Artículo

Zeug, A.; Zimmermann, J.; Röder, B.; Lagorio, M.G.; San Román, E. "Microcrystalline cellulose as a carrier for hydrophobic photosensitizers in water" (2002) Photochemical and Photobiological Sciences. 1(3):198-203
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Abstract:

Samples of pheophorbide-a adsorbed on microcrystalline cellulose, which have been previously characterized in the solid state (M.G. Lagorio, E. San Roman, A. Zcug, J. Zimmermann and B. Röder, Phys. Chem. Chem. Phys., 2001, 3, 1524 1529), were washed with water, leading to stable suspensions of ultrafinc particles (d < 2 μm) carrying photoactive, monomeric dye molecules. Detachment can be controlled through the particle size distribution. Suspensions are fluorescent and generate singlet molecular oxygen efficiently. A similar effect has been observed on washing samples containing hematoporphyrin IX adsorbed on the same support. Thus, using cellulose as a heterogeneous carrier, it is possible to introduce hydrophobic photosensitizers into the aqueous medium while avoiding aggregation, thus preserving their photophysical properties. At the same time, the spectroscopic properties of dyes attached to cellulose particles are compared with those in ethanol and ethanol-water mixtures and their differences are explained in terms of medium polarity and dye aggregation.

Registro:

Documento: Artículo
Título:Microcrystalline cellulose as a carrier for hydrophobic photosensitizers in water
Autor:Zeug, A.; Zimmermann, J.; Röder, B.; Lagorio, M.G.; San Román, E.
Filiación:Humboldt-Universität, Institut für Physik, Lehrstuhl für Photobiophysik, Invalidenstraße 110, 10115 Berlin, Germany
INQUIMAE/DQIAyQF, Facultad Ciencias Exactas Naturales, Universidad de Buenos Aires, Pabellón II, C1428EHA Buenos Aires, Argentina
University of California, Department of Chemistry, Fleming Research Group, B84 Hildebrand Hall, Berkeley, CA 94720-1460, United States
Palabras clave:alcohol; drug carrier; hematoporphyrin; microcrystalline cellulose; monomer; pheophorbide; photosensitizing agent; singlet oxygen; water; adsorption; aqueous solution; article; chemical binding; controlled study; fluorescence; hydrophobicity; particle size; priority journal; solid state; suspension; Roman
Año:2002
Volumen:1
Número:3
Página de inicio:198
Página de fin:203
DOI: http://dx.doi.org/10.1039/b109592g
Título revista:Photochemical and Photobiological Sciences
Título revista abreviado:Photochem. Photobiol. Sci.
ISSN:1474905X
CODEN:PPSHC
CAS:alcohol, 64-17-5; hematoporphyrin, 14459-29-1; microcrystalline cellulose, 39394-43-9, 51395-75-6; water, 7732-18-5
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1474905X_v1_n3_p198_Zeug

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Citas:

---------- APA ----------
Zeug, A., Zimmermann, J., Röder, B., Lagorio, M.G. & San Román, E. (2002) . Microcrystalline cellulose as a carrier for hydrophobic photosensitizers in water. Photochemical and Photobiological Sciences, 1(3), 198-203.
http://dx.doi.org/10.1039/b109592g
---------- CHICAGO ----------
Zeug, A., Zimmermann, J., Röder, B., Lagorio, M.G., San Román, E. "Microcrystalline cellulose as a carrier for hydrophobic photosensitizers in water" . Photochemical and Photobiological Sciences 1, no. 3 (2002) : 198-203.
http://dx.doi.org/10.1039/b109592g
---------- MLA ----------
Zeug, A., Zimmermann, J., Röder, B., Lagorio, M.G., San Román, E. "Microcrystalline cellulose as a carrier for hydrophobic photosensitizers in water" . Photochemical and Photobiological Sciences, vol. 1, no. 3, 2002, pp. 198-203.
http://dx.doi.org/10.1039/b109592g
---------- VANCOUVER ----------
Zeug, A., Zimmermann, J., Röder, B., Lagorio, M.G., San Román, E. Microcrystalline cellulose as a carrier for hydrophobic photosensitizers in water. Photochem. Photobiol. Sci. 2002;1(3):198-203.
http://dx.doi.org/10.1039/b109592g