 708-714
  • Cruz-López, L., Morgan, E.D., Ondarza, R.N., Brindley's gland exocrine products of Triatoma infestans (1995) Med. Vet. Entomol, 9, pp. 403-406
  • Duerr, J.S., Quinn, W.G., Three Drosophila mutations that block associative learning also affect habituation and sensitization (1982) Proc. Natl. Acad. Sci, 79, pp. 3646-3650. , U.S.A
  • Grubb, M.S., Thompson, I.D., The influence of early experience on the development of sensory systems (2004) Curr. Opin. Neurobiol, 14, pp. 503-512
  • Guerenstein, P.G., Guerin, P.M., Olfactory and behavioural responses of the blood-sucking bug Triatoma infestans to odours of vertebrate hosts (2001) J. Exp. Biol, 204, pp. 585-597
  • Guerrieri, F., Gemeno, C., Monsempes, C., Anton, S., Jacquin-Joly, E., Lucas, P., Devaud, J.M., Experience-dependent modulation of antennal sensitivity and input to antennal lobes in male moths (Spodoptera littoralis) pre-exposed to sex pheromone (2012) J. Exp. Biol, 215, pp. 2334-2341
  • Hammer, M., Braun, G., Mauelshagen, J., Food-induced arousal and non- associative learning in honeybees: Dependence of sensitization on the application site and duration of food stimulation (1994) Behav Neural Biol, 62, pp. 210-223
  • Heisenberg, M., Borst, A., Wagner, S., Byers, D., Drosophila Mushroom Body Mutants are Deficient in Olfactory Learning (1985) J. Neurogen, 2, pp. 1-30
  • Kalin, M., Barrett, F.M., Observations on the anatomy, histology, release site, and function of Brindley's glands in the blood-sucking bug, Rhodnius prolixus (Heteroptera: Reduviidae) (1975) Ann. Entomol. Soc. Am, 68, pp. 126-134
  • Kaur, J.S., Lai, Y.L., Giger, A.D., Learning and memory in the mosquito Aedes aegypti shown by conditioning against oviposition deterrence (2003) Med. Vet. Entomol, 17, pp. 457-460
  • Lazzari, C.R., Circadian organization of locomotion activity in the haematophagous bug Triatoma infestans (1992) J. Insect Physiol, 38, pp. 895-903
  • Manrique, G., Lorenzo, M.G., The sexual behavior of Chagas' Disease vectors: Chemical signals mediating communication between male and female Triatomine bugs (2012) Psyche, p. 2012. , doi:10.1155/2012/862891
  • Manrique, G., Vitta, A., Ferreira, R., Zani, C., Unelius, C., Lazzari, C., Diotaiuti, L., Lorenzo, M., Chemical communication in Chagas Disease vectors. Source, identity, and potential function of volatiles released by the Metasternal and Brindley's glands of Triatoma infestans adults (2006) J. Chem. Ecol, 32, pp. 2035-2052
  • McCall, P.J., Eaton, G., Olfactory memory in the mosquito Culex quinquefasciatus (2001) Med. Vet. Entomol, 15, pp. 197-203
  • McCall, P.J., Kelly, D.W., Learning and memory in disease vectors (2002) Trends Parasitol, 18, pp. 429-433
  • McCall, P.J., Mosha, F.W., Njunwa, K.J., Sherlock, K., Evidence for memorized site-fidelity in Anopheles arabiensis (2001) T. Roy. Soc. Trop. Med. Hyg, 95, pp. 587-590
  • Menzel, R., Muller, U., Learning and memory in honeybees: From behavior to neural substrates (1996) Annu. Rev. Neurosci, 19, pp. 379-404
  • Minoli, S., Kauer, I., Colson, V., Party, V., Renou, M., Anderson, P., Gadenne, C., Anton, S., Brief Exposure to Sensory Cues Elicits Stimulus-Nonspecific General Sensitization in an Insect (2012) PLoS ONE, e34141, p. 7
  • Monteith, L.G., Habituation and Associative Learning in Drino bohémica Mesn. (Diptera: Tachinidae) (1963) Can. Entomol, 95, pp. 418-426
  • Pavlov, I.P., (1929) Conditioned Reflexes: An Investigation of the Physiological Activity of the Cerebral Cortex, , Ed: Oxford University Press: Humphrey Milford, London
  • Pelz, C., Gerber, B., Menzel, R., Odorant intensity as a determinant for olfactory conditioning in honeybees: Roles in discrimination, overshadowing and memory consolidation (1997) J. Exp. Biol, 200, pp. 837-847
  • Pontes, G., Bohman, B., Unelius, C.R., Lorenzo, M., Metasternal gland volatiles and sexual communication in the triatomine bug, Rhodnius prolixus (2008) J. Chem. Ecol, 34, pp. 450-457
  • Pontes, G., Lorenzo, M.G., Female metasternal gland odors mediate male aggregation in Rhodnius prolixus, a triatomid bug (2012) Med. Vet. Entomol, 26, pp. 33-36
  • Rakitin, A., Tomsic, D., Maldonado, H., Habituation and sensitization to an electrical shock in the crab Chasmagnathus. Effect of background illumination (1991) Physiol. Behav, 50, pp. 477-487
  • Rojas, J.C., Rios-Candelaria, E., Cruz-Lopez, L., Santiesteban, A., Bond-Compean, J.G., Brindis, Y., Malo, E.A., A reinvestigation of Brindley's gland exocrine compounds of Rhodnius prolixus (Hemiptera: Reduviidae) (2002) J. Med. Entomol, 39, p. 25665
  • Schacter, D.L., Buckner, R.L., Priming and the Brain (1998) Neuron, 20 (2), pp. 185-195
  • Schofield, C., Upton, C.P., Brindley's scent-glands and the metasternal scent- glands of Panstrongylus megistus (Hemiptera, Reduviidae, Triatominae) (1978) Rev. Bras. Biol, 38, pp. 665-678
  • Schofield, C.J., Demonstration of isobutyric acid in some triatomine bugs (1979) Acta Trop, 36, pp. 103-105
  • Skinner, B.F., Two types of conditioned reflex: A reply to Konorski and Miller (1937) J. Gen. Psychol, 16, pp. 272-279
  • Vinauger, C., Buratti, L., Lazzari, C.R., Learning the way to blood: First evidence of dual olfactory conditioning in a blood-sucking insect, Rhodnius prolixus (2011) I. Appetitive Learning. J. Exp. Biol, 214, pp. 3032-3038
  • Vinauger, C., Buratti, L., Lazzari, C.R., Learning the way to blood: First evidence of dual olfactory conditioning in a blood-sucking insect, Rhodnius prolixus. II. Aversive learning (2011) J. Exp. Biol, 214, pp. 3039-3045
  • Vinauger, C., Pereira, M.H., Lazzari, C.R., Learned host preference in a Chagas disease vector, Rhodniusprolixus (2012) Acta Trop, 122, pp. 24-28
  • Vitta, A., Bohman, B., Unelius, C., Lorenzo, M., Behavioral and electrophysiological responses of Triatoma brasiliensis males to volatiles produced in the Metasternal glands of females (2009) J. Chem. Ecol, 35, pp. 1212-1221
  • Walters, E., Illich, P., Weeks, J., Lewin, M., Defensive responses of larval Manduca sexta and their sensitization by noxious stimuli in the laboratory and field (2001) J. Exp. Biol, 204, pp. 457-469
  • Ward, J.P., A comparison of the behavioural responses of the haematophagous bug, Triatoma infestans to synthetic homologues of two naturally occurring chemicals (n- and isobutyric acid) (1981) Physiol. Entomol, 6, pp. 325-329
  • Zacharias, C., Pontes, G., Lorenzo, M., Manrique, G., Flight initiation by male Rhodnius prolixus is promoted by female odors (2010) J. Chem. Ecol, 36, pp. 449-451

Citas:

---------- APA ----------
Minoli, S., Palottini, F. & Manrique, G. (2013) . The main component of an alarm pheromone of kissing bugs plays multiple roles in the cognitive modulation of the escape response. Frontiers in Behavioral Neuroscience(JUN).
http://dx.doi.org/10.3389/fnbeh.2013.00077
---------- CHICAGO ----------
Minoli, S., Palottini, F., Manrique, G. "The main component of an alarm pheromone of kissing bugs plays multiple roles in the cognitive modulation of the escape response" . Frontiers in Behavioral Neuroscience, no. JUN (2013).
http://dx.doi.org/10.3389/fnbeh.2013.00077
---------- MLA ----------
Minoli, S., Palottini, F., Manrique, G. "The main component of an alarm pheromone of kissing bugs plays multiple roles in the cognitive modulation of the escape response" . Frontiers in Behavioral Neuroscience, no. JUN, 2013.
http://dx.doi.org/10.3389/fnbeh.2013.00077
---------- VANCOUVER ----------
Minoli, S., Palottini, F., Manrique, G. The main component of an alarm pheromone of kissing bugs plays multiple roles in the cognitive modulation of the escape response. Front. Behav. Neurosci. 2013(JUN).
http://dx.doi.org/10.3389/fnbeh.2013.00077