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Abstract:

Cedrela tubiflora aqueous leaf extracts are capable of inhibiting in vitro the activity of some components of the mouse immune system related to inflammatory responses. A significant reduction in the phagocytic capability and respiratory burst response (61.5% and 57.6%, respectively) of murine peritoneal macrophages was observed when these cells were incubated for 24 h with medium containing 1 mg/mL extract. On the other hand, at a concentration of 4 mg/mL, the extract reduced significantly the phagocytic activity of mouse polymorphonuclear leukocytes (87.5%) without altering the oxidative metabolism of these cells. Finally, a concentration of 2 mg/mL was required to inhibit the haemolytic activity of both pathways of mouse complement.

Registro:

Documento: Artículo
Título:In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement
Autor:Benencia, F.; Courrèges, M.C.; Coulombié, F.C.
Filiación:Laboratory of Virology, Faculty of Science, University of Buenos Aires, 1428 Buenos Aires, Argentina
Palabras clave:Antiinflammatory activity; Cedrela tubiflora aqueous extract; Complement; Macrophages; Neutrophils; cedrela tubiflora extract; complement; plant extract; unclassified drug; aerobic metabolism; animal cell; antiinflammatory activity; article; concentration response; controlled study; hemolysis; mouse; neutrophil; nonhuman; peritoneum macrophage; phagocytosis; plant leaf; respiratory burst
Año:1996
Volumen:10
Número:1
Página de inicio:37
Página de fin:41
DOI: http://dx.doi.org/10.1002/(SICI)1099-1573(199602)10:1<37::AID-PTR770>3.0.CO;2-Z
Título revista:Phytotherapy Research
Título revista abreviado:PHYTOTHER. RES.
ISSN:0951418X
CODEN:PHYRE
CAS:complement, 9007-36-7
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0951418X_v10_n1_p37_Benencia

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Citas:

---------- APA ----------
Benencia, F., Courrèges, M.C. & Coulombié, F.C. (1996) . In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement. Phytotherapy Research, 10(1), 37-41.
http://dx.doi.org/10.1002/(SICI)1099-1573(199602)10:1<37::AID-PTR770>3.0.CO;2-Z
---------- CHICAGO ----------
Benencia, F., Courrèges, M.C., Coulombié, F.C. "In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement" . Phytotherapy Research 10, no. 1 (1996) : 37-41.
http://dx.doi.org/10.1002/(SICI)1099-1573(199602)10:1<37::AID-PTR770>3.0.CO;2-Z
---------- MLA ----------
Benencia, F., Courrèges, M.C., Coulombié, F.C. "In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement" . Phytotherapy Research, vol. 10, no. 1, 1996, pp. 37-41.
http://dx.doi.org/10.1002/(SICI)1099-1573(199602)10:1<37::AID-PTR770>3.0.CO;2-Z
---------- VANCOUVER ----------
Benencia, F., Courrèges, M.C., Coulombié, F.C. In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement. PHYTOTHER. RES. 1996;10(1):37-41.
http://dx.doi.org/10.1002/(SICI)1099-1573(199602)10:1<37::AID-PTR770>3.0.CO;2-Z