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Abstract:

Intra-aortic balloon pumping (IABP) could modify the arterial biomechanics; however, its effects on arterial wall properties have not been fully explored. This dynamical study was designed to characterize the pressure-dependent and smooth muscle-dependent effects of IABP on aortic wall energetics in an in vivo animal model. Intra-aortic balloon pumping (1:2) was performed in six anesthetized sheep in which aortic pressure and diameter signals were measured in basal, augmented (during balloon inflation), and assisted (postaugmented) beats. Energy dissipation values in augmented and assisted beats were significantly higher than those observed in basal state (p < 0.05). Assisted beats showed a significant increase of wall damping with respect to basal and augmented beats (p < 0.05). Intra-aortic balloon pumping resulted in a significant increase of pulse wave velocity (p < 0.05) in augmented beats with respect to basal state (6.3 ± 0.8 vs. 5.2 ± 0.5 m·s); whereas values observed in assisted beats were significantly (p < 0.05) lower than those observed in augmented beats (4.9 ± 0.5 vs. 6.3 ± 0.8 m·s). Our findings show that IABP determined the pressure and smooth muscle-dependent changes in arterial wall energetics and damping properties in this animal model. ©2008Amercian Society of Artificial Internal Organs.

Registro:

Documento: Artículo
Título:Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments
Autor:Fischer, E.I.C.; Bia, D.; Camus, J.M.; Zócalo, Y.; De Forteza, E.; Armentano, R.L.
Filiación:Facultdad de Ingenieria Y Ciencias Exactas Y Naturales, Favaloro University, Buenos Aires, Argentina
CONICET, Buenos Aires, Argentina
Physiology Department, School of Medicine, Republic University, Montevideo, Uruguay
Physiology Department, School of Medicine, Republic University, General Flores 2125, (11800), Montevideo, Uruguay
Palabras clave:Cardiology; Energy dissipation; Physiological models; Pressure effects; Aortic pressure; Aortic wall energetics; Intra-aortic balloon pumping (IABP); Intra-aortic counterpulsation; Biomechanics; animal cell; animal experiment; animal model; animal tissue; aorta balloon; aorta pressure; aorta wall; article; biomechanics; controlled study; counterpulsation; in vivo study; mathematical computing; nonhuman; pulse wave; sheep; smooth muscle; Animals; Aorta; Cardiac Output; Cardiology; Coronary Circulation; Coronary Vessels; Counterpulsation; Disease Models, Animal; Heart Failure; Heart Rate; Intra-Aortic Balloon Pumping; Models, Biological; Pressure; Sheep; Time Factors
Año:2008
Volumen:54
Número:1
Página de inicio:44
Página de fin:49
DOI: http://dx.doi.org/10.1097/MAT.0b013e3181611c18
Título revista:ASAIO Journal
Título revista abreviado:ASAIO J.
ISSN:10582916
CODEN:AJOUE
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10582916_v54_n1_p44_Fischer

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Citas:

---------- APA ----------
Fischer, E.I.C., Bia, D., Camus, J.M., Zócalo, Y., De Forteza, E. & Armentano, R.L. (2008) . Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments. ASAIO Journal, 54(1), 44-49.
http://dx.doi.org/10.1097/MAT.0b013e3181611c18
---------- CHICAGO ----------
Fischer, E.I.C., Bia, D., Camus, J.M., Zócalo, Y., De Forteza, E., Armentano, R.L. "Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments" . ASAIO Journal 54, no. 1 (2008) : 44-49.
http://dx.doi.org/10.1097/MAT.0b013e3181611c18
---------- MLA ----------
Fischer, E.I.C., Bia, D., Camus, J.M., Zócalo, Y., De Forteza, E., Armentano, R.L. "Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments" . ASAIO Journal, vol. 54, no. 1, 2008, pp. 44-49.
http://dx.doi.org/10.1097/MAT.0b013e3181611c18
---------- VANCOUVER ----------
Fischer, E.I.C., Bia, D., Camus, J.M., Zócalo, Y., De Forteza, E., Armentano, R.L. Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments. ASAIO J. 2008;54(1):44-49.
http://dx.doi.org/10.1097/MAT.0b013e3181611c18