Artículo

Monsalve, L.N.; Rosselli, S.; Bruno, M.; Baldessari, A. "Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin" (2009) Journal of Molecular Catalysis B: Enzymatic. 57(1-4):40-47
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Abstract:

Several acyl derivatives of cnicin were obtained through lipase-catalysed acylation and alcoholysis reactions. In most reactions lipases showed a regioselective behaviour affording only one product. Longer chain acyl derivatives were prepared at lower temperature than the used in lipase-catalysed reactions, to preclude side products formation. The enzymatic approach let to prepare a family of novel acetyl and fatty acid derivatives of cnicin which are not obtainable following traditional organic synthetic procedures. © 2008 Elsevier B.V. All rights reserved.

Registro:

Documento: Artículo
Título:Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin
Autor:Monsalve, L.N.; Rosselli, S.; Bruno, M.; Baldessari, A.
Filiación:Laboratorio de Biocatálisis, Departamento de Química Orgánica y UMYMFOR, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, C1428EGA Buenos Aires, Argentina
Dipartimento di Chimica Organica, Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy
Palabras clave:Acylation; Alcoholysis; Cnicin; Enzyme catalysis; Sesquiterpenoids; Acyl derivatives; Alcoholysis; Alcoholysis reactions; Cnicin; Enzyme catalysis; Fatty acid derivatives; Germacranolide; Regio-selective; Sesquiterpenoids; Side products; Synthetic procedures; Acylation; Enzymes; Fatty acids; Lipases; Catalysis; acetic acid derivative; cnicin; fatty acid derivative; germacranolide derivative; sesquiterpene lactone; triacylglycerol lipase; unclassified drug; acylation; alcoholysis; article; catalysis; chemical reaction kinetics; chemical structure; controlled study; enantioselectivity; enzyme activity; low temperature; nonhuman; synthesis
Año:2009
Volumen:57
Número:1-4
Página de inicio:40
Página de fin:47
DOI: http://dx.doi.org/10.1016/j.molcatb.2008.06.019
Título revista:Journal of Molecular Catalysis B: Enzymatic
Título revista abreviado:J. Mol. Catal. B Enzym.
ISSN:13811177
CODEN:JMCEF
CAS:cnicin, 24394-09-0; triacylglycerol lipase, 9001-62-1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13811177_v57_n1-4_p40_Monsalve

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Citas:

---------- APA ----------
Monsalve, L.N., Rosselli, S., Bruno, M. & Baldessari, A. (2009) . Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin. Journal of Molecular Catalysis B: Enzymatic, 57(1-4), 40-47.
http://dx.doi.org/10.1016/j.molcatb.2008.06.019
---------- CHICAGO ----------
Monsalve, L.N., Rosselli, S., Bruno, M., Baldessari, A. "Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin" . Journal of Molecular Catalysis B: Enzymatic 57, no. 1-4 (2009) : 40-47.
http://dx.doi.org/10.1016/j.molcatb.2008.06.019
---------- MLA ----------
Monsalve, L.N., Rosselli, S., Bruno, M., Baldessari, A. "Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin" . Journal of Molecular Catalysis B: Enzymatic, vol. 57, no. 1-4, 2009, pp. 40-47.
http://dx.doi.org/10.1016/j.molcatb.2008.06.019
---------- VANCOUVER ----------
Monsalve, L.N., Rosselli, S., Bruno, M., Baldessari, A. Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin. J. Mol. Catal. B Enzym. 2009;57(1-4):40-47.
http://dx.doi.org/10.1016/j.molcatb.2008.06.019