Abstract:
(+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl] -6-chloropurine (compound 7) as an advanced synthetic intermediate. ©ARKAT.
Registro:
Documento: |
Artículo
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Título: | First total synthesis of (+)-Neplanocin B |
Autor: | Comin, M.J.; Pellegrinet, S.C.; Rodriguez, J.B. |
Filiación: | Departamento de Química Orgánica, Facultad de Ciencias Exactas Y Naturales, Ciudad Universitaria, C1428EHA, Buenos Aires, Argentina Instituto de Química Orgánica Y de Síntesis (CONICET), Facultad de Ciencias Bioquímicas Y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario S2002LRK, Argentina
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Palabras clave: | 6-oxabicyclo[3.1.0]hexane; Ampullariella regularis; Carbocyclic nucleosides; Conformationally locked nucleosides; Neplanocin B |
Año: | 2005
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Volumen: | 2005
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Número: | 12
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Página de inicio: | 205
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Página de fin: | 213
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Título revista: | Arkivoc
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Título revista abreviado: | Arkivoc
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ISSN: | 14246376
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PDF: | https://bibliotecadigital.exactas.uba.ar/download/paper/paper_14246376_v2005_n12_p205_Comin.pdf |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p205_Comin |
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Citas:
---------- APA ----------
Comin, M.J., Pellegrinet, S.C. & Rodriguez, J.B.
(2005)
. First total synthesis of (+)-Neplanocin B. Arkivoc, 2005(12), 205-213.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p205_Comin [ ]
---------- CHICAGO ----------
Comin, M.J., Pellegrinet, S.C., Rodriguez, J.B.
"First total synthesis of (+)-Neplanocin B"
. Arkivoc 2005, no. 12
(2005) : 205-213.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p205_Comin [ ]
---------- MLA ----------
Comin, M.J., Pellegrinet, S.C., Rodriguez, J.B.
"First total synthesis of (+)-Neplanocin B"
. Arkivoc, vol. 2005, no. 12, 2005, pp. 205-213.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p205_Comin [ ]
---------- VANCOUVER ----------
Comin, M.J., Pellegrinet, S.C., Rodriguez, J.B. First total synthesis of (+)-Neplanocin B. Arkivoc. 2005;2005(12):205-213.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14246376_v2005_n12_p205_Comin [ ]