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Abstract:

Memory reconsolidation is defined as a process in which the retrieval of a previously consolidated memory returns to a labile state which is then subject to stabilization. The reminder is the event that begins with the presentation of the learned cue and triggers the labilization-reconsolidation process. Since the early formulation of the hypothesis, several controversial items have arisen concerning the conditions that define reconsolidation. It is herein proposed that two diagnostic features characterize reconsolidation, namely: the labilization of the reactivated memory and the specificity of the reminder structure. To study this proposal, subjects received two different training sessions on verbal material on Day 1 and Day 2, respectively. Finally, they were tested for the first and second acquired memories on Day 3. It is demonstrated that the human declarative memory fulfills the two requirements that define the process. First, the reactivated memory is impaired by a new learning only when it is given closely after the reminder, revealing that the memory is labilized. Second, the omission of at least one of the reminder's components prevents labilization. Therefore, results show that the new learning fails to produce an amnesic effect on the target memory either when the reminder omits the learned cue or includes the beginning of the reinforcement. © 2008 Elsevier Inc. All rights reserved.

Registro:

Documento: Artículo
Título:Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure
Autor:Forcato, C.; Argibay, P.F.; Pedreira, M.E.; Maldonado, H.
Filiación:Laboratorio de Neurobiología de la Memoria, Departamento de Fisiología y Biología Molecular y Celular, IFIBYNE-CONICET, Pabellón 2, Buenos Aires 1428, Argentina
Unidad de Ciencias Cognitivas, Instituto de Ciencias Básicas y Medicina Experimental, Hospital Italiano de Buenos Aires, C1181ACH Buenos Aires, Argentina
Palabras clave:Declarative memory; Mismatching; Reconsolidation; Reminder structure; Retrieval-induced-forgetting (RIF); adult; article; controlled study; declarative memory; female; human; learning; male; memory; memory consolidation; memory disorder; normal human; reinforcement; task performance; verbal behavior; Adult; Analysis of Variance; Association Learning; Cues; Female; Humans; Male; Memory; Mental Recall; Models, Psychological; Phonetics; Young Adult
Año:2009
Volumen:91
Número:1
Página de inicio:50
Página de fin:57
DOI: http://dx.doi.org/10.1016/j.nlm.2008.09.011
Título revista:Neurobiology of Learning and Memory
Título revista abreviado:Neurobiol. Learn. Mem.
ISSN:10747427
CODEN:NLMEF
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10747427_v91_n1_p50_Forcato

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Citas:

---------- APA ----------
Forcato, C., Argibay, P.F., Pedreira, M.E. & Maldonado, H. (2009) . Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure. Neurobiology of Learning and Memory, 91(1), 50-57.
http://dx.doi.org/10.1016/j.nlm.2008.09.011
---------- CHICAGO ----------
Forcato, C., Argibay, P.F., Pedreira, M.E., Maldonado, H. "Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure" . Neurobiology of Learning and Memory 91, no. 1 (2009) : 50-57.
http://dx.doi.org/10.1016/j.nlm.2008.09.011
---------- MLA ----------
Forcato, C., Argibay, P.F., Pedreira, M.E., Maldonado, H. "Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure" . Neurobiology of Learning and Memory, vol. 91, no. 1, 2009, pp. 50-57.
http://dx.doi.org/10.1016/j.nlm.2008.09.011
---------- VANCOUVER ----------
Forcato, C., Argibay, P.F., Pedreira, M.E., Maldonado, H. Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure. Neurobiol. Learn. Mem. 2009;91(1):50-57.
http://dx.doi.org/10.1016/j.nlm.2008.09.011