Artículo
Alvarez-Paggi, D.; Abriata, L.A.; Murgida, D.H.; Vila, A.J. "Native CuA redox sites are largely resilient to pH variations within a physiological range" (2013) Chemical Communications. 49(47):5381-5383
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Abstract:
Previous studies on engineered CuA centres have shown that one of the histidine ligands is protonated and dissociated from the metal site at physiological pH values, thus suggesting a role in regulating proton-coupled electron transfer of cytochrome c oxidases in vivo. Here we report that for native CuA such protonation does not take place at physiologically relevant pH values and, furthermore, no significant changes in the spectroscopic and redox properties of the metal site occur at low pH. © 2013 The Royal Society of Chemistry.
Registro:
| Documento: | Artículo |
| Título: | Native CuA redox sites are largely resilient to pH variations within a physiological range |
| Autor: | Alvarez-Paggi, D.; Abriata, L.A.; Murgida, D.H.; Vila, A.J. |
| Filiación: | Departamento de Quimica Inorganica, Analitica y Quimica Fisica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428EHA Buenos Aires, Argentina Instituto de Biología Molecular y Celular de Rosario (IBR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, 2000 Rosario, Argentina |
| Palabras clave: | copper; metal; article; chemical structure; electron; excitation; oxidation reduction reaction; pH; physiology; proton transport; spectroscopy; Copper; Electrochemistry; Electron Transport Complex IV; Hydrogen-Ion Concentration; Oxidation-Reduction; Spectrum Analysis |
| Año: | 2013 |
| Volumen: | 49 |
| Número: | 47 |
| Página de inicio: | 5381 |
| Página de fin: | 5383 |
| DOI: | http://dx.doi.org/10.1039/c3cc40457a |
| Título revista: | Chemical Communications |
| Título revista abreviado: | Chem. Commun. |
| ISSN: | 13597345 |
| CODEN: | CHCOF |
| CAS: | copper, 15158-11-9, 7440-50-8; Copper, 789U1901C5; Electron Transport Complex IV, 1.9.3.1 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13597345_v49_n47_p5381_AlvarezPaggi |
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Citas:
---------- APA ----------
Alvarez-Paggi, D., Abriata, L.A., Murgida, D.H. & Vila, A.J. (2013) . Native CuA redox sites are largely resilient to pH variations within a physiological range. Chemical Communications, 49(47), 5381-5383.http://dx.doi.org/10.1039/c3cc40457a
---------- CHICAGO ----------
Alvarez-Paggi, D., Abriata, L.A., Murgida, D.H., Vila, A.J. "Native CuA redox sites are largely resilient to pH variations within a physiological range" . Chemical Communications 49, no. 47 (2013) : 5381-5383.http://dx.doi.org/10.1039/c3cc40457a
---------- MLA ----------
Alvarez-Paggi, D., Abriata, L.A., Murgida, D.H., Vila, A.J. "Native CuA redox sites are largely resilient to pH variations within a physiological range" . Chemical Communications, vol. 49, no. 47, 2013, pp. 5381-5383.http://dx.doi.org/10.1039/c3cc40457a
---------- VANCOUVER ----------
Alvarez-Paggi, D., Abriata, L.A., Murgida, D.H., Vila, A.J. Native CuA redox sites are largely resilient to pH variations within a physiological range. Chem. Commun. 2013;49(47):5381-5383.http://dx.doi.org/10.1039/c3cc40457a
