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Abstract:

Sea cucumbers are characterized by their content in holothurins, triterpenoid glycosides that are responsible for the toxicity of these echinoderms. Nearly 100 holothurins isolated in the last twenty years are grouped into three main aglycone structural types: 3β-hydroxyholost-9(11)-ene, 3β-hydroxyholost-7-ene and non-holostane based aglycones. This communication offers a general view of the structural characteristics of these saponins and the spectral features in their 1H- and 13C-NMR and FAB-MS spectra. Recent advances in the unambiguous spectroscopic characterization of the triterpenoid skeleton, the substitution patterns and the complete structure of the oligosaccharide chain are discussed. © 2003 Elsevier B.V. All rights reserved.

Registro:

Documento: Artículo
Título:Biologically active triterpene glycosides from sea cucumbers (holothuroidea, echinodermata)
Autor:Chludil, H.D.; Murray, A.P.; Seldes, A.M.; Maier, M.S.
Filiación:Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, (1428) Buenos, Argentina
Año:2003
Volumen:28
Número:PART I
Página de inicio:587
Página de fin:615
DOI: http://dx.doi.org/10.1016/S1572-5995(03)80150-3
Título revista:Studies in Natural Products Chemistry
Título revista abreviado:Stud.Nat. Prod. Chem.
ISSN:15725995
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15725995_v28_nPARTI_p587_Chludil

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Citas:

---------- APA ----------
Chludil, H.D., Murray, A.P., Seldes, A.M. & Maier, M.S. (2003) . Biologically active triterpene glycosides from sea cucumbers (holothuroidea, echinodermata). Studies in Natural Products Chemistry, 28(PART I), 587-615.
http://dx.doi.org/10.1016/S1572-5995(03)80150-3
---------- CHICAGO ----------
Chludil, H.D., Murray, A.P., Seldes, A.M., Maier, M.S. "Biologically active triterpene glycosides from sea cucumbers (holothuroidea, echinodermata)" . Studies in Natural Products Chemistry 28, no. PART I (2003) : 587-615.
http://dx.doi.org/10.1016/S1572-5995(03)80150-3
---------- MLA ----------
Chludil, H.D., Murray, A.P., Seldes, A.M., Maier, M.S. "Biologically active triterpene glycosides from sea cucumbers (holothuroidea, echinodermata)" . Studies in Natural Products Chemistry, vol. 28, no. PART I, 2003, pp. 587-615.
http://dx.doi.org/10.1016/S1572-5995(03)80150-3
---------- VANCOUVER ----------
Chludil, H.D., Murray, A.P., Seldes, A.M., Maier, M.S. Biologically active triterpene glycosides from sea cucumbers (holothuroidea, echinodermata). Stud.Nat. Prod. Chem. 2003;28(PART I):587-615.
http://dx.doi.org/10.1016/S1572-5995(03)80150-3