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Abstract:

A recent study reveals that the chromatin-remodeling factor SWI/SNF regulates alternative splicing by creating internal 'roadblocks' to transcriptional elongation where the phosphorylation status of RNA pol II is qualitatively changed. © 2006 Nature Publishing Group.

Registro:

Documento: Artículo
Título:Chromatin, transcript elongation and alternative splicing
Autor:Kornblihtt, A.R.
Filiación:Departamento de Fisiología Y Biología Molecular, LFBM and IFIByNE-CONICET, Pabellón 2, (C1428EHA) Buenos Aires, Argentina
Palabras clave:DNA directed RNA polymerase; protein SWI; RNA polymerase II; alternative RNA splicing; chromatin; chromatin assembly and disassembly; genetic transcription; human; phosphorylation; priority journal; protein function; regulatory RNA sequence; short survey; transcription regulation; Alternative Splicing; Animals; Chromatin; Humans; Kinetics; RNA Polymerase II; Transcription Factors; Transcription, Genetic
Año:2006
Volumen:13
Número:1
Página de inicio:5
Página de fin:7
DOI: http://dx.doi.org/10.1038/nsmb0106-5
Título revista:Nature Structural and Molecular Biology
Título revista abreviado:Nat. Struct. Mol. Biol.
ISSN:15459993
CODEN:NSMBC
CAS:Chromatin; RNA Polymerase II, EC 2.7.7.-; SMARCA2 protein, human; Transcription Factors
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15459993_v13_n1_p5_Kornblihtt

Referencias:

  • Roberts, G.C., Gooding, C., Mak, H.Y., Proudfoot, N.J., Smith, C.W.J., (1998) Nucleic Acids Res., 26, pp. 5568-5572
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  • Cramer, P., Pesce, C.G., Baralle, F.E., Kornblihtt, A.R., (1997) Proc. Natl. Acad. Sci. USA, 94, pp. 11456-11460
  • Kornblihtt, A.R., (2005) Curr. Opin. Cell Biol., 17, pp. 262-268
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Citas:

---------- APA ----------
(2006) . Chromatin, transcript elongation and alternative splicing. Nature Structural and Molecular Biology, 13(1), 5-7.
http://dx.doi.org/10.1038/nsmb0106-5
---------- CHICAGO ----------
Kornblihtt, A.R. "Chromatin, transcript elongation and alternative splicing" . Nature Structural and Molecular Biology 13, no. 1 (2006) : 5-7.
http://dx.doi.org/10.1038/nsmb0106-5
---------- MLA ----------
Kornblihtt, A.R. "Chromatin, transcript elongation and alternative splicing" . Nature Structural and Molecular Biology, vol. 13, no. 1, 2006, pp. 5-7.
http://dx.doi.org/10.1038/nsmb0106-5
---------- VANCOUVER ----------
Kornblihtt, A.R. Chromatin, transcript elongation and alternative splicing. Nat. Struct. Mol. Biol. 2006;13(1):5-7.
http://dx.doi.org/10.1038/nsmb0106-5