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Kornblihtt, A.R.; Schor, I.E.; Allo, M.; Blencowe, B.J. "When chromatin meets splicing" (2009) Nature Structural and Molecular Biology. 16(9):902-903
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Abstract:

Using bioinformatics analysis of previously published global genome deep-sequencing data, two papers now show that DNA sequences associated with nucleosomes are preferentially located in exons. The correlation between nucleosome distribution and the exon-intron organization of genes may have a key role in exon recognition at the pre-mRNA level during co-transcriptional splicing, consistent with previous findings indicating chromatin-mediated regulation of alternative splicing. © 2009 Nature America, Inc. All rights reserved.

Registro:

Documento: Artículo
Título:When chromatin meets splicing
Autor:Kornblihtt, A.R.; Schor, I.E.; Allo, M.; Blencowe, B.J.
Filiación:Departamento de Fisiología y Biología Molecular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada
Palabras clave:alternative RNA splicing; bioinformatics; chromatin; DNA sequence; exon; genome; genome analysis; human; intron; molecular recognition; nonhuman; nucleosome; priority journal; regulatory mechanism; short survey; Alternative Splicing; Animals; Base Composition; Chromatin; Exons; Humans; Introns; RNA Precursors; Transcription, Genetic
Año:2009
Volumen:16
Número:9
Página de inicio:902
Página de fin:903
DOI: http://dx.doi.org/10.1038/nsmb0909-902
Título revista:Nature Structural and Molecular Biology
Título revista abreviado:Nat. Struct. Mol. Biol.
ISSN:15459993
CODEN:NSMBC
CAS:Chromatin; RNA Precursors
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15459993_v16_n9_p902_Kornblihtt

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Citas:

---------- APA ----------
Kornblihtt, A.R., Schor, I.E., Allo, M. & Blencowe, B.J. (2009) . When chromatin meets splicing. Nature Structural and Molecular Biology, 16(9), 902-903.
http://dx.doi.org/10.1038/nsmb0909-902
---------- CHICAGO ----------
Kornblihtt, A.R., Schor, I.E., Allo, M., Blencowe, B.J. "When chromatin meets splicing" . Nature Structural and Molecular Biology 16, no. 9 (2009) : 902-903.
http://dx.doi.org/10.1038/nsmb0909-902
---------- MLA ----------
Kornblihtt, A.R., Schor, I.E., Allo, M., Blencowe, B.J. "When chromatin meets splicing" . Nature Structural and Molecular Biology, vol. 16, no. 9, 2009, pp. 902-903.
http://dx.doi.org/10.1038/nsmb0909-902
---------- VANCOUVER ----------
Kornblihtt, A.R., Schor, I.E., Allo, M., Blencowe, B.J. When chromatin meets splicing. Nat. Struct. Mol. Biol. 2009;16(9):902-903.
http://dx.doi.org/10.1038/nsmb0909-902