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Referencias:

• Bhatt, S., Gething, P.W., Brady, O.J., Messina, J.P., Farlow, A.W., The global distribution and burden of dengue (2013) Nature, 496, pp. 504-507. , 10.1038/nature12060, 23563266,–
• Gubler, D., Markoff, L., (2007) Flaviviruses, p. 1153
• Musso, D., Cao-Lormeau, V.M., Gubler, D.J., Zika virus: following the path of dengue and chikungunya? (2015) Lancet, 386, pp. 243-244. , 10.1016/S0140-6736(15)61273-9, 26194519–
• Fischl, W., Bartenschlager, R., Exploitation of cellular pathways by Dengue virus (2011) Curr Opin Microbiol, 14, pp. 470-475. , 10.1016/j.mib.2011.07.012, 21798792: –
• Morrison, J., Aguirre, S., Fernandez-Sesma, A., Innate immunity evasion by Dengue virus (2012) Viruses, 4, pp. 397-413. , 10.3390/v4030397, 22590678: –
• Jager, S., Gulbahce, N., Cimermancic, P., Kane, J., He, N., Purification and characterization of HIV-human protein complexes (2011) Methods, 53, pp. 13-19. , 10.1016/j.ymeth.2010.08.007, 20708689,–
• Germain, M.A., Chatel-Chaix, L., Gagne, B., Bonneil, E., Thibault, P., Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches (2014) Mol Cell Proteomics, 13, pp. 184-203. , 10.1074/mcp.M113.030155, 24169621,–
• Greninger, A.L., Knudsen, G.M., Betegon, M., Burlingame, A.L., Derisi, J.L., The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIbeta (2012) J Virol, 86, pp. 3605-3616. , 10.1128/JVI.06778-11, 22258260: –
• Komarova, A.V., Combredet, C., Meyniel-Schicklin, L., Chapelle, M., Caignard, G., Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses (2011) Mol Cell Proteomics, 10, p. M110. , 007443
• Lin, L., Li, Y., Pyo, H.M., Lu, X., Raman, S.N., Identification of RNA helicase A as a cellular factor that interacts with influenza A virus NS1 protein and its role in the virus life cycle (2012) J Virol, 86, pp. 1942-1954. , 10.1128/JVI.06362-11, 22171255,–
• Zhang, W., Du, J., Evans, S.L., Yu, Y., Yu, X.F., T-cell differentiation factor CBF-beta regulates HIV-1 Vif-mediated evasion of host restriction (2012) Nature, 481, pp. 376-379
• Egloff, M.P., Benarroch, D., Selisko, B., Romette, J.L., Canard, B., An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization (2002) Embo J, 21, pp. 2757-2768. , 12032088: –
• Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution (2007) J Virol, 81, pp. 4753-4765. , 17301146,–
• Ackermann, M., Padmanabhan, R., De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase (2001) J Biol Chem, 276, pp. 39926-39937. , 11546770: –
• Bartholomeusz, A.I., Wright, P.J., Synthesis of dengue virus RNA in vitro: initiation and the involvement of proteins NS3 and NS5 (1993) Arch Virol, 128, pp. 111-121. , 8418788: –
• Tan, B.H., Fu, J., Sugrue, R.J., Yap, E.H., Chan, Y.C., Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity (1996) Virology, 216, pp. 317-325. , 8607261,–
• Filomatori, C.V., Iglesias, N.G., Villordo, S.M., Alvarez, D.E., Gamarnik, A.V., RNA sequences and structures required for the recruitment and activity of the dengue virus polymerase (2011) J Biol Chem, 286, pp. 6929-6939. , 10.1074/jbc.M110.162289, 21183683: –
• Filomatori, C.V., Lodeiro, M.F., Alvarez, D.E., Samsa, M.M., Pietrasanta, L., A 5' RNA element promotes dengue virus RNA synthesis on a circular genome (2006) Genes Dev, 20, pp. 2238-2249. , 16882970,–
• Mazzon, M., Jones, M., Davidson, A., Chain, B., Jacobs, M., Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation (2009) J Infect Dis, 200, pp. 1261-1270. , 10.1086/605847, 19754307: –
• Ashour, J., Laurent-Rolle, M., Shi, P.Y., Garcia-Sastre, A., NS5 of dengue virus mediates STAT2 binding and degradation (2009) J Virol, 83, pp. 5408-5418. , 10.1128/JVI.02188-08, 19279106: –
• Morrison, J., Laurent-Rolle, M., Maestre, A.M., Rajsbaum, R., Pisanelli, G., Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling (2013) PLoS Pathog, 9, p. e1003265. , 10.1371/journal.ppat.1003265, 23555265
• Tay, M.Y., Fraser, J.E., Chan, W.K., Moreland, N.J., Rathore, A.P., Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin (2013) Antiviral Res, 99, pp. 301-306. , 10.1016/j.antiviral.2013.06.002, 23769930,–
• Kumar, A., Buhler, S., Selisko, B., Davidson, A., Mulder, K., Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signaling (2013) J Virol, 87, pp. 4545-4557. , 10.1128/JVI.03083-12, 23408610,–
• Hannemann, H., Sung, P.Y., Chiu, H.C., Yousuf, A., Bird, J., Serotype-specific differences in dengue virus non-structural protein 5 nuclear localization (2013) J Biol Chem, 288, pp. 22621-22635. , 10.1074/jbc.M113.481382, 23770669,–
• Pryor, M.J., Rawlinson, S.M., Butcher, R.E., Barton, C.L., Waterhouse, T.A., Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection (2007) Traffic, 8, pp. 795-807. , 17537211,–
• Brooks, A.J., Johansson, M., John, A.V., Xu, Y., Jans, D.A., The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin beta 1 and importin alpha/beta-recognized nuclear localization signals (2002) J Biol Chem, 277, pp. 36399-36407. , 12105224,–
• Will, C.L., Luhrmann, R., Spliceosome structure and function (2011) Cold Spring Harb Perspect Biol, 3
• Wahl, M.C., Will, C.L., Luhrmann, R., The spliceosome: design principles of a dynamic RNP machine (2009) Cell, 136, pp. 701-718. , 10.1016/j.cell.2009.02.009, 19239890: –
• Lad, S.P., Yang, G., Scott, D.A., Chao, T.H., Correia Jda, S., Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling (2008) Mol Immunol, 45, pp. 2277-2287. , 10.1016/j.molimm.2007.11.018, 18207245,–
• Zhu, C., Xiao, F., Hong, J., Wang, K., Liu, X., EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway (2015) J Virol, 89, pp. 6608-6618. , 10.1128/JVI.00364-15, 25878102,–
• Almstead, L.L., Sarnow, P., Inhibition of U snRNP assembly by a virus-encoded proteinase (2007) Genes Dev, 21, pp. 1086-1097. , 17473171: –
• Verschueren, E., Von Dollen, J., Cimermancic, P., Gulbahce, N., Sali, A., Scoring Large-Scale Affinity Purification Mass Spectrometry Datasets with MiST (2015) Curr Protoc Bioinformatics, 49, pp. 11-16
• Poyomtip, T., Hodge, K., Matangkasombut, P., Sakuntabhai, A., Pisitkun, T., Development of viable TAP-tagged dengue virus for investigation of host-virus interactions in viral replication (2016) J Gen Virol, 97, pp. 646-658. , 10.1099/jgv.0.000371, 26669909,–
• Girard, C., Will, C.L., Peng, J., Makarov, E.M., Kastner, B., Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion (2012) Nat Commun, 3, p. 994. , 10.1038/ncomms1998, 22871813
• Schreiber, C.A., Sakuma, T., Izumiya, Y., Holditch, S.J., Hickey, R.D., An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses (2015) PLoS Pathog, 11, p. e1005082. , 10.1371/journal.ppat.1005082, 26244496
• Lin, W., Zhu, C., Hong, J., Zhao, L., Jilg, N., The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing (2015) J Hepatol, 62, pp. 1024-1032. , 10.1016/j.jhep.2014.11.038, 25481564,–
• Zhao, H., Lin, W., Kumthip, K., Cheng, D., Fusco, D.N., A functional genomic screen reveals novel host genes that mediate interferon-alpha's effects against hepatitis C virus (2012) J Hepatol, 56, pp. 326-333. , 10.1016/j.jhep.2011.07.026, 21888876,–
• Sessions, O.M., Tan, Y., Goh, K.C., Liu, Y., Tan, P., Host cell transcriptome profile during wild-type and attenuated dengue virus infection (2013) PLoS Negl Trop Dis, 7, p. e2107. , 10.1371/journal.pntd.0002107, 23516652
• Koop, A., Lepenies, I., Braum, O., Davarnia, P., Scherer, G., Novel splice variants of human IKKepsilon negatively regulate IKKepsilon-induced IRF3 and NF-kB activation (2011) Eur J Immunol, 41, pp. 224-234. , 10.1002/eji.201040814, 21182093,–
• Ku, C.C., Che, X.B., Reichelt, M., Rajamani, J., Schaap-Nutt, A., Herpes simplex virus-1 induces expression of a novel MxA isoform that enhances viral replication (2011) Immunol Cell Biol, 89, pp. 173-182. , 10.1038/icb.2010.83, 20603636,–
• Smith, S.A., Lynch, K.W., Cell-based splicing of minigenes (2014) Methods Mol Biol, 1126, pp. 243-255. , 10.1007/978-1-62703-980-2_18, 24549669: –
• Zuccato, E., Buratti, E., Stuani, C., Baralle, F.E., Pagani, F., An intronic polypyrimidine-rich element downstream of the donor site modulates cystic fibrosis transmembrane conductance regulator exon 9 alternative splicing (2004) J Biol Chem, 279, pp. 16980-16988. , 14966131: –
• Massiello, A., Salas, A., Pinkerman, R.L., Roddy, P., Roesser, J.R., Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramide (2004) J Biol Chem, 279, pp. 15799-15804. , 14734550,–
• Caputi, M., Casari, G., Guenzi, S., Tagliabue, R., Sidoli, A., A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon (1994) Nucleic Acids Res, 22, pp. 1018-1022. , 8152907,–
• Cramer, P., Caceres, J.F., Cazalla, D., Kadener, S., Muro, A.F., Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer (1999) Mol Cell, 4, pp. 251-258. , 10488340,–
• Ranjith-Kumar, C.T., Gajewski, J., Gutshall, L., Maley, D., Sarisky, R.T., Terminal nucleotidyl transferase activity of recombinant Flaviviridae RNA-dependent RNA polymerases: implication for viral RNA synthesis (2001) J Virol, 75, pp. 8615-8623. , 11507207,–
• Dong, H., Chang, D.C., Hua, M.H., Lim, S.P., Chionh, Y.H., 2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase (2012) PLoS Pathog, 8, p. e1002642. , 10.1371/journal.ppat.1002642, 22496660
• Kroschewski, H., Lim, S.P., Butcher, R.E., Yap, T.L., Lescar, J., Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain (2008) J Biol Chem, 283, pp. 19410-19421. , 10.1074/jbc.M800613200, 18469001,–
• Zhou, Y., Ray, D., Zhao, Y., Dong, H., Ren, S., Structure and function of flavivirus NS5 methyltransferase (2007) J Virol, 81, pp. 3891-3903. , 17267492,–
• Alvarez, E., Castello, A., Carrasco, L., Izquierdo, J.M., Poliovirus 2A protease triggers a selective nucleo-cytoplasmic redistribution of splicing factors to regulate alternative pre-mRNA splicing (2013) PLoS One, 8, p. e73723. , 10.1371/journal.pone.0073723, 24066065:
• Fitzgerald, K.D., Semler, B.L., Poliovirus infection induces the co-localization of cellular protein SRp20 with TIA-1, a cytoplasmic stress granule protein (2013) Virus Res, 176, pp. 223-231. , 10.1016/j.virusres.2013.06.012, 23830997: –
• Sauterer, R.A., Feeney, R.J., Zieve, G.W., Cytoplasmic assembly of snRNP particles from stored proteins and newly transcribed snRNA's in L929 mouse fibroblasts (1988) Exp Cell Res, 176, pp. 344-359. , 2967772: –
• Makarova, O.V., Makarov, E.M., Luhrmann, R., The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes (2001) EMBO J, 20, pp. 2553-2563. , 11350945: –
• Zillmann, M., Zapp, M.L., Berget, S.M., Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles (1988) Mol Cell Biol, 8, pp. 814-821. , 2832738: –
• Dignam, J.D., Lebovitz, R.M., Roeder, R.G., Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei (1983) Nucleic Acids Res, 11, pp. 1475-1489. , 6828386: –
• Mancini, E., Sanchez, S.E., Romanowski, A., Schlaen, R.G., Sanchez-Lamas, M., Acute Effects of Light on Alternative Splicing in Light-Grown Plants (2016) Photochem Photobiol, 92, pp. 126-133. , 10.1111/php.12550, 26575044,–
• Braunschweig, U., Barbosa-Morais, N.L., Pan, Q., Nachman, E.N., Alipanahi, B., Widespread intron retention in mammals functionally tunes transcriptomes (2014) Genome Res, 24, pp. 1774-1786. , 10.1101/gr.177790.114, 25258385,–
• Samsa, M.M., Mondotte, J.A., Caramelo, J.J., Gamarnik, A.V., Uncoupling cis-Acting RNA elements from coding sequences revealed a requirement of the N-terminal region of dengue virus capsid protein in virus particle formation (2012) J Virol, 86, pp. 1046-1058. , 10.1128/JVI.05431-11, 22072762: –
• Chiu, H.C., Hannemann, H., Heesom, K.J., Matthews, D.A., Davidson, A.D., High-throughput quantitative proteomic analysis of dengue virus type 2 infected A549 cells (2014) PLoS One, 9, p. e93305. , 10.1371/journal.pone.0093305, 24671231:
• Khadka, S., Vangeloff, A.D., Zhang, C., Siddavatam, P., Heaton, N.S., A physical interaction network of dengue virus and human proteins (2011) Mol Cell Proteomics, 10, p. M111. , 012187
• Paranjape, S.M., Harris, E., Y box-binding protein-1 binds to the dengue virus 3'-untranslated region and mediates antiviral effects (2007) J Biol Chem, 282, pp. 30497-30508. , 17726010: –
• Eswaran, J., Horvath, A., Godbole, S., Reddy, S.D., Mudvari, P., RNA sequencing of cancer reveals novel splicing alterations (2013) Sci Rep, 3, p. 1689. , 10.1038/srep01689, 23604310
• Zhang, Q., Li, H., Jin, H., Tan, H., Zhang, J., The global landscape of intron retentions in lung adenocarcinoma (2014) BMC Med Genomics, 7, p. 15. , 10.1186/1755-8794-7-15, 24646369
• Lee, S.C., Dvinge, H., Kim, E., Cho, H., Micol, J.B., Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins (2016) Nat Med, 22, pp. 672-678. , 10.1038/nm.4097, 27135740,–
• Liu, Y.C., Kuo, R.L., Lin, J.Y., Huang, P.N., Huang, Y., Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8 (2014) PLoS Pathog, 10, p. e1004199. , 10.1371/journal.ppat.1004199, 24968230
• Corrionero, A., Minana, B., Valcarcel, J., Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A (2011) Genes Dev, 25, pp. 445-459. , 10.1101/gad.2014311, 21363963: –
• Papasaikas, P., Tejedor, J.R., Vigevani, L., Valcarcel, J., Functional splicing network reveals extensive regulatory potential of the core spliceosomal machinery (2015) Mol Cell, 57, pp. 7-22. , 10.1016/j.molcel.2014.10.030, 25482510: –
• Alvarez, D.E., De Lella Ezcurra, A.L., Fucito, S., Gamarnik, A.V., Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication (2005) Virology, 339, pp. 200-212. , 16002117: –
• Mondotte, J.A., Lozach, P.Y., Amara, A., Gamarnik, A.V., Essential role of dengue virus envelope protein N glycosylation at asparagine-67 during viral propagation (2007) J Virol, 81, pp. 7136-7148. , 17459925: –
• Oliphant, T., Engle, M., Nybakken, G.E., Doane, C., Johnson, S., Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus (2005) Nat Med, 11, pp. 522-530. , 15852016,–
• Samsa, M.M., Mondotte, J.A., Iglesias, N.G., Assuncao-Miranda, I., Barbosa-Lima, G., Dengue virus capsid protein usurps lipid droplets for viral particle formation (2009) PLoS Pathog, 5, p. e1000632. , 10.1371/journal.ppat.1000632, 19851456
• Szklarczyk, D., Franceschini, A., Wyder, S., Forslund, K., Heller, D., STRING v10: protein-protein interaction networks, integrated over the tree of life (2015) Nucleic Acids Res, 43, pp. D447-452. , 10.1093/nar/gku1003, 25352553,–
• Wysocka, J., Reilly, P.T., Herr, W., Loss of HCF-1-chromatin association precedes temperature-induced growth arrest of tsBN67 cells (2001) Mol Cell Biol, 21, pp. 3820-3829. , 11340173: –
• Pagani, F., Stuani, C., Zuccato, E., Kornblihtt, A.R., Baralle, F.E., Promoter architecture modulates CFTR exon 9 skipping (2003) J Biol Chem, 278, pp. 1511-1517. , 12421814: –
• Trapnell, C., Pachter, L., Salzberg, S.L., TopHat: discovering splice junctions with RNA-Seq (2009) Bioinformatics, 25, pp. 1105-1111. , 10.1093/bioinformatics/btp120, 19289445: –
• Robinson, M.D., McCarthy, D.J., Smyth, G.K., edgeR: a Bioconductor package for differential expression analysis of digital gene expression data (2010) Bioinformatics, 26, pp. 139-140. , 10.1093/bioinformatics/btp616, 19910308: –
• Jager, S., Cimermancic, P., Gulbahce, N., Johnson, J.R., McGovern, K.E., Global landscape of HIV-human protein complexes (2012) Nature, 481, pp. 365-370

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