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Abstract:

Hydrogen peroxide (H2O2) is a naturally occurring prooxidant molecule, and its effects in the macroinvertebrate infauna were previously observed. The existence of a gradient of antioxidant enzymes activity (catalase [CAT], glutathione peroxidase [GPx], superoxide dismutase [SOD], and glutathione-S-transferase [GST]) and/or oxidative damage along the body of the estuarine polychaeta Laeonereis acuta (Polychaeta, Nereididae) was analyzed after exposure to H2O2. Because this species secretes conspicuous amounts of mucus, its capability in degrading H2O 2 was studied. The results suggest that L. acuta deal with the generation of oxidative stress with different strategies along the body. In the posterior region, higher CAT and SOD activities ensure the degradation of inductors of lipid peroxidation such as H2O2 and superoxide anion (O2•-). The higher GST activity in anterior region aids to conjugate lipid peroxides products. In the middle region, the lack of high CAT, SOD, or GST activities correlates with the higher lipid hydroperoxide levels found after H2O2 exposure. Ten days of exposure to H2O2 also induced oxidative stress (lipid peroxidation and DNA damage) in the whole animal paralleled by a lack of CAT induction. The mucus production contributes substantially to H 2O2 degradation, suggesting that bacteria that grow in this secretion provide this capability. © 2005 by The University of Chicago. All rights reserved.

Registro:

Documento: Artículo
Título:Antioxidant mechanisms of the nereidid Laeonereis acuta (Anelida: Polychaeta) to cope with environmental hydrogen peroxide
Autor:Da Rosa, C.E.; Iurman, M.G.; Abreu, P.C.; Geracitano, L.A.; Monserrat, J.M.
Filiación:Departamento de Ciências Fisiológicas, Fundação Universidade Federal do Rio Grande, Avenida Itália, Km 8, Rio Grande, Rio Grande do Sul, Brazil
Programa de Pos-Graduacao em Ciencias Fisiologicas-Fisiologia Animal Comparada, Departamento de Ciências Fisiológicas, Fundaçâo Universidade Federal do Rio Grande, Brazil
Laboratorio de Histología Animal, Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Departamento de Oceanografia, Fundação Universidade Federal do Rio Grande, Brazil
Programa de Pós-Graduação em Oceanografia Biológica, Fundação Universidade Federal do Rio Grande, Brazil
Palabras clave:catalase; glutathione peroxidase; glutathione transferase; hydrogen peroxide; superoxide dismutase; antioxidant; adaptation; analysis of variance; animal; article; comet assay; comparative study; DNA damage; enzymology; metabolism; mucus; oxidative stress; physiology; Polychaeta; time; Adaptation, Physiological; Analysis of Variance; Animals; Catalase; Comet Assay; DNA Damage; Glutathione Peroxidase; Glutathione Transferase; Hydrogen Peroxide; Mucus; Oxidative Stress; Polychaeta; Superoxide Dismutase; Time Factors; Animalia; Laeonereis acuta; Nereididae; Polychaeta
Año:2005
Volumen:78
Número:4
Página de inicio:641
Página de fin:649
DOI: http://dx.doi.org/10.1086/430229
Título revista:Physiological and Biochemical Zoology
Título revista abreviado:Physiol. Biochem. Zool.
ISSN:15222152
CODEN:PBZOF
CAS:catalase, 9001-05-2; glutathione peroxidase, 9013-66-5; glutathione transferase, 50812-37-8; hydrogen peroxide, 7722-84-1; superoxide dismutase, 37294-21-6, 9016-01-7, 9054-89-1; Catalase, EC 1.11.1.6; Glutathione Peroxidase, EC 1.11.1.9; Glutathione Transferase, EC 2.5.1.18; Hydrogen Peroxide, 7722-84-1; Superoxide Dismutase, EC 1.15.1.1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15222152_v78_n4_p641_DaRosa

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Citas:

---------- APA ----------
Da Rosa, C.E., Iurman, M.G., Abreu, P.C., Geracitano, L.A. & Monserrat, J.M. (2005) . Antioxidant mechanisms of the nereidid Laeonereis acuta (Anelida: Polychaeta) to cope with environmental hydrogen peroxide. Physiological and Biochemical Zoology, 78(4), 641-649.
http://dx.doi.org/10.1086/430229
---------- CHICAGO ----------
Da Rosa, C.E., Iurman, M.G., Abreu, P.C., Geracitano, L.A., Monserrat, J.M. "Antioxidant mechanisms of the nereidid Laeonereis acuta (Anelida: Polychaeta) to cope with environmental hydrogen peroxide" . Physiological and Biochemical Zoology 78, no. 4 (2005) : 641-649.
http://dx.doi.org/10.1086/430229
---------- MLA ----------
Da Rosa, C.E., Iurman, M.G., Abreu, P.C., Geracitano, L.A., Monserrat, J.M. "Antioxidant mechanisms of the nereidid Laeonereis acuta (Anelida: Polychaeta) to cope with environmental hydrogen peroxide" . Physiological and Biochemical Zoology, vol. 78, no. 4, 2005, pp. 641-649.
http://dx.doi.org/10.1086/430229
---------- VANCOUVER ----------
Da Rosa, C.E., Iurman, M.G., Abreu, P.C., Geracitano, L.A., Monserrat, J.M. Antioxidant mechanisms of the nereidid Laeonereis acuta (Anelida: Polychaeta) to cope with environmental hydrogen peroxide. Physiol. Biochem. Zool. 2005;78(4):641-649.
http://dx.doi.org/10.1086/430229