We have described a method for preparation of [10B]-enriched-8- dihydroxyborylharmine (III) and characterized it by their spectral properties (MS, IR and NMR). This compound is a potential BNCT agent.
Documento: | Artículo |
Título: | A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy |
Autor: | Sintas, J.A.; Macareno, N.J.; Vitale, A.A. |
Filiación: | Departamento de Quimica Organica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina |
Palabras clave: | 8 dihydroxyborylharmine b 10; radiopharmaceutical agent; unclassified drug; animal tissue; autoradiography; binding site; conference paper; drug distribution; drug structure; drug synthesis; neutron capture therapy; nonhuman; rat |
Año: | 2000 |
Volumen: | 5 |
Número: | 3 |
Página de inicio: | 526 |
Página de fin: | 528 |
DOI: | http://dx.doi.org/10.3390/50300526 |
Título revista: | Molecules |
Título revista abreviado: | Molecules |
ISSN: | 14203049 |
CODEN: | MOLEF |
PDF: | https://bibliotecadigital.exactas.uba.ar/download/paper/paper_14203049_v5_n3_p526_Sintas.pdf |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14203049_v5_n3_p526_Sintas |