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Abstract:

In this article, we describe the synthesis of a small library of short peptoids composed of four glycine residues and acylated with a fatty acid that showed a remarkable in vitro activity against two fungal plant pathogens. Their straightforward synthesis implied two consecutive Ugi reactions and can be efficiently extended to the construction of highly diverse libraries. © 2011 Springer Science+Business Media B.V.

Registro:

Documento: Artículo
Título:Multicomponent synthesis of acylated short peptoids with antifungal activity against plant pathogens
Autor:Galetti, M.D.; Cirigliano, A.M.; Cabrera, G.M.; Ramírez, J.A.
Filiación:Departamento de Química Orgánica, UMYMFOR (CONICET - Facultad de Ciencias Exactas Y Naturales), Universidad de Buenos Aires, C1428EGA, Buenos Aires, Argentina
Palabras clave:Acylated peptoids; Antifungal; Multicomponent reaction; Plant pathogen; glycine; peptoid; acylation; antifungal activity; article; chemical reaction; drug structure; drug synthesis; electrospray mass spectrometry; minimum inhibitory concentration; nonhuman; plant disease; priority journal; ugi reaction; Acylation; Amines; Antifungal Agents; Fusarium; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Peptoids; Plants; Spectrometry, Mass, Electrospray Ionization
Año:2012
Volumen:16
Número:1
Página de inicio:113
Página de fin:119
DOI: http://dx.doi.org/10.1007/s11030-011-9334-1
Título revista:Molecular Diversity
Título revista abreviado:Mol. Diversity
ISSN:13811991
CODEN:MODIF
CAS:glycine, 56-40-6, 6000-43-7, 6000-44-8; Amines; Antifungal Agents; Peptoids
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13811991_v16_n1_p113_Galetti

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Citas:

---------- APA ----------
Galetti, M.D., Cirigliano, A.M., Cabrera, G.M. & Ramírez, J.A. (2012) . Multicomponent synthesis of acylated short peptoids with antifungal activity against plant pathogens. Molecular Diversity, 16(1), 113-119.
http://dx.doi.org/10.1007/s11030-011-9334-1
---------- CHICAGO ----------
Galetti, M.D., Cirigliano, A.M., Cabrera, G.M., Ramírez, J.A. "Multicomponent synthesis of acylated short peptoids with antifungal activity against plant pathogens" . Molecular Diversity 16, no. 1 (2012) : 113-119.
http://dx.doi.org/10.1007/s11030-011-9334-1
---------- MLA ----------
Galetti, M.D., Cirigliano, A.M., Cabrera, G.M., Ramírez, J.A. "Multicomponent synthesis of acylated short peptoids with antifungal activity against plant pathogens" . Molecular Diversity, vol. 16, no. 1, 2012, pp. 113-119.
http://dx.doi.org/10.1007/s11030-011-9334-1
---------- VANCOUVER ----------
Galetti, M.D., Cirigliano, A.M., Cabrera, G.M., Ramírez, J.A. Multicomponent synthesis of acylated short peptoids with antifungal activity against plant pathogens. Mol. Diversity. 2012;16(1):113-119.
http://dx.doi.org/10.1007/s11030-011-9334-1