Abstract:
The electrochemistry of ubiquinone-10, UQ, incorporated over a phospholipid layer adsorbed on a mercury drop electrode has been investigated over a wide pH range. It is shown that the position of the quinone headgroup in relation to the lipid determines the reversibility of the redox chemistry. For pH < 7, the reaction follows a disproportionation route involving the ubiquinone radical. There is evidence for the presence of a parallel reaction sequence. The bifurcation point appears to occur for the UQ molecule, which disproportionates after protonation and reduction, in parallel with direct electron transfer to yield the UQ:- radical anion. The incorporation of UQ in a lipid monolayer makes its reduction very irreversible for pH > 7.
Registro:
Documento: |
Artículo
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Título: | The electrochemistry of ubiquinone-10 in a phospholipid model membrane |
Autor: | Gordillo, G.J.; Schiffrin, D.J. |
Filiación: | INQUIMAE, Departamento de Química, Universidad de Buenos Aires, Buenos Aires, 1428, Argentina Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD, United Kingdom
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Palabras clave: | phospholipid; ubiquinone; algorithm; article; artificial membrane; chemistry; electrochemistry; oxidation reduction reaction; pH; Algorithms; Electrochemistry; Hydrogen-Ion Concentration; Membranes, Artificial; Oxidation-Reduction; Phospholipids; Ubiquinone |
Año: | 2000
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Volumen: | 116
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Página de inicio: | 89
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Página de fin: | 107
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DOI: |
http://dx.doi.org/10.1039/b004379f |
Título revista: | Faraday Discussions
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Título revista abreviado: | Faraday Discuss.
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ISSN: | 13596640
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CAS: | Membranes, Artificial; Phospholipids; Ubiquinone, 1339-63-5
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13596640_v116_n_p89_Gordillo |
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Citas:
---------- APA ----------
Gordillo, G.J. & Schiffrin, D.J.
(2000)
. The electrochemistry of ubiquinone-10 in a phospholipid model membrane. Faraday Discussions, 116, 89-107.
http://dx.doi.org/10.1039/b004379f---------- CHICAGO ----------
Gordillo, G.J., Schiffrin, D.J.
"The electrochemistry of ubiquinone-10 in a phospholipid model membrane"
. Faraday Discussions 116
(2000) : 89-107.
http://dx.doi.org/10.1039/b004379f---------- MLA ----------
Gordillo, G.J., Schiffrin, D.J.
"The electrochemistry of ubiquinone-10 in a phospholipid model membrane"
. Faraday Discussions, vol. 116, 2000, pp. 89-107.
http://dx.doi.org/10.1039/b004379f---------- VANCOUVER ----------
Gordillo, G.J., Schiffrin, D.J. The electrochemistry of ubiquinone-10 in a phospholipid model membrane. Faraday Discuss. 2000;116:89-107.
http://dx.doi.org/10.1039/b004379f