Artículo

Estamos trabajando para incorporar este artículo al repositorio
Consulte el artículo en la página del editor
Consulte la política de Acceso Abierto del editor

Abstract:

A specially designed electronic nose was coupled to an air-lift bioreactor in order to perform on-line monitoring of released vapors. The sensor array was placed at the top of the bioreactor sensing the headspace in equilibrium with the evolving liquor at any time without the need of aspiration and pumping of gases into a separated sensor chamber. The device was applied to follow the off-gas of a bioreactor with Acidithiobacillus thiooxidans grown on beds of elemental sulfur under aerobic conditions. Evolution was monitored by acid titration, pH and optical density measurements. The electronic nose was capable to differentiate each day of reactor evolution since inoculation within periods marked off culture medium replacements using multivariate data analysis. Excellent discrimination was obtained indicating the potentiality for on-line monitoring in non-perturbed bioreactors. The prospects for electronic nose/bioreactor merging are valuable for whatever the bacterial strain or consortium used in terms of scent markers to monitor biochemical processes. © Springer-Verlag 2011.

Registro:

Documento: Artículo
Título:Customized design of electronic noses placed on top of air-lift bioreactors for in situ monitoring the off-gas patterns
Autor:Rosi, P.E.; Miscoria, S.A.; Bernik, D.L.; Martín Negri, R.
Filiación:Departamento de Química Inorgánica, Analítica Y Química Física, Instituto de Quimica Fisica de Los Materiales, Medio Ambiente Y Energia (INQUIMAE), Universidad de Buenos Aires, C1428EGA Buenos Aires, Argentina
Departamento de Química, Facultad de Ciencias Naturales, Universidad Nacional de la Patagonia, San Juan Bosco, Argentina
Palabras clave:Bioreactors; Electronic nose; Gas monitoring; Non-invasive control; Real-time measurement; Sensor array; Acid titration; Acidithiobacillus thiooxidans; Aerobic condition; Air-lift bioreactors; Bacterial strains; Biochemical process; Culture medium; Electronic NOSE; Elemental sulfur; Gas monitoring; Headspaces; In-situ monitoring; Multivariate data analysis; Online monitoring; Real time measurements; Artificial organs; Bioreactors; Density measurement (optical); Electronic equipment; Sensor arrays; Sensors; Sulfur; Voltage measurement; Bioconversion; sulfur; Acidithiobacillus thiooxidans; acidity; airlift reactor; analytic method; article; automated pattern recognition; bacterial growth; controlled study; electronic nose; electronic sensor; gas evolution; inoculation; nonhuman; online monitoring; optical density; priority journal; signal processing; titrimetry; vapor; Acidithiobacillus thiooxidans; Bioreactors; Gases; Acidithiobacillus thiooxidans; Bacteria (microorganisms)
Año:2012
Volumen:35
Número:5
Página de inicio:835
Página de fin:842
DOI: http://dx.doi.org/10.1007/s00449-011-0667-z
Título revista:Bioprocess and Biosystems Engineering
Título revista abreviado:Bioprocess Biosyst. Eng.
ISSN:16157591
CODEN:BBEIB
CAS:sulfur, 13981-57-2, 7704-34-9; Gases
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_16157591_v35_n5_p835_Rosi

Referencias:

  • Caccavale, F., Iamarino, M., Pierri, F., Tufano, V., (2011) Control and Monitoring of Chemical Batch Reactors, , Springer, London
  • Bendriaa, L., Picart, P., Daniel, P., Horry, H., Durand, M.-J., Thouand, G., Versatile device for on-line and in-situ measurement of growth and light production of bioluminescent cells (2004) Sensors and Actuators, B: Chemical, 103 (1-2), pp. 115-121. , DOI 10.1016/j.snb.2004.04.043, PII S0925400504002217, The 17th European Conference on Solid-State Transducers, University of Minho, Guimares, Portugal, September 21-24, 2003
  • Bartlett, P.N., Gardner, J.W., (1999) Electronic Noses: Principles and Applications, , Oxford University Press, Oxford
  • Buczkowskaa, A., Witkowskaa, E., Górski, Ł., Zamojskab, A., Szewczykb, K.W., Wróblewski, W., Cioseka, P., The monitoring of methane fermentation in sequencing batch bioreactor with flow-through array of miniaturized solid state electrodes (2010) Talanta, 81, pp. 1387-1392
  • Soderstrom, C., Rudnitskaya, A., Legin, A., Krantz-Rulcker, C., Differentiation of four Aspergillus species and one Zygosaccharomyces with two electronic tongues based on different measurement techniques (2005) Journal of Biotechnology, 119 (3), pp. 300-308. , DOI 10.1016/j.jbiotec.2005.04.017, PII S0168165605001896
  • Kim, N., Park, K.-R., Park, I.-S., Cho, Y.-J., Bae, Y.M., Application of a taste evaluation system to the monitoring of Kimchi fermentation (2005) Biosensors and Bioelectronics, 20 (11), pp. 2283-2291. , DOI 10.1016/j.bios.2004.10.007
  • Legin, A., Kirsanov, D., Rudnitskaya, A., Iversen, J.J.L., Seleznev, B., Esbensen, K.H., Mortensen, J., Vlasov, Y., Multicomponent analysis of fermentation growth media using the electronic tongue (2004) Talanta, 64, pp. 766-772
  • Ahring, B., Sandberg, M., Angelidaki, I., Volatile fatty acids as indicators of process imbalance in anaerobic digestors (1995) Appl Microbiol Biotechnol, 43, pp. 559-565
  • Moletta, R., Escoffier, Y., Ehrlinger, F., Coudert, J.P., Leyris, J.P., On-line automatic control system for monitoring an anaerobic fluidized-bead reactor: Response to organic overload (1994) Water Sci Technol, 30, pp. 11-20
  • Bhattacharya, N., Tudu, B., Jana, A., Ghosh, D., Bandhopadhyaya, R., Bhuyan, M., Preemptive identification of optimum fermentation time for black tea using electronic nose (2008) Sensors and Actuators, B: Chemical, 131 (1), pp. 110-116. , DOI 10.1016/j.snb.2007.12.032, PII S0925400507009938
  • Rudnitskaya, A., Legin, A., Sensor systems, electronic tongues and electronic noses, for the monitoring of biotechnological processes (2008) J Ind Microbiol Biotechnol, 35, pp. 443-451
  • Maciejewska, M., Szczurek, A., Kerenyi, Z., Utilization of first principal component extracted from gas sensor measurements as a process control variable in wine fermentation (2006) Sens Actuators B Chem, 115, pp. 170-177
  • Pavlou, A.K., Magan, N., Jones, J.M., Brown, J., Klatser, P., Turner, A.P.F., Detection of Mycobacterium tuberculosis (TB) in vitro and in situ using an electronic nose in combination with a neural network system (2004) Biosensors and Bioelectronics, 20 (3), pp. 538-544. , DOI 10.1016/j.bios.2004.03.002, PII S0956566304001204, Optical Biosensing
  • Clemente, J.J., Monteiro, S.M.S., Carrondo, M.J.T., Cunha, A.E., Predicting sporulation events in a bioreactor using an electronic nose (2008) Biotechnol Bioeng, 101, pp. 545-552
  • Kreij, K., Mandenius, C.-F., Clemente, J.J., Cunha, A.E., Monteiro, S.M.S., Carrondo, M.J.T., Hesse, F., Mitrovics, J., On-line detection of microbial contaminations in animal cell reactor cultures using an electronic nose device (2005) Cytotechnology, 48 (1-3), pp. 41-58. , DOI 10.1007/s10616-005-3587-4
  • Cimander, C., Carlsson, M., Mandenius, C.-F., Sensor fusion for on-line monitoring of yoghurt fermentation (2002) Journal of Biotechnology, 99 (3), pp. 237-248. , DOI 10.1016/S0168-1656(02)00213-4, PII S0168165602002134
  • Bachinger, T.., Riese, U., Eriksson, R.K., Mandenius, C.F., Electronic nose for estimation of product concentration in mammalian cell cultivation (2000) Bioprocess Engineering, 23 (6), pp. 637-642. , DOI 10.1007/s004490000213
  • Rodríguez, S.D., Monge, M.E., Olivieri, A.C., Negri, R.M., Bernik, D.L., Time dependence of the aroma pattern emitted by an encapsulated essence studied by means of electronic noses and chemometric analysis (2010) Food Res Int, 43, pp. 797-804
  • Eugenia, M.M., Martin, N.R., Giacomazza, D., Bulone, D., Correlation between rheological properties and limonene release in pectin gels using an electronic nose (2008) Food Hydrocolloids, 22 (5), pp. 916-924. , DOI 10.1016/j.foodhyd.2007.05.004, PII S0268005X07001312
  • Negri, R.M., Bernik, D.L., Tracking the sex pheromone of codling moth against a background of host volatiles with an electronic nose (2008) Crop Prot, 27, pp. 1295-1302
  • Diz, V., Cassanello, M., Negri, R.M., Detection and discrimination of phenol and primary alcohols in water using electronic noses (2006) Environmental Science and Technology, 40 (19), pp. 6058-6063. , DOI 10.1021/es052322e
  • Lovino, M., Cardinal, M.F., Zubiri, D.B.V., Bernik, D.L., Electronic nose screening of ethanol release during sol-gel encapsulation: A novel non-invasive method to test silica polymerisation (2005) Biosensors and Bioelectronics, 21 (6), pp. 857-862. , DOI 10.1016/j.bios.2005.02.003, PII S0956566305000394
  • Monge, M.E., Bulone, D., Giacomazza, D., Bernik, D.L., Negri, R.M., Detection of flavour release form pectin gels using electronic noses (2004) Sens Actuators B Chem, 101, pp. 28-38
  • Monge, M.E., Bulone, D., Giacomazza, D., Negri, R.M., Bernik, D.L., Electronic nose screening of limonene release from multicomponent essential oils encapsulated in pectin gels (2004) Combinatorial Chemistry and High Throughput Screening, 7 (4), pp. 337-344
  • Branca, A., Simonian, P., Ferrante, M., Novas, E., Negri, R.M., Electronic nose based discrimination of a perfumery compound in a fragrance (2003) Sens Actuators B-Chem, 92, pp. 222-227
  • O'Connell, M., Valdora, G., Peltzer, G., Martin, N.R., A practical approach for fish freshness determinations using a portable electronic nose (2001) Sensors and Actuators, B: Chemical, 80 (2), pp. 149-154. , DOI 10.1016/S0925-4005(01)00904-2, PII S0925400501009042
  • Bredberg, K., Karlsson, H.T., Holst, O., Reduction of vanadium(V) with Acidithiobacillus ferrooxidans and Acidithiobacillus thiooxidans (2004) Bioresource Technology, 92 (1), pp. 93-96. , DOI 10.1016/j.biortech.2003.08.004
  • Gargarello, R.M., Di Gregorio, D., Huck, H., Fernandez Niello, J., Curutchet, G., Reduction of uranium(VI) by Acidithiobacillus thiooxidans and Acidithiobacillus ferrooxidans (2010) Hydrometallurgy, 104, pp. 529-532
  • Johnson, R.A., Wichern, D.W., (2002) Applied Multivariate Statistical Analysis, , Prentice Hall, New Jersey
  • Struyf, A., Hubert, M., Rousseeuw, P.J., Integrating robust clustering techniques in S-PLUS (1997) Comput Stat Data Anal, 26, pp. 17-37
  • Kaufman, L., Rousseeuw, P.J., (1987) Statistical Data Analysis Based on the L1 Norm In: Clustering by Means of Medoids, , Elsevier/ North Holland, Amsterdam
  • Mandenius, C.F., (1999) Advances in Biochemical Engineering/biotechnology, , Scheper T (ed) Springer, Berlin
  • Choi, D.W., Lee, W.L., Lim, S.J., Kim, B.J., Chang, H.N., Chang, S.T., Simulation on long-term operation of an anaerobic bioreactor for Korean food wastes (2003) Biotechnol Bioprocess Eng, 8, pp. 23-31
  • Malakahmad, A., Zain, S.M., Ahmad Basri, N.E., Mohamed Kutty, S.R., Isa, M.H., Identification of anaerobic microorganisms for converting kitchen waste to biogas (2009) World Acad Sci Eng Technol, 60, pp. 882-885
  • Fernández, M.R., Bernik, D.L., Whole-cell biosensors: Research and patents (2010) Recent Pat Biomed Eng, 3, pp. 138-146

Citas:

---------- APA ----------
Rosi, P.E., Miscoria, S.A., Bernik, D.L. & Martín Negri, R. (2012) . Customized design of electronic noses placed on top of air-lift bioreactors for in situ monitoring the off-gas patterns. Bioprocess and Biosystems Engineering, 35(5), 835-842.
http://dx.doi.org/10.1007/s00449-011-0667-z
---------- CHICAGO ----------
Rosi, P.E., Miscoria, S.A., Bernik, D.L., Martín Negri, R. "Customized design of electronic noses placed on top of air-lift bioreactors for in situ monitoring the off-gas patterns" . Bioprocess and Biosystems Engineering 35, no. 5 (2012) : 835-842.
http://dx.doi.org/10.1007/s00449-011-0667-z
---------- MLA ----------
Rosi, P.E., Miscoria, S.A., Bernik, D.L., Martín Negri, R. "Customized design of electronic noses placed on top of air-lift bioreactors for in situ monitoring the off-gas patterns" . Bioprocess and Biosystems Engineering, vol. 35, no. 5, 2012, pp. 835-842.
http://dx.doi.org/10.1007/s00449-011-0667-z
---------- VANCOUVER ----------
Rosi, P.E., Miscoria, S.A., Bernik, D.L., Martín Negri, R. Customized design of electronic noses placed on top of air-lift bioreactors for in situ monitoring the off-gas patterns. Bioprocess Biosyst. Eng. 2012;35(5):835-842.
http://dx.doi.org/10.1007/s00449-011-0667-z