Abstract:
In this issue of Chemistry & Biology, Grossman et al. report a study on aldosterone-dependent nuclear translocation of the mineralocorticoid receptor (MR). They analyze the dependency of MR retrotransport, DNA-binding, and transcriptional activity on Hsp90 and demonstrate that MR dimerization is a nuclear event. © 2012 Elsevier Ltd All rights reserved.
Registro:
Documento: |
Artículo
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Título: | Steroid receptor coupling becomes nuclear |
Autor: | Galigniana, M.D. |
Filiación: | Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires C1428ADN, Argentina
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Palabras clave: | aldosterone; geldanamycin; heat shock protein 90; mineralocorticoid receptor; cell nucleus; dimerization; DNA binding; drug mechanism; gene expression regulation; genetic transcription; human; protein localization; review |
Año: | 2012
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Volumen: | 19
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Número: | 6
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Página de inicio: | 662
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Página de fin: | 663
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DOI: |
http://dx.doi.org/10.1016/j.chembiol.2012.06.001 |
Título revista: | Chemistry and Biology
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Título revista abreviado: | Chem. Biol.
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ISSN: | 10745521
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CODEN: | CBOLE
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CAS: | aldosterone, 52-39-1, 6251-69-0; geldanamycin, 30562-34-6
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10745521_v19_n6_p662_Galigniana |
Referencias:
- Dahmer, M.K., Housley, P.R., Pratt, W.B., (1984) Annu. Rev. Physiol., 46, pp. 67-81
- Echeverría, P.C., Mazaira, G., Erlejman, A., Gomez-Sanchez, C., Piwien Pilipuk, G., Galigniana, M.D., (2009) Mol. Cell. Biol., 29, pp. 4788-4797
- Galigniana, M.D., Echeverría, P.C., Erlejman, A.G., Piwien-Pilipuk, G., (2010) Nucleus, 1, pp. 299-308
- Galigniana, M.D., Erlejman, A.G., Monte, M., Gomez-Sanchez, C., Piwien-Pilipuk, G., (2010) Mol. Cell. Biol., 30, pp. 1285-1298
- Gallo, L.I., Ghini, A.A., Piwien Pilipuk, G., Galigniana, M.D., (2007) Biochemistry, 46, pp. 14044-14057
- Grossman, C., Ruhs, S., Langenbruch, L., Mildenberger, S., Strätz, N., Schumann, K., Gekle, M., (2012) Chem. Biol., 19, pp. 742-751. , this issue
- Heitzer, M.D., Wolf, I.M., Sanchez, E.R., Witchel, S.F., Defranco, D.B., (2007) Rev. Endocr. Metab. Disord., 8, pp. 321-330
- Pratt, W.B., Galigniana, M.D., Harrell, J.M., Defranco, D.B., (2004) Cell. Signal., 16, pp. 857-872
- Presman, D.M., Alvarez, L.D., Levi, V., Eduardo, S., Digman, M.A., Martí, M.A., Veleiro, A.S., Pecci, A., (2010) PLoS ONE, 5, p. 13279
- Segard-Maurel, I., Rajkowski, K., Jibard, N., Schweizer-Groyer, G., Baulieu, E.E., Cadepond, F., (1996) Biochemistry, 35, pp. 1634-1642
- Tsai, M.J., O'Malley, B.W., (1994) Annu. Rev. Biochem., 63, pp. 451-486
Citas:
---------- APA ----------
(2012)
. Steroid receptor coupling becomes nuclear. Chemistry and Biology, 19(6), 662-663.
http://dx.doi.org/10.1016/j.chembiol.2012.06.001---------- CHICAGO ----------
Galigniana, M.D.
"Steroid receptor coupling becomes nuclear"
. Chemistry and Biology 19, no. 6
(2012) : 662-663.
http://dx.doi.org/10.1016/j.chembiol.2012.06.001---------- MLA ----------
Galigniana, M.D.
"Steroid receptor coupling becomes nuclear"
. Chemistry and Biology, vol. 19, no. 6, 2012, pp. 662-663.
http://dx.doi.org/10.1016/j.chembiol.2012.06.001---------- VANCOUVER ----------
Galigniana, M.D. Steroid receptor coupling becomes nuclear. Chem. Biol. 2012;19(6):662-663.
http://dx.doi.org/10.1016/j.chembiol.2012.06.001