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Abstract:

Angiotensin II (ANGII) has an evolutionary preserved role in determining adaptative responses to water-shortages. In addition, it has been shown to modulate diverse phases of memory. Still, it is not clear whether ANGII improves or spoils memory. We demonstrated that endogenous angiotensins enhance consolidation of a long-term associative memory in the crab Chasmagnathus and that water shortage improves memory consolidation through brain ANGII actions. Here, we show that weakly trained crabs, when water-deprived, exhibit enhanced retrieval. Subsequently, memory retention is indistinguishable from that of strongly trained crabs. ANGII, but not angiotensin IV, is a necessary and sufficient condition for such enhancing effect. We conclude that ANGII released due to water shortage leads to enhanced memory retrieval. Thus, it seems that ANGII has an evolutionary preserved role as a multifunction coordinator that enables an adaptative response to water-shortage. The facilitation of memory consolidation and retrieval would be among those coordinated functions. © 2004 Elsevier Inc. All rights reserved.

Registro:

Documento: Artículo
Título:Retrieval improvement is induced by water shortage through angiotensin II
Autor:Frenkel, L.; Maldonado, H.; Delorenzi, A.
Filiación:Lab. de Neurbio. de la Memoria, Depto. Fisiol. Y Biol. Molec. Y Cel., IFIBYNE-CONICET, Argentina
Palabras clave:Angiotensin; Crustacea; Invertebrate; Memory; Neuropeptide; Osmoregulation; Retrieval; angiotensin; angiotensin II [3-8]; angiotensin receptor antagonist; dival; saralasin; unclassified drug; water; wsu 1291; adaptation; animal experiment; article; controlled study; crab; memory; memory consolidation; nonhuman; protein function; protein secretion; recall; training; water deprivation
Año:2005
Volumen:83
Número:2
Página de inicio:173
Página de fin:177
DOI: http://dx.doi.org/10.1016/j.nlm.2004.11.001
Título revista:Neurobiology of Learning and Memory
Título revista abreviado:Neurobiol. Learn. Mem.
ISSN:10747427
CODEN:NLMEF
CAS:angiotensin, 1407-47-2; saralasin, 34273-10-4; water, 7732-18-5
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10747427_v83_n2_p173_Frenkel

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Citas:

---------- APA ----------
Frenkel, L., Maldonado, H. & Delorenzi, A. (2005) . Retrieval improvement is induced by water shortage through angiotensin II. Neurobiology of Learning and Memory, 83(2), 173-177.
http://dx.doi.org/10.1016/j.nlm.2004.11.001
---------- CHICAGO ----------
Frenkel, L., Maldonado, H., Delorenzi, A. "Retrieval improvement is induced by water shortage through angiotensin II" . Neurobiology of Learning and Memory 83, no. 2 (2005) : 173-177.
http://dx.doi.org/10.1016/j.nlm.2004.11.001
---------- MLA ----------
Frenkel, L., Maldonado, H., Delorenzi, A. "Retrieval improvement is induced by water shortage through angiotensin II" . Neurobiology of Learning and Memory, vol. 83, no. 2, 2005, pp. 173-177.
http://dx.doi.org/10.1016/j.nlm.2004.11.001
---------- VANCOUVER ----------
Frenkel, L., Maldonado, H., Delorenzi, A. Retrieval improvement is induced by water shortage through angiotensin II. Neurobiol. Learn. Mem. 2005;83(2):173-177.
http://dx.doi.org/10.1016/j.nlm.2004.11.001