Abstract:
The thermal efficiency of the kinesin cycle at stalling is presently a matter of some debate, with published predictions ranging from 0 [Phys. Rev. Lett. 99, 158102 (2007); Phys. Rev. E 78, 011915 (2008)] to 100% [in Molecular Motors, edited by M. Schliwa (Wiley-VCH Verlag GmbH, Weinheim (2003), p. 207]. In this note we attemp to clarify the issues involved. We also find an upper bound on the kinesin efficiency by constructing an ideal kinesin cycle to which the real cycle may be compared. The ideal cycle has a thermal efficiency of less than one, and the real one is less efficient than the ideal one always, in compliance with Carnot's theorem. © 2009 EDP Sciences, SIF, Springer-Verlag Berlin Heidelberg.
Referencias:
- Schrodinger, E., (1945) What is Life? The Physical Aspect of the Living Cell, , Cambridge University Press, Cambridge
- Darling, D., (2001) Life Everywhere, , Basic Books, New York
- Nelson, P., (2004) Biological Physics, , Freeman, New York
- Tuszynski, J., Kurzynski, M., (2003) Introduction to molecular biophysics, , CRC Press, Boca Raton
- Haynes, D., (2008) Biological Thermodynamics, , Cambridge University Press, Cambridge
- F. Ritort, e-print arXiv: 0705.0455 (Adv. Chem. Phys. 137, to appear); Lau, A.W.C., Lacoste, D., Mallick, K., (2007) Phys. Rev. Lett, 99, p. 158102
- Lacoste, D., Lau, A.W.C., Mallick, K., (2008) Phys. Rev. E, 78, p. 011915
- Oster, G., Wang, H., How protein motors convert chemical energy into mechanical work (2003) Molecular Motors, p. 207. , edited by M. Schliwa Wiley-VCH Verlag GmbH, Weinheim
- Linke, H., Downton, M., Zuckerman, M., (2005) Chaos, 15, p. 026111
- Parrondo, J., Blanco, J., Cao, F., Brito, R., (1998) EuroPhys. Lett, 43, p. 248
- Parrondo, J., Jimenez de Cisneros, B., Brito, R., Thermodynamics of isothermal Brownian motors (2000) Stochastic Processes in Physics, Chemistry and Biology LNP557, p. 38. , edited by J. Freund, T. Poschel Springer-Verlag, Berlin
- Wang, H., Zhou, H., (2008) Stokes Efficiency of molecular motor-cargo systems, Abstract and Applied Analysis, p. 241736. , Article Id
- Magnasco, M., (1994) Phys. Rev. Lett, 72, p. 2656
- Ciudad, A., Sancho, J.M., Tsironis, G.P., (2006) J. Biol. Phys, 32, p. 455463
- M. Bier, Eur. Phys. J. B e2008-00271-1 (2008); Nishiyama, M., Higuchi, H., Ishii, Y., Taniguchi, Y., Yanagida, T., (2003) BioSystems, 71, p. 145
- Taniguchi, Y., Nishiyama, M., Ishii, Y., Yanagida, T., (2005) Nature Chemical Biology, 1. , 142
- Carter, N., Cross, R., (2005) Nature, 435, p. 308
- Schnitzer, M., Visscher, K., Block, S., (2000) Nature Cell Biology, 2, p. 718
- Howard, J., Mechanics of Motor Proteins (2002) Physics of Bio-molecules and cells 75th Les Houches Summer School, , edited by H. Flyvbjerg, F. Jülicher, P. Ormos, F. David Springer-Verlag, Berlin
- Rice, S., Cui, Y., Sindelar, C., Naber, N., Matuska, M., Vale, R., Cooke, R., (2003) Biophysical Journal, 84, p. 1844
- Block, S., Kinesin motor mechanics, , www.biophysics.org/discussions/2006/Block.pdf
- Crooks, G., (1998) J. Stat. Phys, 90, p. 1481
- Crooks, G., (1999) Phys. Rev. E, 60, p. 2721
- Crooks, G., (2000) Phys. Rev. E, 61, p. 2361
- Ritort, F., (2003) Poincare Seminar, 2, p. 195
- Collin, D., Ritort, F., Jarzynski, C., Smith, S., Tinoco Jr., I., Bustamante, C., (2005) Nature, 437, p. 231
- Kurchan, J., Non-equilibrium work relations, , e-print arXiv: cond-mat/0511073
- Maes, C., (2003) Seminaire Poincare, 2, p. 29
- F. Zamponi, F. Bonetto, L. Cugliandolo, J. Kurchan, J. Stat. Mech. P09013 (2005); O. Braun, A. Hanke, U. Seifert, energy landscapes by periodic loading, e-print arXiv: cond-mat/0402496; Braun, O., Seifert, U., (2004) Europhys. Lett, 68, p. 746752
Citas:
---------- APA ----------
(2009)
. Kinesin and the crooks fluctuation theorem. European Physical Journal B, 68(4), 601-605.
http://dx.doi.org/10.1140/epjb/e2009-00113-8---------- CHICAGO ----------
Calzetta, E.A.
"Kinesin and the crooks fluctuation theorem"
. European Physical Journal B 68, no. 4
(2009) : 601-605.
http://dx.doi.org/10.1140/epjb/e2009-00113-8---------- MLA ----------
Calzetta, E.A.
"Kinesin and the crooks fluctuation theorem"
. European Physical Journal B, vol. 68, no. 4, 2009, pp. 601-605.
http://dx.doi.org/10.1140/epjb/e2009-00113-8---------- VANCOUVER ----------
Calzetta, E.A. Kinesin and the crooks fluctuation theorem. Eur. Phys. J. B. 2009;68(4):601-605.
http://dx.doi.org/10.1140/epjb/e2009-00113-8