Conferencia
Miskoski, S.; Giordano, L.; Etchehon, M.H.; Menendez, G.; Lidke, K.A.; Hagen, G.M.; Jovin, T.M.; Jares-Erijman, E.A. "Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors" (2006) Colloidal Quantum Dots for Biomedical Applications. 6096
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Abstract:
Multifunctional nanoparticles, quantum dots (QDs) are being developed as uniquely sensitive tools for elucidating the (bio)chemical and (bio)physical molecular mechanisms underlying functional states, i.e. the molecular physiology, of biological cells and organisms. Here we present a group of strategies and examples for (i) controlling the spectroscopic properties of QDs via Fluorescence Resonance Energy Transfer (FRET); (ii) determining the emission spectra of individual QDs in a population with an imaging spectrograph (ASI SpectraCube); and (iii) employing such liganded QDs as nano-probes in cellular studies of signal transduction.
Registro:
| Documento: | Conferencia |
| Título: | Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors |
| Autor: | Miskoski, S.; Giordano, L.; Etchehon, M.H.; Menendez, G.; Lidke, K.A.; Hagen, G.M.; Jovin, T.M.; Jares-Erijman, E.A. |
| Ciudad: | San Jose, CA |
| Filiación: | Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria-Pabellón II, 1428 Buenos Aires, Argentina Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, D-37077 Göttingen, Germany Sandia Laboratories, Albuquerque, NM 87185, United States |
| Palabras clave: | EGF receptor; FRET; Nanoparticle; pcFRET; Photochromism; Quantum dot; SpectraCube; EGF receptors; Fluorescence Resonance Energy Transfer (FRET); PcFRET; SpectraCube; Biomedical engineering; Cells; Medical applications; Medical imaging; Nanostructured materials; Photochromism; Probes; Semiconductor quantum dots |
| Año: | 2006 |
| Volumen: | 6096 |
| DOI: | http://dx.doi.org/10.1117/12.649835 |
| Título revista: | Colloidal Quantum Dots for Biomedical Applications |
| Título revista abreviado: | Progr. Biomed. Opt. Imaging Proc. SPIE |
| ISSN: | 16057422 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_16057422_v6096_n_p_Miskoski |
Referencias:
- Jares-Erijman, E.A., Jovin, T.M., FRET imaging (2003) Nat. Biotech., 21, pp. 1387-1395
- Grecco, H.E., Ensemble and single particle photophysical propeties (two-photon excitation, anisotropy, FRET, lifetime, spectral conversion) of commercial quantum dots in solution and in live cells (2004) Microsc. Res. Tech., 65, pp. 169-179
- Medintz, I.L., Quantum dot bioconjugates for imaging, labelling and sensing (2005) Nat. Mat., 4, pp. 435-446
- Medintz, I.L., A fluorescence resonance energy transfer-derived structure of a quantum dot-protein bioconjugate nanoassembly (2004) Proc. Nat. Acad. Sci. U.S.A., 101, pp. 9612-9617
- Medintz, I.L., A fluorescence resonance energy transfer sensor based on maltose binding protein (2003) Bioconj. Chem., 14, pp. 909-918
- Lidke, D.S., Reaching out for signals: Filopodia sense EGF and respond by directed retrograde transport of activated receptors (2005) J. Cell Biol., 170, pp. 619-626
- Heintzmann, R., Lidke, K.A., Jovin, T.M., Double-pass Fourier transform imaging spectroscopy (2004) Optics Expr., 12, pp. 753-763
- Song, L., Jares-Erijman, E.A., Jovin, T.M., A photochromic acceptor as a reversible light-driven switch in fluorescence resonance energy transfer (FRET) (2002) J. Photochem. Photobiol. A-chem., 150, pp. 177-185
- Giordano, L., Diheteroarylethenes as thermally stable photoswitchable acceptors in photochromic fluorescence resonance energy transfer (pcFRET) (2002) J. Am. Chem. Soc., 124, pp. 7481-7489
- Jares-Erijman, E.A., Imaging quantum dots switched on and off by photochromic fluorescence resonance energy transfer (pcFRET) (2005) Molec. Cryst. Liq. Cryst., 430, pp. 257-265
- Giordano, L., Vermeij, R.J., Jares-Erijman, E.A., Synthesis of indole-containing diheteroarylethenes. New probes for photochromic FRET (pcFRET) (2005) Arkivoc, PART XII, pp. 268-281
- Giordano, L., Jares-Erijman, E.A., manuscript in preparation; Giordano, L., (2006), PhD Thesis, Univ. of Buenos AiresA4 - SPIE
Citas:
---------- APA ----------
Miskoski, S., Giordano, L., Etchehon, M.H., Menendez, G., Lidke, K.A., Hagen, G.M., Jovin, T.M.,..., Jares-Erijman, E.A. (2006) . Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors. Colloidal Quantum Dots for Biomedical Applications, 6096.http://dx.doi.org/10.1117/12.649835
---------- CHICAGO ----------
Miskoski, S., Giordano, L., Etchehon, M.H., Menendez, G., Lidke, K.A., Hagen, G.M., et al. "Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors" . Colloidal Quantum Dots for Biomedical Applications 6096 (2006).http://dx.doi.org/10.1117/12.649835
---------- MLA ----------
Miskoski, S., Giordano, L., Etchehon, M.H., Menendez, G., Lidke, K.A., Hagen, G.M., et al. "Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors" . Colloidal Quantum Dots for Biomedical Applications, vol. 6096, 2006.http://dx.doi.org/10.1117/12.649835
---------- VANCOUVER ----------
Miskoski, S., Giordano, L., Etchehon, M.H., Menendez, G., Lidke, K.A., Hagen, G.M., et al. Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors. Progr. Biomed. Opt. Imaging Proc. SPIE. 2006;6096.http://dx.doi.org/10.1117/12.649835
