Artículo
Nicoletti, D.; Ghini, A.A.; Brachet-Cota, A.L.; Burton, G. "Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione" (1995) Journal of the Chemical Society, Perkin Transactions 1(9):1089-1093
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Abstract:
A two-step synthesis of 19-functionalized 6-oxapregnanes from a 5α,6β-dihydroxypregnane is described. Deoxygenation at C-19 afforded a 6-oxapregnane, which was converted into 6-oxa-5β-pregnane-3,20-dione 7. An insight into the mechanism of formation of the key intermediate, a 5,6-secosteroid, via a hypoiodite type reaction is also given.
Registro:
| Documento: | Artículo |
| Título: | Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione |
| Autor: | Nicoletti, D.; Ghini, A.A.; Brachet-Cota, A.L.; Burton, G. |
| Filiación: | Departamento de Química Orgánica, Universidad de Buenos Aires, Ciudad Universitaria, (1428) Buenos Aires, Argentina |
| Año: | 1995 |
| Número: | 9 |
| Página de inicio: | 1089 |
| Página de fin: | 1093 |
| Título revista: | Journal of the Chemical Society, Perkin Transactions 1 |
| ISSN: | 14727781 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14727781_v_n9_p1089_Nicoletti |
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Citas:
---------- APA ----------
Nicoletti, D., Ghini, A.A., Brachet-Cota, A.L. & Burton, G. (1995) . Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione. Journal of the Chemical Society, Perkin Transactions 1(9), 1089-1093.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14727781_v_n9_p1089_Nicoletti [ ]
---------- CHICAGO ----------
Nicoletti, D., Ghini, A.A., Brachet-Cota, A.L., Burton, G. "Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione" . Journal of the Chemical Society, Perkin Transactions 1, no. 9 (1995) : 1089-1093.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14727781_v_n9_p1089_Nicoletti [ ]
---------- MLA ----------
Nicoletti, D., Ghini, A.A., Brachet-Cota, A.L., Burton, G. "Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione" . Journal of the Chemical Society, Perkin Transactions 1, no. 9, 1995, pp. 1089-1093.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14727781_v_n9_p1089_Nicoletti [ ]
---------- VANCOUVER ----------
Nicoletti, D., Ghini, A.A., Brachet-Cota, A.L., Burton, G. Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione. 1995(9):1089-1093.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14727781_v_n9_p1089_Nicoletti [ ]
