Artículo

Schinella, G.; Fantinelli, J.C.; Tournier, H.; Prieto, J.M.; Spegazzini, E.; Debenedetti, S.; Mosca, S.M. "Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate)" (2009) Food Research International. 42(10):1403-1409
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Abstract:

Our objective was to compare the antioxidant properties and cardiovascular effects in ischemia-reperfusion of leaves aqueous extracts of Ilex brasiliensis (B) and Ilex paraguariensis (P). In vitro systems were used to assess the antioxidant properties of the extracts. Isolated rat hearts were treated with both extracts before ischemia and myocardial function was assessed. Thiobarbituric acid reactive substances (TBARS) concentration and reduced glutathione (GSH) were also measured. B extract showed higher total phenols and ascorbic acid contents and a higher scavenging activity of peroxynitrite and ferric reducing antioxidant power (FRAP) than P extract. Postischemic systolic and diastolic functions were improved after B and P treatment. Both extracts decreased TBARS and preserved GSH content. The present study demonstrates that an aqueous extract of I. brasiliensis, similar to I. paraguariensis, protects the myocardium against ischemia-reperfusion injury and attenuates oxidative damage. These effects may be attributed to the potent antioxidant properties of the extract. © 2009 Elsevier Ltd. All rights reserved.

Registro:

Documento: Artículo
Título:Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate)
Autor:Schinella, G.; Fantinelli, J.C.; Tournier, H.; Prieto, J.M.; Spegazzini, E.; Debenedetti, S.; Mosca, S.M.
Filiación:Cátedra de Farmacología Básica, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Buenos Aires, Argentina
Centro de Investigaciones Cardiovasculares, Universidad Nacional de La Plata-CONICET, La Plata, Buenos Aires, Argentina
Department of Pharmacognosy and Phytochemistry, School of Pharmacy University of London, United Kingdom
LABRAM, Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Buenos Aires, Argentina
Palabras clave:Antioxidant capacity; GSH; Ilex brasiliensis; Ilex paraguariensis; Ischemia; Reperfusion; TBARS; Antioxidant capacity; GSH; Ilex brasiliensis; Ilex paraguariensis; Ischemia; Reperfusion; TBARS; Ketones; Organic acids; Phenols; Solvent extraction; Croton ovalifolius; Ilex; Ilex brasiliensis; Ilex paraguariensis; Rattus
Año:2009
Volumen:42
Número:10
Página de inicio:1403
Página de fin:1409
DOI: http://dx.doi.org/10.1016/j.foodres.2009.07.004
Título revista:Food Research International
Título revista abreviado:Food Res. Int.
ISSN:09639969
CODEN:FORIE
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09639969_v42_n10_p1403_Schinella

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Citas:

---------- APA ----------
Schinella, G., Fantinelli, J.C., Tournier, H., Prieto, J.M., Spegazzini, E., Debenedetti, S. & Mosca, S.M. (2009) . Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate). Food Research International, 42(10), 1403-1409.
http://dx.doi.org/10.1016/j.foodres.2009.07.004
---------- CHICAGO ----------
Schinella, G., Fantinelli, J.C., Tournier, H., Prieto, J.M., Spegazzini, E., Debenedetti, S., et al. "Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate)" . Food Research International 42, no. 10 (2009) : 1403-1409.
http://dx.doi.org/10.1016/j.foodres.2009.07.004
---------- MLA ----------
Schinella, G., Fantinelli, J.C., Tournier, H., Prieto, J.M., Spegazzini, E., Debenedetti, S., et al. "Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate)" . Food Research International, vol. 42, no. 10, 2009, pp. 1403-1409.
http://dx.doi.org/10.1016/j.foodres.2009.07.004
---------- VANCOUVER ----------
Schinella, G., Fantinelli, J.C., Tournier, H., Prieto, J.M., Spegazzini, E., Debenedetti, S., et al. Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate). Food Res. Int. 2009;42(10):1403-1409.
http://dx.doi.org/10.1016/j.foodres.2009.07.004