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Referencias:

• Luteijn, J.M., White, B.C., Gunnlaugsdóttir, H., State of the art in benefit-risk analysis: Medicines (2012) Food Chem Toxicol, 50, pp. 26-32
• Freeman, C.D., Klutman, E.N., Lamp, K.C., Metronidazole: A therapeutic review and update (1997) Drugs, 54, pp. 679-708
• Barbut, F., Meynard, J.L., Eckert, C., Traitement des infections digestives à Clostridium difficile: Anciennes et nouvelles approches (2011) J Anti-infec, 13, pp. 74-86
• Bendeski, A., Menéndez, D., Ostrosky-Wegman, P., Is metronidazole carcinogenic? (2002) Mutat Res, 511, pp. 133-144
• Mylonas, I., Antibiotic chemotherapy during pregnancy and lactation period: Aspects for consideration (2011) Arch Gynecol Obstet, 283, pp. 7-18
• Dobías, L., Cerna, M., Rossner, P., Sram, R., Genotoxicity and carcinogenicity of metronidazole (1994) Mutat Res, 317, pp. 177-194
• Rodriguez Ferreiro, G., Cancino Badias, L., Lopez-Nigro, M., DNA single strand breaks in peripheral blood lymphocytes induced by three nitroimidazole derivatives (2002) Tox Lett, 132, pp. 109-115
• López Nigro, M.M., Palermo, A.M., Mudry, M.D., Carballo, M.A., Cytogenetic evaluation of two nitroimidazole derivatives (2003) Toxicol In Vitro, 17, pp. 35-40
• Palermo, A.M., Mudry, M.D., Reynoso, A.S., López Nigro, M., Carballo, M.A., Teratogenic evaluation of metronidazole and ornidazole using Drosophila melanogaster as an experimental model (2004) Birth Defects Res, 70, pp. 157-162
• Ornelas-Aguirre, J.M., Gómez-Meda, B.C., Zamora-Pérez, A.L., Ramos Ibarra, M.L., Batista-González, C.M., Zuñiga-González, G.M., Micronucleus Induction by Metronidazole in rat vaginal mucosa (2006) Environ Mol Mutagen, 47, pp. 352-356
• Abrevaya, X., Carballo, M.A., Mudry, M.D., The bone marrow micronucleus test and metronidazole genotoxicity in different strains of mice (Mus musculus) (2007) Gen Mol Biol, 33, pp. 1139-1143
• Mudry, M.D., Carballo, M.A., Labal de Vinuesa, M., González Cid, M., Larripa, I., Mutagenic bioassay of certain pharmacological drugs. III. Metronidazol (MTZ) (1994) Mutat Res, 305, pp. 127-132
• Mudry, M.D., Martinez-Flores, I., Palermo, A.M., Carballo, M.A., Egozcue, J., García-Caldés, M., Embryolethality induced by metronidazole (MTZ) in Rattus norvegicus (2001) Teratogen Carcinog Mutag, 21, pp. 197-205
• Mudry, M.D., Palermo, A.M., Merani, M.S., Carballo, M.A., Metronidazole induced alterations in murine spermatozoa morphology (2007) Reprod Toxicol, 23, pp. 246-252
• Buschini, A., Ferrarini, L., Franzoni, S., Genotoxicity revaluation of three commercial nitroheterocyclic drugs: Nifurtimox, benznidazole, and metronidazole (2009) J Parasitol. Res (Online), p. 463575
• Sekis, I., Ramstead, K., Rishniw, M., Single-dose pharmacokinetics and genotoxicity of metronidazole in cats (2009) J Feline Med Surg, 11, pp. 60-68
• Graf, U., Würgler, F.E., Katz, A.J., Somatic mutation and recombination test in Drosophila melanogaster (1984) Environ Mutagen, 6, pp. 153-188
• Graf, U., Frei, H., Kägi, A., Katz, A.J., Würgler, F.E., Thirty compounds tested in the Drosophila wing spot test (1989) Mutat Res, 222, pp. 359-373
• Guzmán-Rincón, J., Graf, U., Drosophila melanogaster somatic mutation and recombination test as a biomonitor (1995) Biomonitors and Biomarkers As Indicators of Environmental Change, pp. 169-181. , Butterworth FM, Corkum LD, Guzmán Rincón J Eds, Plenum Press, New York
• Vogel, W., Graf, U., Frei, H.J., Nivard, M.M.J., The results of assays in Drosophila as indicators of exposure to carcinogens (1999) The Use of Short- and Medium-term Tests For Carcinogens and Data On Genetic Effects In Carcinogenic Hazard Evaluation, pp. 427-470. , In: McGregor DB, Rice JM, Venitt S, IARC Sc. Pub. 146
• Carmona, E.R., Kossatz, E., Creus, A., Marcos, R., Genotoxic evaluation of two mercury compounds in the Drosophila wing spot test (2008) Chemosphere, 70, pp. 1910-1914
• Demir, E., Marcos, R., Kaya, B., Genotoxicity studies in the ST cross of the Drosophila wing spot test of sunflower and soybean oils before and after frying and boiling procedures (2012) Food Chem Toxicol, 50, pp. 3619-3624
• Graf, U., Spanó, M.A., Guzmán Rincón, J., Abraham, S.K., Andrade, H.H., The wing Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster: An efficient tool for the detection of genotoxic activity of pure compounds or complex mixtures as well as for studies of antigenotoxicity (1996) Afr Newslett On Occup Health and Safety, 6 (SUPPL. 1), pp. 9-13
• Graf, U., Abraham, S.K., Guzmán-Rincón, J., Würgler, F.E., Antigenotoxicity studies in Drosophila melanogaster (1998) Mutat Res, 402, pp. 203-209
• Frei, H., Würgler, F.E., Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive negative or inconclusive result (1988) Mutat Res, 203, pp. 297-308
• Mohn, G.R., Ong, T., Callen, D.F., Kramers, P.N.G., Aron, C.S., Comparison of the genetic activity of 5-nitroimidazole derivatives in Escherichia coli, Neurospora crasa, Saccharomyces cerevisiae and Drososphila melanogaster (1976) J Environ Pathol Toxicol, 2, pp. 637-670
• Kramers, P.G.N., Studies on the induction of sex-linked recessive lethal mutations in Drosophila melanogaster by nitroheterocyclic compounds (1982) Mutat Res, 101, pp. 209-236
• Tripathy, N.K., Sahu, G.P., Anandkumar, A., Sahoo, U.R., Studies on the genotoxicity of two antiprotozoal and antibacterial agents in somatic and germ line cells of Drosophila (1996) Rev Int Contam Ambient, 12, pp. 83-88
• Rodriguez-Arnais, R., Hernández aranda, J., Metabolic activation of four drugs in the eye mosaic assay measuring principally mitotic recombination in Drosophila melanogaster: Differences in strain susceptibility and route of exposure (1994) Mutat Res, 305, pp. 157-163
• (2012), http://monographs.iarc.fr/ENG/Classification/index.php; Brambilla, G., Mattioli, F., Robbiano, L., Martelli, A., Update of carcinogenicity studies in animals and humans of 535 marketed pharmaceuticals (2012) Mutat Res, 750, pp. 1-51
• Nickoloff, J.A., Recombination: Mechanisms and Roles in Tumorigenesis (2002) Encyclopedia of Cancer, pp. 49-59. , In: Bertino, J. R., 2nd Ed.), Academic Press, New York
• Carballo, M.A., Martinez, R.A., Mudry, M.D., Nitroimidazole derivatives: Non-randomness sister chromatid exchanges in human peripheral blood lymphocytes (2008) J Appl Toxicol, 29, pp. 248-254
• López Nigro, M.M., Mudry, M.D., Carballo, M.A., Metronidazole: Short term tests and cell death induced under aerobic condition (2010) Lat Am J Pharm, 29, pp. 1319-1327
• Mudry, M.D., Martinez, R.A., Nieves, M., Carballo, M.A., Biomarkers of genotoxicity and genomic instability in a nonhuman primate Cebus libidinosus (Cebidae, Platyrrhini) (2011) Mutat Res, 721, pp. 108-113

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