Artículo

Magdaleno, A.; Peralta Gavensky, M.; Fassiano, A.V.; Ríos de Molina, M.C.; Santos, M.; March, H.; Moretton, J.; Juárez, Á.B. "Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays" (2015) Environmental Science and Pollution Research. 22(23):19194-19202
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Abstract:

The imazethapyr herbicide (formulation Verosil ® ) was evaluated for phytotoxicity and genotoxicity using a battery of bioassays: (1) the growth inhibition of the green alga Pseudokirchneriella subcapitata, (2) the root growth and germination of the higher plant Lactuca sativa, (3) the genetic damage using the Salmonella/microsome test, and (4) the aneugenic and clastogenic effects on Allium cepa. The Verosil ® formulation was highly toxic to the non-target green alga (median effective concentration (EC50) = 1.05 ± 0.05 mg active ingredient (a.i.) L −1 ), and concentrations above 10 mg a.i. L −1 inhibited root elongation in lettuce: relative growth index (RGI) between 0.28 ± 0.01 and 0.66 ± 0.10. No genotoxic effect was observed in Salmonella typhimurium at 100 mg a.i. L −1 , either with or without the microsomal fraction. However, significant differences in the frequency of chromosomal aberrations in anaphases and telophases (bridges, chromosome fragments, and vagrants) were observed in A. cepa at concentrations between 0.01 and 1 mg a.i. L −1 with respect to the control. The frequencies of micronuclei showed significant differences with respect to the control at concentrations between 0.001 and 0.1 mg a.i. L −1 . A very high mitotic index (MI = 93.8 ± 5.8) was observed associated with a high number of cells in the prophase stage at 100 mg a.i. L −1 , indicating cytotoxicity. These results showed that imazethapyr is toxic to the non-target populations in both aquatic and terrestrial ecosystems. This herbicide might also exert clastogenic and aneugenic mitotic damage in higher plants. Therefore, the imazethapyr formulation may constitute an environmental risk to plants. © 2015, Springer-Verlag Berlin Heidelberg.

Registro:

Documento: Artículo
Título:Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays
Autor:Magdaleno, A.; Peralta Gavensky, M.; Fassiano, A.V.; Ríos de Molina, M.C.; Santos, M.; March, H.; Moretton, J.; Juárez, Á.B.
Filiación:Cátedra de Salud Pública e Higiene Ambiental, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junin 956, 4° Piso, Buenos Aires, C1113AAC, Argentina
Departamento de Química Biológica, IQUIBICEN UBA-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Departamento de Biodiversidad y Biología Experimental, IBBEA UBA-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Instituto Nacional de Tecnología Industrial (INTI), San Martín, Buenos Aires, Argentina
Agrofina S.A., Vicente López, Buenos Aires, Argentina
Palabras clave:Allium cepa; Ames test; Genotoxicity; Imazethapyr; Lactuca sativa; Pseudokirchneriella subcapitata; Toxicity; bioassay; chromosome; concentration (composition); environmental risk; genotoxicity; germination; green alga; growth response; herb; imazethapyr; inhibition; leafy vegetable; phytotoxicity; Allium cepa; Chlorophyta; Embryophyta; Lactuca; Lactuca sativa; Salmonella typhimurium; Selenastrum capricornutum; herbicide; imazethapyr; mutagenic agent; nicotinic acid derivative; water pollutant; bioassay; chromosome aberration; DNA damage; drug effects; genetics; green alga; growth, development and aging; lettuce; microbial sensitivity test; micronucleus test; mitosis; mitosis index; onion; plant root; Salmonella enterica serovar Typhimurium; toxicity; water pollutant; Biological Assay; Chlorophyta; Chromosome Aberrations; DNA Damage; Herbicides; Lettuce; Microbial Sensitivity Tests; Micronucleus Tests; Mitosis; Mitotic Index; Mutagens; Nicotinic Acids; Onions; Plant Roots; Salmonella typhimurium; Water Pollutants, Chemical
Año:2015
Volumen:22
Número:23
Página de inicio:19194
Página de fin:19202
DOI: http://dx.doi.org/10.1007/s11356-015-5103-5
Título revista:Environmental Science and Pollution Research
Título revista abreviado:Environ. Sci. Pollut. Res.
ISSN:09441344
CODEN:ESPLE
CAS:Herbicides; imazethapyr; Mutagens; Nicotinic Acids; Water Pollutants, Chemical
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09441344_v22_n23_p19194_Magdaleno

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Citas:

---------- APA ----------
Magdaleno, A., Peralta Gavensky, M., Fassiano, A.V., Ríos de Molina, M.C., Santos, M., March, H., Moretton, J.,..., Juárez, Á.B. (2015) . Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays. Environmental Science and Pollution Research, 22(23), 19194-19202.
http://dx.doi.org/10.1007/s11356-015-5103-5
---------- CHICAGO ----------
Magdaleno, A., Peralta Gavensky, M., Fassiano, A.V., Ríos de Molina, M.C., Santos, M., March, H., et al. "Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays" . Environmental Science and Pollution Research 22, no. 23 (2015) : 19194-19202.
http://dx.doi.org/10.1007/s11356-015-5103-5
---------- MLA ----------
Magdaleno, A., Peralta Gavensky, M., Fassiano, A.V., Ríos de Molina, M.C., Santos, M., March, H., et al. "Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays" . Environmental Science and Pollution Research, vol. 22, no. 23, 2015, pp. 19194-19202.
http://dx.doi.org/10.1007/s11356-015-5103-5
---------- VANCOUVER ----------
Magdaleno, A., Peralta Gavensky, M., Fassiano, A.V., Ríos de Molina, M.C., Santos, M., March, H., et al. Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays. Environ. Sci. Pollut. Res. 2015;22(23):19194-19202.
http://dx.doi.org/10.1007/s11356-015-5103-5