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Abstract:

The carbocyclic compound (4R,5R)-(-)-3-[(benzyloxy)methyl]-4,5-O- isopropylidene-2-cyclopentenone 1 is an important synthetic intermediate to access a variety of carbanucleosides. Herein, synthetic studies that lead to this valuable compound employing inexpensive d-ribose as the chiral source are presented. © 2004 Elsevier Ltd. All rights reserved.

Registro:

Documento: Artículo
Título:Synthetic studies toward the preparation of (4R,5R)-(-)-3-[(benzyloxy) methyl]-4,5-O-isopropylidene-cyclopenten-2-one: An important synthetic intermediate for carbanucleosides
Autor:Elhalem, E.; Comin, M.J.; Leitofuter, J.; García-Liñares, G.; Rodriguez, J.B.
Filiación:Depto. de Quím. Orgán., Fac. de Ciencias Exactas Y Naturales, Univ. Buenos Aires, Pabellon 2, C., C1428EHA Buenos Aires, Argentina
Palabras clave:3 [(benzyloxy)methyl] 4,5 o isopropylidene 2 cyclopentenone; carbocyclic nucleoside; cyclopentenone derivative; nucleoside derivative; ribose; unclassified drug; article; chirality; priority journal; synthesis
Año:2005
Volumen:16
Número:2
Página de inicio:425
Página de fin:431
DOI: http://dx.doi.org/10.1016/j.tetasy.2004.11.069
Título revista:Tetrahedron Asymmetry
Título revista abreviado:Tetrahedron Asymmetry
ISSN:09574166
CODEN:TASYE
CAS:ribose, 34466-20-1, 50-69-1, 93781-19-2
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09574166_v16_n2_p425_Elhalem

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Citas:

---------- APA ----------
Elhalem, E., Comin, M.J., Leitofuter, J., García-Liñares, G. & Rodriguez, J.B. (2005) . Synthetic studies toward the preparation of (4R,5R)-(-)-3-[(benzyloxy) methyl]-4,5-O-isopropylidene-cyclopenten-2-one: An important synthetic intermediate for carbanucleosides. Tetrahedron Asymmetry, 16(2), 425-431.
http://dx.doi.org/10.1016/j.tetasy.2004.11.069
---------- CHICAGO ----------
Elhalem, E., Comin, M.J., Leitofuter, J., García-Liñares, G., Rodriguez, J.B. "Synthetic studies toward the preparation of (4R,5R)-(-)-3-[(benzyloxy) methyl]-4,5-O-isopropylidene-cyclopenten-2-one: An important synthetic intermediate for carbanucleosides" . Tetrahedron Asymmetry 16, no. 2 (2005) : 425-431.
http://dx.doi.org/10.1016/j.tetasy.2004.11.069
---------- MLA ----------
Elhalem, E., Comin, M.J., Leitofuter, J., García-Liñares, G., Rodriguez, J.B. "Synthetic studies toward the preparation of (4R,5R)-(-)-3-[(benzyloxy) methyl]-4,5-O-isopropylidene-cyclopenten-2-one: An important synthetic intermediate for carbanucleosides" . Tetrahedron Asymmetry, vol. 16, no. 2, 2005, pp. 425-431.
http://dx.doi.org/10.1016/j.tetasy.2004.11.069
---------- VANCOUVER ----------
Elhalem, E., Comin, M.J., Leitofuter, J., García-Liñares, G., Rodriguez, J.B. Synthetic studies toward the preparation of (4R,5R)-(-)-3-[(benzyloxy) methyl]-4,5-O-isopropylidene-cyclopenten-2-one: An important synthetic intermediate for carbanucleosides. Tetrahedron Asymmetry. 2005;16(2):425-431.
http://dx.doi.org/10.1016/j.tetasy.2004.11.069