Levels of heparin cofactor II (HCII) activity and antigen and electrophoretic pattern were studied both in normal subjects and in type I diabetic patients with high and normal levels of glycosylated haemoglobin. There was a significant reduction in HCII activity (83±7%) in patients with high levels of glycosylated haemoglobin compared with controls (95±17%; P<0.001). However, plasma HCII antigen levels were not decreased in these patients.
| Documento: | Artículo |
| Título: | Heparin cofactor II in diabetic patients |
| Autor: | Duboscq, C.; Quintana, I.; Barros, J.; Kordich, L. |
| Filiación: | Departamento de Quimica Biologica, Fac. de Ciencias Exactas/Naturales, Universidad de Buenos Aires, Pabellon II, 1428 Buenos Aires, Argentina |
| Palabras clave: | crossed immunoelectrophoresis; diabetes; heparin cofactor II; glycosylated hemoglobin; heparin cofactor II; adult; article; controlled study; diabetes mellitus; female; human; immunoassay; major clinical study; male; priority journal |
| Año: | 1994 |
| Volumen: | 5 |
| Número: | 2 |
| Página de inicio: | 201 |
| Página de fin: | 204 |
| DOI: | http://dx.doi.org/10.1097/00001721-199404000-00007 |
| Título revista: | Blood Coagulation and Fibrinolysis |
| Título revista abreviado: | BLOOD COAGUL. FIBRINOLYSIS |
| ISSN: | 09575235 |
| CODEN: | BLFIE |
| CAS: | glycosylated hemoglobin, 9062-63-9; heparin cofactor II, 81604-65-1 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09575235_v5_n2_p201_Duboscq |
