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Abstract:

This paper reports a synthesis of novel diheteroarylethenes functionalized for coupling to biomolecules starting from indole derivatives. The strategy is based on the derivatization at the N-atom in the indole substructure. TBDMS protection proved to be superior over BOC protection schemes, leading to higher yields in the overall synthesis. The suitability of the new derivatives as acceptors for pcFRET was calculated for selected donors.

Registro:

Documento: Artículo
Título:Synthesis of indole-containing diheteroarylethenes. New probes for photochromic FRET (pcFRET)
Autor:Giordano, L.; Vermeij, R.J.; Jares-Erijman, E.A.
Filiación:Departamento de Química Orgánica, Facultad de Ciencias Exactas Y Naturales, Ciudad Universitaria Pabellón II Buenos Aires, Argentina
Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany
Palabras clave:Diheteroarylethenes; FRET; Indole derivatives; Photochromism; Synthesis
Año:2006
Volumen:2005
Número:12
Página de inicio:268
Página de fin:281
Título revista:Arkivoc
Título revista abreviado:Arkivoc
ISSN:14246376
PDF:https://bibliotecadigital.exactas.uba.ar/download/paper/paper_14246376_v2005_n12_p268_Giordano.pdf
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p268_Giordano

Referencias:

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  • Giordano, L., Jovin, T.M., Irie, M., Jares-Erijman, E.A., (2002) J. Am. Chem. Soc., 124, p. 7481
  • Jares-Erijman, E.A., Jovin, T.M., (2003) Nat. Biotechnol., 21, p. 1387
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Citas:

---------- APA ----------
Giordano, L., Vermeij, R.J. & Jares-Erijman, E.A. (2006) . Synthesis of indole-containing diheteroarylethenes. New probes for photochromic FRET (pcFRET). Arkivoc, 2005(12), 268-281.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p268_Giordano [ ]
---------- CHICAGO ----------
Giordano, L., Vermeij, R.J., Jares-Erijman, E.A. "Synthesis of indole-containing diheteroarylethenes. New probes for photochromic FRET (pcFRET)" . Arkivoc 2005, no. 12 (2006) : 268-281.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p268_Giordano [ ]
---------- MLA ----------
Giordano, L., Vermeij, R.J., Jares-Erijman, E.A. "Synthesis of indole-containing diheteroarylethenes. New probes for photochromic FRET (pcFRET)" . Arkivoc, vol. 2005, no. 12, 2006, pp. 268-281.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p268_Giordano [ ]
---------- VANCOUVER ----------
Giordano, L., Vermeij, R.J., Jares-Erijman, E.A. Synthesis of indole-containing diheteroarylethenes. New probes for photochromic FRET (pcFRET). Arkivoc. 2006;2005(12):268-281.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p268_Giordano [ ]