Pinto, V.E.F.; Patriarca, A."Alternaria species and their associated mycotoxins" (2017) Methods in Molecular Biology. 1542:13-32
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The genus Alternaria includes more than 250 species. The traditional methods for identification of Alternaria species are based on morphological characteristics of the reproductive structures and sporulation patterns under controlled culture conditions. Cladistics analyses of “housekeeping genes” commonly used for other genera, failed to discriminate among the small-spored Alternaria species. The development of molecular methods achieving a better agreement with morphological differences is still needed. The production of secondary metabolites has also been used as a means of classification and identification. Alternaria spp. can produce a wide variety of toxic metabolites. These metabolites belong principally to three different structural groups: (1) the dibenzopyrone derivatives, alternariol (AOH), alternariol monomethyl ether (AME), and altenuene (ALT); (2) the perylene derivative altertoxins (ATX-I, ATX-II, and ATX II); and (3) the tetramic acid derivative, tenuazonic acid (TeA). TeA, AOH, AME, ALT, and ATX-I are the main. Certain species in the genus Alternaria produce host-specific toxins (HSTs) that contribute to their pathogenicity and virulence. Alternaria species are plant pathogens that cause spoilage of agricultural commodities with consequent mycotoxin accumulation and economic losses. Vegetable foods infected by Alternaria rot could introduce high amounts of these toxins to the human diet. More investigations on the toxic potential of these toxins and their hazard for human consumption are needed to make a reliable risk assessment of dietary exposure. © Springer Science+Business Media LLC 2017.


Documento: Artículo
Título:Alternaria species and their associated mycotoxins
Autor:Pinto, V.E.F.; Patriarca, A.
Filiación:Laboratorio de Microbiología de Alimentos, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Pab. II- 3° Piso- Ciudad Universitaria, Universidad de Buenos Aires, Buenos Aires, 1428, Argentina
Palabras clave:Alternaria species; Fruits; Grains; Mycotoxins; Taxonomy; Vegetables; alternariol; alternariol monomethyl ether; altertoxin; mycotoxin; perylene; tentoxin; tenuazonic acid; tetramic acid derivative; unclassified drug; mycotoxin; Alternaria; apple; cereal; chemotaxonomy; citrus fruit; food; fungal gene; fungal virulence; fungus culture; fungus identification; host; housekeeping gene; metabolite; molecular phylogeny; morphological trait; nonhuman; plant disease; sporogenesis; tomato; Alternaria; animal; animal food; classification; food contamination; food safety; genetics; host pathogen interaction; human; metabolism; metabolome; metabolomics; microbiology; plant; procedures; secondary metabolism; Alternaria; Animal Feed; Animals; Food Contamination; Food Safety; Host-Pathogen Interactions; Humans; Metabolome; Metabolomics; Mycotoxins; Plants; Secondary Metabolism
Página de inicio:13
Página de fin:32
Título revista:Methods in Molecular Biology
Título revista abreviado:Methods Mol. Biol.
CAS:alternariol, 641-38-3; perylene, 198-55-0; tenuazonic acid, 610-88-8, 75652-74-3; Mycotoxins


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---------- APA ----------
Pinto, V.E.F. & Patriarca, A. (2017) . Alternaria species and their associated mycotoxins. Methods in Molecular Biology, 1542, 13-32.
---------- CHICAGO ----------
Pinto, V.E.F., Patriarca, A. "Alternaria species and their associated mycotoxins" . Methods in Molecular Biology 1542 (2017) : 13-32.
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Pinto, V.E.F., Patriarca, A. "Alternaria species and their associated mycotoxins" . Methods in Molecular Biology, vol. 1542, 2017, pp. 13-32.
---------- VANCOUVER ----------
Pinto, V.E.F., Patriarca, A. Alternaria species and their associated mycotoxins. Methods Mol. Biol. 2017;1542:13-32.