Artículo
Médici, R.; Lewkowicz, E.S.; Iribarren, A.M. "Microbial synthesis of 2,6-diaminopurine nucleosides" (2006) Journal of Molecular Catalysis B: Enzymatic. 39(1-4):40-44
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Abstract:
2,6-Diaminopurine nucleosides are used as pharmaceutical drugs or prodrugs against cancer and viral diseases. The synthesis of 2,6-diaminopurine riboside, -2′-deoxyriboside, -2′,3′-dideoxyriboside and -arabinofuranoside was efficiently carried out by transglycosylation using bacterial whole cells as biocatalysts. The preparation of 2,6-diaminopurine-2′,3′-dideoxyriboside catalysed by whole cells is here reported for the first time. © 2006 Elsevier B.V. All rights reserved.
Registro:
| Documento: | Artículo |
| Título: | Microbial synthesis of 2,6-diaminopurine nucleosides |
| Autor: | Médici, R.; Lewkowicz, E.S.; Iribarren, A.M. |
| Filiación: | Universidad Nacional de Quilmes. R.S. Peña 180, 1876 Bernal Buenos Aires, Argentina INGEBI, CONICET, Vuelta de Obligado 2490, 1428 Buenos Aires, Argentina |
| Palabras clave: | 2,6-Diaminopurine nucleoside; Microbial transglycosylation; Nucleoside analogues; Whole cells; Bacteria; Biocatalysts; Derivatives; Diseases; Drug products; Synthesis (chemical); Microbial transglycosylation; Nucleoside analogues; Nucleosides; Whole cells; Nitrogen compounds; 2 aminoadenosine; 2' deoxyriboside; 2',3' dideoxyriboside; arabinofuranoside; nucleoside derivative; unclassified drug; Achromobacter; Aeromonas; Arthrobacter; article; Bacillus; bacterial cell; biocatalyst; Brevibacterium; Cellulomonas; Citrobacter; Corynebacterium; drug synthesis; Enterobacter; Erwinia; Escherichia coli; glycosylation; Klebsiella; Micrococcus; nonhuman; Proteus; Pseudomonas; Rhizobium; Serratia; Staphylococcus; whole cell; Xanthomonas; Achromobacter; Aeromonas; Arthrobacter; Bacillus (bacterium); Bacteria (microorganisms); Brevibacterium; Cellulomonas; Citrobacter; Corynebacterium; Enterobacter; Erwinia; Escherichia coli; Klebsiella; Micrococcus; Proteus (enterobacteria); Pseudomonas; Rhizobium; Serratia; Staphylococcus; Xanthomonas |
| Año: | 2006 |
| Volumen: | 39 |
| Número: | 1-4 |
| Página de inicio: | 40 |
| Página de fin: | 44 |
| DOI: | http://dx.doi.org/10.1016/j.molcatb.2006.01.024 |
| Título revista: | Journal of Molecular Catalysis B: Enzymatic |
| Título revista abreviado: | J. Mol. Catal. B Enzym. |
| ISSN: | 13811177 |
| CODEN: | JMCEF |
| CAS: | 2 aminoadenosine, 2096-10-8 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13811177_v39_n1-4_p40_Medici |
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Citas:
---------- APA ----------
Médici, R., Lewkowicz, E.S. & Iribarren, A.M. (2006) . Microbial synthesis of 2,6-diaminopurine nucleosides. Journal of Molecular Catalysis B: Enzymatic, 39(1-4), 40-44.http://dx.doi.org/10.1016/j.molcatb.2006.01.024
---------- CHICAGO ----------
Médici, R., Lewkowicz, E.S., Iribarren, A.M. "Microbial synthesis of 2,6-diaminopurine nucleosides" . Journal of Molecular Catalysis B: Enzymatic 39, no. 1-4 (2006) : 40-44.http://dx.doi.org/10.1016/j.molcatb.2006.01.024
---------- MLA ----------
Médici, R., Lewkowicz, E.S., Iribarren, A.M. "Microbial synthesis of 2,6-diaminopurine nucleosides" . Journal of Molecular Catalysis B: Enzymatic, vol. 39, no. 1-4, 2006, pp. 40-44.http://dx.doi.org/10.1016/j.molcatb.2006.01.024
---------- VANCOUVER ----------
Médici, R., Lewkowicz, E.S., Iribarren, A.M. Microbial synthesis of 2,6-diaminopurine nucleosides. J. Mol. Catal. B Enzym. 2006;39(1-4):40-44.http://dx.doi.org/10.1016/j.molcatb.2006.01.024
