Abstract:
The stochastic nature of biochemical processes is a source of variability that influences developmental stability. Developmental instability (DI) is often estimated through fluctuating asymmetry (FA), a parameter that deals with within-individual variation in bilateral structures. A relevant goal is to shed light on how environment, physiology and genotype relate to DI, thus providing a more comprehensive view of organismal development. Using Drosophila melanogaster isogenic lines, we investigated the effect of parental age, parental diet and offspring heterozygosity on DI. In this work, we have uncovered a clear relationship between parental age and offspring asymmetry. We show that asymmetry of the progeny increases concomitantly with parental age. Moreover, we demonstrate that enriching the diet of parents mitigates the effect of age on offspring symmetry. We show as well that increasing the heterozygosity of the progeny eliminates the effect of parental age on offspring symmetry. Taken together, our results suggest that diet, genotype and age of the parents interact to determine offspring DI in wild populations. These findings provide us with an avenue to understand the mechanisms underlying DI. ©2015 The Author(s) Published by the Royal Society. All rights reserved.
Registro:
Documento: |
Artículo
|
Título: | Parental age influences developmental stability of the progeny in Drosophila |
Autor: | Colines, B.; Rodríguez, N.C.; Hasson, E.R.; Carreira, V.; Frankel, N. |
Filiación: | Departamento de Ecología, Genética y Evolución, IEGEBA-CONICET, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón 2, Buenos Aires, 1428, Argentina
|
Palabras clave: | Developmental instability; Diet; Drosophila; Fluctuating asymmetry; Inbreeding; Parental age; age; biochemical composition; developmental biology; diet; fluctuating asymmetry; fly; genotype; heterogeneity; inbreeding; parameterization; Drosophila melanogaster |
Año: | 2015
|
Volumen: | 282
|
Número: | 1803
|
DOI: |
http://dx.doi.org/10.1098/rspb.2014.2437 |
Título revista: | Proceedings of the Royal Society B: Biological Sciences
|
Título revista abreviado: | Proc. R. Soc. B Biol. Sci.
|
ISSN: | 09628452
|
CODEN: | PRLBA
|
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09628452_v282_n1803_p_Colines |
Referencias:
- Hochachka, P.W., Somero, G.N., (2002) Biochemical Adaptation: Mechanism and Process in Physiological Evolution, , Oxford, UK: Oxford University Press
- Angilletta, M.J., (2009) Thermal Adaptation: A Theoretical and Empirical Synthesis, , Oxford, UK: Oxford University Press
- Waddington, C.H., Canalization of development and genetic assimilation of acquired characters (1959) Nature, 183, pp. 1654-1655
- Frankel, N., Davis, G.K., Vargas, D., Wang, S., Payre, F., Stern, D.L., Phenotypic robustness conferred by apparently redundant transcriptional enhancers (2010) Nature, 466, pp. 490-493
- Li, X., Cassidy, J.J., Reinke, C.A., Fischboeck, S., Carthew, R.W., A microRNA imparts robustness against environmental fluctuation during development (2009) Cell, 137, pp. 273-282
- Taipale, M., Jarosz, D.F., Lindquist, S., HSP90 at the hub of protein homeostasis: Emerging mechanistic insights (2010) Nat. Rev. Mol. Cell Biol, 11, pp. 515-528
- Debat, V., David, P., Mapping phenotypes: Canalization, plasticity and developmental stability. (2001) Trends Ecol. Evol, 16, pp. 555-561
- Debat, V., Peronnet, F., Asymmetric flies: The control of developmental noise in Drosophila (2013) Fly, 7, pp. 70-77
- Klingenberg, C.P., Developmental instability as a research tool: Using patterns of fluctuating asymmetry to infer the developmental origins of morphological integration (2003) Developmental Instability: Causes and Consequences, pp. 427-442. , (ed. M Polak, New York, NY: Oxford University Press
- Debat, V., Debelle, A., Dworkin, I., Plasticity, canalization, and developmental stability of the Drosophila wing: Joint effects of mutations and developmental temperature (2009) Evolution, 63, pp. 2864-2876
- Dongen, S.V., Fluctuating asymmetry and developmental instability in evolutionary biology: Past, present and future (2006) J. Evol. Biol, 19, pp. 1727-1743
- Bjorksten, T.A., Fowler, K., Pomiankowski, A., What does sexual trait FA tell us about stress? (2000) Trends Ecol. Evol, 15, pp. 163-166
- Leamy, L.J., Klingenberg, C.P., The genetics and evolution of fluctuating asymmetry (2005) Annu. Rev. Ecol. Evol. Syst, 36, pp. 1-21
- Alibert, P., Auffray, J., Genomic coadaptation, outbreeding depression, and developmental instability (2003) Developmental Instability: Causes and Consequences, pp. 116-134. , (ed. M Polak, New York, NY: Oxford University Press
- Pertoldi, C., Kristensen, T.N., Ersen, D.H., Loeschcke, V., Developmental instability as an estimator of genetic stress (2006) Heredity, 96, pp. 122-127
- Moller, A.P., A review of developmental instability, parasitism and disease (2006) Infect. Genet. Evol, 6, pp. 133-140
- Beasley, D., Bonisoli-Alquati, A., Mousseau, T.A., The use of fluctuating asymmetry as a measure of environmentally induced developmental instability: A meta-analysis. Ecol (2013) Indic, 30, pp. 218-226
- Mackay, T.F., The Drosophila melanogaster genetic reference panel (2012) Nature, 482, pp. 173-178
- Falconer, D.S., Mackay, T., (1996) Introduction to Quantitative Genetics, , Harlow, UK: Longman
- Stern, D.L., The Hox gene Ultrabithorax modulates the shape and size of the third leg of Drosophila by influencing diverse mechanisms (2003) Dev. Biol, 256, pp. 355-366
- Carreira, V.P., Soto, I.M., Hasson, E., Fanara, J.J., Patterns of variation in wing morphology in the cactophilic Drosophila buzzatii and its sibling D. Koepferae (2006) J. Evol. Biol, 19, pp. 1275-1282
- Palmer, A.R., Strobeck, C., Fluctuating asymmetry analysis revisited (2003) Developmental Instability: Causes and Consequences, pp. 279-319. , (ed. M Polak, New York, NY: Oxford University Press
- Reddiex, A.J., Gosden, T.P., Bonduriansky, R., Chenoweth, S.F., Sex-specific fitness consequences of nutrient intake and the evolvability of diet preferences (2013) Am. Nat, 182, pp. 91-102
- Bass, T.M., Grandison, R.C., Wong, R., Martinez, P., Partridge, L., Piper, M.D., Optimization of dietary restriction protocols in Drosophila (2007) J. Gerontol. A, Biol. Sci. Med. Sci, 62, pp. 1071-1081
- Fontana, L., Partridge, L., Longo, V.D., Extending healthy life span: From yeast to humans (2010) Science, 328, pp. 321-326
- Polak, M., Ectoparasitism in mothers causes higher positional fluctuating asymmetry in their sons: Implications for sexual selection (1997) Am. Nat, 149, pp. 955-974
- Singh, D., Rosen, V.C., Effects of maternal body morphology, morning sickness, gestational diabetes and hypertension on fluctuating asymmetry in young women (2001) Evol. Hum. Behav, 22, pp. 373-384
- Birchler, J.A., Yao, H., Chudalayandi, S., Unraveling the genetic basis of hybrid vigor (2006) Proc. Natl Acad. Sci. USA, 103, pp. 12957-12958
- Parsons, P.A., Maternal age and developmental variability (1962) J. Exp. Biol, 39, p. 251
- Wakefield, J., Harris, K., Markow, T., Parental age and developmental stability in Drosophila melanogaster (1993) Genetica, 89, pp. 235-244
- Tatar, M., Reproductive aging in invertebrate genetic models (2010) Ann. N.Y. Acad. Sci, 1204, pp. 149-155
- Fredriksson, A., Johansson Krogh, E., Hernebring, M., Pettersson, E., Javadi, A., Almstedt, A., Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster (2012) Aging Cell, 11, pp. 634-643
- Paul, C., Robaire, B., Ageing of the male germ line (2013) Nat. Rev. Urol, 10, pp. 227-234
- Wyrobek, A.J., Eskenazi, B., Young, S., Arnheim, N., Tiemann-Boege, I., Jabs, E.W., Glaser, R.L., Evenson, D., Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm (2006) Proc. Natl Acad. Sci. USA, 103, pp. 9601-9606
- Titus, S., Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans (2013) Sci. Transl. Med, 5, p. 172ra21
- Preston, C.R., Flores, C., Engels, W.R., Age-dependent usage of double-strand-break repair pathways (2006) Curr. Biol, 16, pp. 2009-2015
- Agrawal, A.F., Wang, A.D., Increased transmission of mutations by low-condition females: Evidence for condition-dependent DNA repair (2008) Plos Biol, 6, p. e30
Citas:
---------- APA ----------
Colines, B., Rodríguez, N.C., Hasson, E.R., Carreira, V. & Frankel, N.
(2015)
. Parental age influences developmental stability of the progeny in Drosophila. Proceedings of the Royal Society B: Biological Sciences, 282(1803).
http://dx.doi.org/10.1098/rspb.2014.2437---------- CHICAGO ----------
Colines, B., Rodríguez, N.C., Hasson, E.R., Carreira, V., Frankel, N.
"Parental age influences developmental stability of the progeny in Drosophila"
. Proceedings of the Royal Society B: Biological Sciences 282, no. 1803
(2015).
http://dx.doi.org/10.1098/rspb.2014.2437---------- MLA ----------
Colines, B., Rodríguez, N.C., Hasson, E.R., Carreira, V., Frankel, N.
"Parental age influences developmental stability of the progeny in Drosophila"
. Proceedings of the Royal Society B: Biological Sciences, vol. 282, no. 1803, 2015.
http://dx.doi.org/10.1098/rspb.2014.2437---------- VANCOUVER ----------
Colines, B., Rodríguez, N.C., Hasson, E.R., Carreira, V., Frankel, N. Parental age influences developmental stability of the progeny in Drosophila. Proc. R. Soc. B Biol. Sci. 2015;282(1803).
http://dx.doi.org/10.1098/rspb.2014.2437