Artículo

Casellini, C.; Citera, G.; Rosemffet, M.; Ruggeri, S.; Saviotti, A.; Maldonado Cocco, J.A. "Audiovestibular disorders in patients with ankylosing spondylitis" (2005) Journal of Clinical Rheumatology. 11(2):81-85
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Abstract:

Objective: Audiovestibular disorders have been described in several autoimmune diseases but have not been studied in patients with ankylosing spondylitis (AS). The aim of this study was to evaluate the audiovestibular function in patients with AS. Methods: We prospectively evaluated 22 consecutive patients with AS. Clinical, radiologic, and immunogenetic features were analyzed. All patients underwent a complete ear, nose, and throat physical examination and audiologic evaluation that included pure-tone audiometry thresholds at octave frequencies of 250 to 8000 Hz, impedance audiometry (tympanogram, static compliance, acoustic reflexes, and reflex decay), and speech audiometry. Thirty-one healthy volunteers and 26 patients with rheumatoid arthritis (RA) were included as controls. Results: Patients with AS had a median age of 45.5 years (interquartile range [IQR] 38-54) and a median disease duration of 20 years (IQR 12.5-26.2). Otosclerosis was observed in 2 patients with AS (9.1%), 3 patients with RA (11.5%), but not in any healthy controls (P = not significant). Sensorineural hearing loss (SNHL) was observed in 13 patients with AS (59%), 17 patients with RA (65.4%), and 13 healthy controls (41.9%) without statistically significant differences. Because age can influence audiometric results, patients and controls were divided into 4 age groups. A higher frequency of SNHL was observed in patients with AS from 45 to 59 years compared with healthy controls and patients with RA (87% versus 20%, P = 0.03, versus 70%, P = not significant, respectively). Conclusion: Middle-aged patients with AS had a significantly higher frequency of SNHL compared with controls. SNHL should be considered as a possible complication of AS as well as of RA and other autoimmune diseases. Possible toxic effect of nonsteroidal antiinflammatory drugs should also be considered in such patients. Copyright © 2005 by Lippincott Williams & Wilkins.

Registro:

Documento: Artículo
Título:Audiovestibular disorders in patients with ankylosing spondylitis
Autor:Casellini, C.; Citera, G.; Rosemffet, M.; Ruggeri, S.; Saviotti, A.; Maldonado Cocco, J.A.
Filiación:Section of Rheumatology, Inst. de Rehabilitacion Psicofisica, Buenos Aires, Argentina
Section of Otolaryngology, Hospital Italiano, Buenos Aires, Argentina
Inst. de Rehabilitacion Psicofisica, Section of Rheumatology, Escheverria 995, 1428 Buenos Aires, Argentina
Palabras clave:Ankylosing spondylitis; Audiovestibular disorders; Otosclerosis; Sensorineural hearing loss; methotrexate; salazosulfapyridine; salicylic acid derivative; steroid; adult; ankylosing spondylitis; article; audiometry; auditory nervous system; autoimmune disease; clinical article; comorbidity; controlled study; disease activity; female; hearing disorder; human; hypoacusis; male; otosclerosis; priority journal; tympanometry; vestibular disorder; vestibular function; Adult; Age Factors; Aged; Audiometry; Case-Control Studies; Cochlear Nerve; Female; Hearing Loss, Sensorineural; Humans; Male; Middle Aged; Otosclerosis; Prospective Studies; Spondylitis, Ankylosing; Vestibular Nerve
Año:2005
Volumen:11
Número:2
Página de inicio:81
Página de fin:85
DOI: http://dx.doi.org/10.1097/01.rhu.0000158542.43099.35
Título revista:Journal of Clinical Rheumatology
Título revista abreviado:J. Clin. Rheumatol.
ISSN:10761608
CODEN:JCRHF
CAS:methotrexate, 15475-56-6, 59-05-2, 7413-34-5; salazosulfapyridine, 599-79-1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10761608_v11_n2_p81_Casellini

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Citas:

---------- APA ----------
Casellini, C., Citera, G., Rosemffet, M., Ruggeri, S., Saviotti, A. & Maldonado Cocco, J.A. (2005) . Audiovestibular disorders in patients with ankylosing spondylitis. Journal of Clinical Rheumatology, 11(2), 81-85.
http://dx.doi.org/10.1097/01.rhu.0000158542.43099.35
---------- CHICAGO ----------
Casellini, C., Citera, G., Rosemffet, M., Ruggeri, S., Saviotti, A., Maldonado Cocco, J.A. "Audiovestibular disorders in patients with ankylosing spondylitis" . Journal of Clinical Rheumatology 11, no. 2 (2005) : 81-85.
http://dx.doi.org/10.1097/01.rhu.0000158542.43099.35
---------- MLA ----------
Casellini, C., Citera, G., Rosemffet, M., Ruggeri, S., Saviotti, A., Maldonado Cocco, J.A. "Audiovestibular disorders in patients with ankylosing spondylitis" . Journal of Clinical Rheumatology, vol. 11, no. 2, 2005, pp. 81-85.
http://dx.doi.org/10.1097/01.rhu.0000158542.43099.35
---------- VANCOUVER ----------
Casellini, C., Citera, G., Rosemffet, M., Ruggeri, S., Saviotti, A., Maldonado Cocco, J.A. Audiovestibular disorders in patients with ankylosing spondylitis. J. Clin. Rheumatol. 2005;11(2):81-85.
http://dx.doi.org/10.1097/01.rhu.0000158542.43099.35