We present a simple model that displays all classes of two-dimensional excitable regimes. One of the variables of the model displays the usual spikes observed in excitable systems. Since the model is written in terms of a "standard" vector field, it is always possible to fit it to experimental data displaying spikes in an algorithmic way. In fact, we use it to fit a series of membrane potential recordings obtained in the medicinal leech and time series generated with the FitzHugh-Nagumo equations and the excitability model of Eguía et al. [Phys. Rev. E 58, 2636 (1998)]. In each case, we determine the excitability class of the corresponding system.
Documento: | Artículo |
Título: | Generic two-variable model of excitability |
Autor: | Ventura, A.C.; Mindlin, G.B.; Dawson, S.P. |
Filiación: | Departamento de Física, FCEN, UBA Ciudad Universitaria, Pabellón I (1428), Buenos Aires, Argentina |
Palabras clave: | animal; biological model; leech; membrane potential; physiology; signal transduction; Animals; Leeches; Membrane Potentials; Models, Neurological; Signal Transduction |
Año: | 2002 |
Volumen: | 65 |
Número: | 4 |
Página de inicio: | 46231 |
Título revista: | Physical review. E, Statistical, nonlinear, and soft matter physics |
Título revista abreviado: | Phys Rev E Stat Nonlin Soft Matter Phys |
ISSN: | 15393755 |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15393755_v65_n4_p46231_Ventura |