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Abstract:

Dipeptidyl peptidase IV (DPPIV) is a well-characterized protease with broad substrate specificity, functionally-related to the activity of many bioactive peptides. It plays an important role as physiological regulator of a number of peptides that serve as biochemical messengers within the immune system. Plasma DPPIV activity was characterized with respect to temperature, kinetics and concentration dependence in two species of caiman, the broad-snouted caiman (Caiman latirostris) and the black yacare (Caiman yacare). DPPIV activity showed a significant positive correlation from titrations carried out in the presence of different plasma concentrations. DPPIV activity was lower in C. yacare than in C. latirostris at all temperatures tested. C. yacare DPPIV activity showed a significant increase only at higher temperatures whilst C. latirostris plasma demonstrated a strong positive correlation starting at the lowest temperature, probably due to an adaptation for the tolerance of lower temperatures. Exposure of C. latirostris and C. yacare plasma at different time points showed that plasma DPPIV activities were time-dependent, and that the titer-dependent curves were different for the two species. These results revealed that plasma DPPIV activities were different between these two crocodilian species, which could contribute to the differences in susceptibility to infection between them. © 2011 Koninklijke Brill NV, Leiden.

Registro:

Documento: Artículo
Título:Comparison of plasma dipeptidyl peptidase IV activity in two caiman species: Caiman latirostris and Caiman yacare (Crocodylia, Alligatoridae)
Autor:Siroski, P.A.; Merchant, M.E.; Marcó, M.P.V.; Poletta, G.L.; Ortega, H.H.
Filiación:Proyecto Yacaré, Laboratorio de Zoología Aplicada: Anexo Vertebrados (FHUC-UNL/MASPyMA), A. del Valle 8700, 3000 Santa Fe, Argentina
Secretaría de Estado de Medio Ambiente y Desarrollo Sustentable, 3000 Santa Fe, Argentina
Department of Chemistry, McNeese State University, Box 90455, Lake Charles, LA 70609, United States
Centro de Investigaciones Cientificas y Transferencia de Tecnologia la Produccion - CICyTTP, CONICET, 3105 Diamante, Entre Ríos, Argentina
Cátedra de Toxicología y Bioquímica Legal, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional Del Litoral, 3000 Santa Fe, Argentina
UBA - CONICET, C1428EGA Buenos Aires, Argentina
Departamento de Ciencias Morfológicas, Facultad de Ciencias Veterinarias, Universidad Nacional Del Litoral - CONICET, 3000 Santa Fe, Argentina
Palabras clave:broad-snouted caiman; crocodilian immune system; DPPIV; peptidases; yacare caiman; adaptive radiation; bioactivity; biochemical composition; comparative study; concentration (composition); correlation; crocodilian; enzyme activity; immune system; infectious disease; peptide; plasma; reaction kinetics; species diversity; temperature effect; tolerance; Alligatorinae; Caiman; Caiman latirostris; Caiman yacare; Crocodylidae (all crocodiles)
Año:2011
Volumen:61
Número:2
Página de inicio:199
Página de fin:210
DOI: http://dx.doi.org/10.1163/157075511X566524
Título revista:Animal Biology
Título revista abreviado:Anim. Biol.
ISSN:15707555
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15707555_v61_n2_p199_Siroski

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Citas:

---------- APA ----------
Siroski, P.A., Merchant, M.E., Marcó, M.P.V., Poletta, G.L. & Ortega, H.H. (2011) . Comparison of plasma dipeptidyl peptidase IV activity in two caiman species: Caiman latirostris and Caiman yacare (Crocodylia, Alligatoridae). Animal Biology, 61(2), 199-210.
http://dx.doi.org/10.1163/157075511X566524
---------- CHICAGO ----------
Siroski, P.A., Merchant, M.E., Marcó, M.P.V., Poletta, G.L., Ortega, H.H. "Comparison of plasma dipeptidyl peptidase IV activity in two caiman species: Caiman latirostris and Caiman yacare (Crocodylia, Alligatoridae)" . Animal Biology 61, no. 2 (2011) : 199-210.
http://dx.doi.org/10.1163/157075511X566524
---------- MLA ----------
Siroski, P.A., Merchant, M.E., Marcó, M.P.V., Poletta, G.L., Ortega, H.H. "Comparison of plasma dipeptidyl peptidase IV activity in two caiman species: Caiman latirostris and Caiman yacare (Crocodylia, Alligatoridae)" . Animal Biology, vol. 61, no. 2, 2011, pp. 199-210.
http://dx.doi.org/10.1163/157075511X566524
---------- VANCOUVER ----------
Siroski, P.A., Merchant, M.E., Marcó, M.P.V., Poletta, G.L., Ortega, H.H. Comparison of plasma dipeptidyl peptidase IV activity in two caiman species: Caiman latirostris and Caiman yacare (Crocodylia, Alligatoridae). Anim. Biol. 2011;61(2):199-210.
http://dx.doi.org/10.1163/157075511X566524