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Abstract:

As part of the development of an analytical technique for the detection of meridianins and related compounds in biological fluids, a crude extract of the tunicate Aplidium meridianum was analysed using neutral loss tandem mass spectrometry. The 41 u neutral loss-EI(+) mass spectrum showed molecular ions corresponding to two previously undetected alkaloids. We report herein the isolation and structure elucidation of these alkaloids, meridianins F and G.

Registro:

Documento: Artículo
Título:Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy
Autor:Seldes, A.M.; Brasco, M.F.R.; Franco, L.H.; Palermo, J.A.
Filiación:Facultad de Ciencias Exactas y Naturales, Departamento de Quimica Organica, Universidad de Buenos Aires, Buenos Aires, Argentina
Palabras clave:Constant neutral loss; Indole alkaloids; Marine natural products; Meridianins; Tandem mass spectrometry; alkaloid derivative; meridianin F; meridianin g; unclassified drug; article; controlled study; drug identification; drug isolation; drug structure; electrospray mass spectrometry; infrared spectrophotometry; marine species; nonhuman; proton nuclear magnetic resonance; tandem mass spectrometry; ultraviolet spectrophotometry; Alkaloids; Animals; Indole Alkaloids; Molecular Structure; Tandem Mass Spectrometry; Urochordata; Aplidium meridianum
Año:2007
Volumen:21
Número:6
Página de inicio:555
Página de fin:563
DOI: http://dx.doi.org/10.1080/14786410601133517
Título revista:Natural Product Research
Título revista abreviado:Nat. Prod. Res.
ISSN:14786419
CODEN:NPRAA
CAS:Alkaloids; Indole Alkaloids; meridianin F; meridianin G
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14786419_v21_n6_p555_Seldes

Referencias:

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Citas:

---------- APA ----------
Seldes, A.M., Brasco, M.F.R., Franco, L.H. & Palermo, J.A. (2007) . Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy. Natural Product Research, 21(6), 555-563.
http://dx.doi.org/10.1080/14786410601133517
---------- CHICAGO ----------
Seldes, A.M., Brasco, M.F.R., Franco, L.H., Palermo, J.A. "Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy" . Natural Product Research 21, no. 6 (2007) : 555-563.
http://dx.doi.org/10.1080/14786410601133517
---------- MLA ----------
Seldes, A.M., Brasco, M.F.R., Franco, L.H., Palermo, J.A. "Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy" . Natural Product Research, vol. 21, no. 6, 2007, pp. 555-563.
http://dx.doi.org/10.1080/14786410601133517
---------- VANCOUVER ----------
Seldes, A.M., Brasco, M.F.R., Franco, L.H., Palermo, J.A. Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy. Nat. Prod. Res. 2007;21(6):555-563.
http://dx.doi.org/10.1080/14786410601133517