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Abstract:

An efficient route for large-scale preparation of lapyrium chloride, a broad-spectrum antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them enzymatic. Due to the chemoselective behavior of the biocatalysts, lapyrium chloride was obtained in a high degree of purity and yield, from mild reaction conditions and following a low environmental impact methodology. © Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

Registro:

Documento: Artículo
Título:An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
Autor:Rustoy, E.M.; Baldessari, A.
Filiación:Departamento de Química Orgánica Y UMYMFOR, Facultad de Ciencias Exactas Y Naturales, Pabellón 2, 1428 Buenos Aires, Argentina
Palabras clave:Aminolysis; Bactericide; Enzyme-catalyzed acylation
Año:2005
Número:21
Página de inicio:4628
Página de fin:4632
DOI: http://dx.doi.org/10.1002/ejoc.200500388
Título revista:European Journal of Organic Chemistry
Título revista abreviado:Eur. J. Org. Chem.
ISSN:1434193X
CODEN:EJOCF
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1434193X_v_n21_p4628_Rustoy

Referencias:

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Citas:

---------- APA ----------
Rustoy, E.M. & Baldessari, A. (2005) . An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride. European Journal of Organic Chemistry(21), 4628-4632.
http://dx.doi.org/10.1002/ejoc.200500388
---------- CHICAGO ----------
Rustoy, E.M., Baldessari, A. "An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride" . European Journal of Organic Chemistry, no. 21 (2005) : 4628-4632.
http://dx.doi.org/10.1002/ejoc.200500388
---------- MLA ----------
Rustoy, E.M., Baldessari, A. "An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride" . European Journal of Organic Chemistry, no. 21, 2005, pp. 4628-4632.
http://dx.doi.org/10.1002/ejoc.200500388
---------- VANCOUVER ----------
Rustoy, E.M., Baldessari, A. An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride. Eur. J. Org. Chem. 2005(21):4628-4632.
http://dx.doi.org/10.1002/ejoc.200500388