Abstract:
Essential oils obtained from eight aromatic plants of San Luis Province, Argentina, were screened for virucidal activity against herpes simplex virus type 1 (HSV-1), Junin virus (JUNV) and dengue virus type 2 (DEN-2). The most potent inhibition was observed with the essential oil of Lippia junelliana and Lippia turbinata against JUNV with virucidal concentration 50% (VC 50) values in the range 14-20 ppm, whereas Aloysia gratissima, Heterotheca latifolia and Tessaria absinthioides inhibited JUNV in the range 52-90 ppm. The virucidal activity was time- and temperature-dependent. The essential oils of A. gratissima, Artemisia douglasiana, Eupatorium patens and T. absinthioides inactivated HSV-1 at 65-125 ppm. However, only A. douglasiana and E. patens had any discernible effect on DEN-2 infectivity with VC 50 values of 60 and 150 ppm, respectively. Copyright © 2003 John Wiley & Sons, Ltd.
Registro:
Documento: |
Artículo
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Título: | Virucidal Activity of Essential Oils from Aromatic Plants of San Luis, Argentina |
Autor: | García, C.C.; Talarico, L.; Almeida, N.; Colombres, S.; Duschatzky, C.; Damonte, E.B. |
Filiación: | Departamento de Quimica Biologica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina FICES, Universidad Nacional de San Luis, San Luis, Argentina Departamento de Quimica Biologica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina
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Palabras clave: | Argentinian plants; Dengue virus; Essential oils; Herpes simplex virus; Junin virus; Virucidal activity; essential oil; plant extract; Aloysia gratissima; animal cell; antiviral activity; Argentina; aromatic plant; Artemisia; article; concentration (parameters); controlled study; cytotoxicity; dengue; Dengue virus; drug effect; drug potency; drug screening; Eupatorium patens; herpes simplex; Herpes simplex virus 1; Heterotheca latifolia; Junin virus; Lippia junelliana; Lippia turbinata; nonhuman; plant; temperature dependence; Tessaria absinthioides; time; virus inactivation; virus infection; virus inhibition; Animals; Antiviral Agents; Cercopithecus aethiops; Dengue Virus; Dose-Response Relationship, Drug; Flowers; Fruit; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Junin virus; Microbial Sensitivity Tests; Phytotherapy; Plant Leaves; Plant Oils; Plants, Medicinal; Temperature; Vero Cells; Aloysia gratissima; Artemisia; Artemisia douglasiana; Dengue virus; Dengue virus type 2; Eupatorium; Heterotheca; Heterotheca subaxillaris; Human herpesvirus 1; Junin virus; Lippia; Simplexvirus |
Año: | 2003
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Volumen: | 17
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Número: | 9
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Página de inicio: | 1073
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Página de fin: | 1075
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DOI: |
http://dx.doi.org/10.1002/ptr.1305 |
Título revista: | Phytotherapy Research
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Título revista abreviado: | Phytother. Res.
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ISSN: | 0951418X
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CODEN: | PHYRE
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CAS: | Antiviral Agents; Plant Oils
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0951418X_v17_n9_p1073_Garcia |
Referencias:
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Citas:
---------- APA ----------
García, C.C., Talarico, L., Almeida, N., Colombres, S., Duschatzky, C. & Damonte, E.B.
(2003)
. Virucidal Activity of Essential Oils from Aromatic Plants of San Luis, Argentina. Phytotherapy Research, 17(9), 1073-1075.
http://dx.doi.org/10.1002/ptr.1305---------- CHICAGO ----------
García, C.C., Talarico, L., Almeida, N., Colombres, S., Duschatzky, C., Damonte, E.B.
"Virucidal Activity of Essential Oils from Aromatic Plants of San Luis, Argentina"
. Phytotherapy Research 17, no. 9
(2003) : 1073-1075.
http://dx.doi.org/10.1002/ptr.1305---------- MLA ----------
García, C.C., Talarico, L., Almeida, N., Colombres, S., Duschatzky, C., Damonte, E.B.
"Virucidal Activity of Essential Oils from Aromatic Plants of San Luis, Argentina"
. Phytotherapy Research, vol. 17, no. 9, 2003, pp. 1073-1075.
http://dx.doi.org/10.1002/ptr.1305---------- VANCOUVER ----------
García, C.C., Talarico, L., Almeida, N., Colombres, S., Duschatzky, C., Damonte, E.B. Virucidal Activity of Essential Oils from Aromatic Plants of San Luis, Argentina. Phytother. Res. 2003;17(9):1073-1075.
http://dx.doi.org/10.1002/ptr.1305