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Abstract:

In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1•s-1) was larger than that of Gd(DTPA)2-(R1 = 3.9 Mmol- 1•s-1). The results showed that the non-ion complex is a prospective MRI contrast agent. © 2014 Elsevier B.V. All rights reserved.

Registro:

Documento: Artículo
Título:Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
Autor:Martínez, M.D.; Rustoy, E.M.; Raggio, N.; Burton, G.
Filiación:CONICET-Universidad de Buenos Aires, Departamento de Química Orgánica, Ciudad Universitaria, Ciudad Autónoma de Buenos Aires, 1428, Argentina
Palabras clave:Contrast agent; Gadolinium; Macrocycle; Magnetic resonance imaging; Relaxivity
Año:2015
Volumen:51
Página de inicio:110
Página de fin:113
DOI: http://dx.doi.org/10.1016/j.inoche.2014.11.019
Título revista:Inorganic Chemistry Communications
Título revista abreviado:Inorg. Chem. Commun.
ISSN:13877003
CODEN:ICCOF
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13877003_v51_n_p110_Martinez

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Citas:

---------- APA ----------
Martínez, M.D., Rustoy, E.M., Raggio, N. & Burton, G. (2015) . Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T. Inorganic Chemistry Communications, 51, 110-113.
http://dx.doi.org/10.1016/j.inoche.2014.11.019
---------- CHICAGO ----------
Martínez, M.D., Rustoy, E.M., Raggio, N., Burton, G. "Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T" . Inorganic Chemistry Communications 51 (2015) : 110-113.
http://dx.doi.org/10.1016/j.inoche.2014.11.019
---------- MLA ----------
Martínez, M.D., Rustoy, E.M., Raggio, N., Burton, G. "Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T" . Inorganic Chemistry Communications, vol. 51, 2015, pp. 110-113.
http://dx.doi.org/10.1016/j.inoche.2014.11.019
---------- VANCOUVER ----------
Martínez, M.D., Rustoy, E.M., Raggio, N., Burton, G. Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T. Inorg. Chem. Commun. 2015;51:110-113.
http://dx.doi.org/10.1016/j.inoche.2014.11.019