Artículo
Rubinstein, M.; Low, M.J. "The smoking gun in nicotine-induced anorexia" (2011) Cell Metabolism. 14(2):145-147
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Abstract:
Hypothalamic pro-opiomelanocortin (POMC) neurons are the major source of anorectic melanocortin peptides in the brain. A recent study (Mineur et al., 2011) demonstrates that nicotine directly stimulates arcuate POMC neurons through nicotinic acetylcholinergic α3β4 receptors, suggesting a new mechanism to understand the inverse relationship between tobacco smoking and body weight. © 2011 Elsevier Inc.
Registro:
| Documento: | Artículo |
| Título: | The smoking gun in nicotine-induced anorexia |
| Autor: | Rubinstein, M.; Low, M.J. |
| Filiación: | Instituto de Investigaciones en Ingeniería Genética Y Biología Molecular, Consejo Nacional de Investigaciones Científicas Y Técnicas, Buenos Aires C1428ADN, Argentina Departamento de Fisiología, Biología Molecular Y Celular, Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, Buenos Aires C1428EGA, Argentina Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, United States Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, United States Brehm Center for Diabetes Research, University of Michigan, Ann Arbor, MI 48109, United States |
| Palabras clave: | acetylcholine; anorexigenic agent; nicotine; nicotinic receptor; nicotinic receptor alpha3beta4; proopiomelanocortin; unclassified drug; varenicline; anorexia; anxiety; body weight; caloric intake; cigarette smoking; food intake; human; hypothalamus; nerve cell; nonhuman; priority journal; short survey; smoking; smoking cessation; Nicotiana tabacum |
| Año: | 2011 |
| Volumen: | 14 |
| Número: | 2 |
| Página de inicio: | 145 |
| Página de fin: | 147 |
| DOI: | http://dx.doi.org/10.1016/j.cmet.2011.07.006 |
| Título revista: | Cell Metabolism |
| Título revista abreviado: | Cell Metab. |
| ISSN: | 15504131 |
| CAS: | acetylcholine, 51-84-3, 60-31-1, 66-23-9; nicotine, 54-11-5; proopiomelanocortin, 66796-54-1; varenicline, 249296-44-4, 375815-87-5 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15504131_v14_n2_p145_Rubinstein |
Referencias:
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- Cone, R.D., (2005) Nat. Neurosci., 8, pp. 571-578
- Cowley, M.A., Smart, J.L., Rubinstein, M., Cerdán, M.G., Diano, S., Horvath, T.L., Cone, R.D., Low, M.J., (2001) Nature, 411, pp. 480-484
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- Mihalak, K.B., Carroll, F.I., Luetje, C.W., (2006) Mol. Pharmacol., 70, pp. 801-805
- Mineur, Y.S., Abizaid, A., Rao, Y., Salas, R., DiLeone, R.J., Gündisch, D., Diano, S., Picciotto, M.R., (2011) Science, 332, pp. 1330-1332
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Citas:
---------- APA ----------
Rubinstein, M. & Low, M.J. (2011) . The smoking gun in nicotine-induced anorexia. Cell Metabolism, 14(2), 145-147.http://dx.doi.org/10.1016/j.cmet.2011.07.006
---------- CHICAGO ----------
Rubinstein, M., Low, M.J. "The smoking gun in nicotine-induced anorexia" . Cell Metabolism 14, no. 2 (2011) : 145-147.http://dx.doi.org/10.1016/j.cmet.2011.07.006
---------- MLA ----------
Rubinstein, M., Low, M.J. "The smoking gun in nicotine-induced anorexia" . Cell Metabolism, vol. 14, no. 2, 2011, pp. 145-147.http://dx.doi.org/10.1016/j.cmet.2011.07.006
---------- VANCOUVER ----------
Rubinstein, M., Low, M.J. The smoking gun in nicotine-induced anorexia. Cell Metab. 2011;14(2):145-147.http://dx.doi.org/10.1016/j.cmet.2011.07.006
