Artículo

Diessler, M.; Ventureira, M.; Hernandez, R.; Sobarzo, C.; Casas, L.; Barbeito, C.; Cebral, E."Differential expression and activity of matrix metalloproteinases 2 and 9 in canine early placenta" (2017) Reproduction in Domestic Animals. 52(1):35-43
Estamos trabajando para incorporar este artículo al repositorio
Consulte el artículo en la página del editor
Consulte la política de Acceso Abierto del editor

Abstract:

The zonary and endotheliochorial dog placenta is the most invasive placenta of carnivores. The importance of matrix metalloproteinases (MMP) in placenta invasiveness has been determined in several mammals including species with haemochorial, epitheliochorial and endotheliochorial placentation. Regarding the latter, the expression of MMP enzymes has been studied in the cat and the mature canine placenta. The aim of this study was to analyse the expression and activity of MMP-2 and MMP-9 in the early dog placenta. Placentae from 18 to 30 days of pregnancy were collected from four bitches. Two placentae from each bitch were analysed. Placental tissue from one uterine horn was fixed in formaldehyde for immunohistochemistry, while marginal haematoma, labyrinth, non-implantative and implantative endometrium from the contralateral horn were immediately frozen in dry ice for the analysis of MMP expression (Western blot [WB]) and activity (zymography). MMP-2 and MMP-9 were evidenced in the labyrinth, maternal glands and marginal haematoma; this finding was directly correlated with levels of MMP expression by WB, and with the activity of MMP-2, mainly in the haematoma (the area of major remodelling of tissues). Thus, although MMP-9 is well expressed in the early canine placenta, it is not active. Given the important role of MMPs for invasiveness, maternal–foetal angiogenesis and the establishment of a correct foetal nutrition, the results are consistent with the findings in other species in which the MMP-2 activation precedes the MMP-9 one in early placentation. © 2016 Blackwell Verlag GmbH

Registro:

Documento: Artículo
Título:Differential expression and activity of matrix metalloproteinases 2 and 9 in canine early placenta
Autor:Diessler, M.; Ventureira, M.; Hernandez, R.; Sobarzo, C.; Casas, L.; Barbeito, C.; Cebral, E.
Filiación:Laboratorio de Histología y Embriología Descriptiva, Experimental y Comparada (LHYEDEC), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata (UNLP), La Plata, Argentina
Laboratorio de Reproducción y Fisiopatología Materno-Embrionaria, Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Universidad de Buenos Aires (UBA)- Comisión Nacional de Investigaciones Científicas (CONICET), Facultad de Ciencias Exactas y Naturales (FCEyN)-UBA, Buenos Aires, Argentina
Instituto de Investigaciones Biomédicas (INBIOMED)-UBA/CONICET, Facultad de Medicina, UBA, Buenos Aires, Argentina
Facultad de Medicina, Instituto de Investigaciones Biomédicas (INBIOMED)-UBA/CONICET, UBA, Buenos Aires, Argentina
Small Animal Private Practice, La Plata, Argentina
Palabras clave:gelatinase A; gelatinase B; animal; dog; endometrium; female; immunohistochemistry; metabolism; placenta; pregnancy; reproduction; Animals; Dogs; Endometrium; Female; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Placenta; Placentation; Pregnancy
Año:2017
Volumen:52
Número:1
Página de inicio:35
Página de fin:43
DOI: http://dx.doi.org/10.1111/rda.12791
Handle:http://hdl.handle.net/20.500.12110/paper_09366768_v52_n1_p35_Diessler
Título revista:Reproduction in Domestic Animals
Título revista abreviado:Reprod. Domest. Anim.
ISSN:09366768
CODEN:RDANE
CAS:gelatinase A, 146480-35-5; gelatinase B, 146480-36-6; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09366768_v52_n1_p35_Diessler

Referencias:

  • Aralla, M., Groppetti, D., Caldarini, L., Cremonesi, F., Arrighi, S., Morphological evaluation of the placenta and fetal membranes during canine pregnancy from early implantation to term (2013) Research in Veterinary Science, 95, pp. 15-22
  • Barbeito, C.G., Fernández, P.E., Gimeno, E.J., Portiansky, E.L., Immunohistochemical and morphometric study of the decidual cells in the domestic cat placenta (2004) Biocell, 28, p. 229
  • Barrau, M.D., Abel, J.H., Torbit, C.A., Tietz, W.J., Development of the implantation chamber in the pregnant bitch (1975) The American Journal of Anatomy, 143, pp. 115-130
  • Beceriklisoy, H.B., Walter, I., Schäfer-Somi, S., Miller, I., Kanca, H., Izgür, H., Aslan, S., Matrix metalloproteinase (MMP)-2 and MMP-9 activity in the canine uterus before and during placentation (2007) Reproduction in Domestic Animals, 42, pp. 654-659
  • Conrad, M.L., Freitag, N., Diessler, M.E., Hernandez, R., Barrientos, G., Rose, M., Casas, L.A., Blois, S.M., Differential spatiotemporal patterns of galectin expression are a hallmark of endotheliochorial placentation (2016) American Journal of Reproductive Immunology, 75, pp. 317-325
  • Cross, J.C., Werb, Z., Fisher, S.J., Implantation and the placenta: key pieces of the development puzzle (1994) Science, 266, pp. 1508-1518
  • Deryugina, E.I., Quigley, J.P., Matrix metalloproteinases and tumor metastasis (2006) Cancer and Metastasis Reviews, 25, pp. 9-34
  • Enders, A.C., Carter, A.M., Review: The evolving placenta: Different developmental paths to a hemochorial relationship (2012) Placenta, 33, pp. S592-S598
  • Enders, A.C., Carter, A.M., The evolving placenta: Convergent evolution of variations in the endotheliochorial relationship (2012) Placenta, 33, pp. 319-326
  • Evans, H.E., Sack, W.O., Prenatal development of domestic and laboratory mammals: Growth curves, external features and selected references (1973) Zentralblatt für Veterinärmedizin, 2 (1), pp. 11-45
  • Fernández, P.E., Barbeito, C.G., Portiansky, E.L., Gimeno, E.J., Intermediate filament proteins expression and sugar moieties of the normal canine placenta (2000) Histology and Histopathology, 15, pp. 1-6
  • Fernández, P.E., Diessler, M.E., Pachame, A., Ortega, H.H., Gimeno, E.J., Portiansky, E.L., Barbeito, C.G., Intermediate filament proteins expression and carbohydrate moieties in trophoblast and decidual cells of mature cat placenta (2014) Reproduction in Domestic Animals, 49, pp. 263-269
  • Fernández, P.E., Portiansky, E.L., Barbeito, C.G., Gimeno, E.J., Characterization of cytotrophoblastic-like cells present in subinvolutioned placental sites of the bitch (1998) Histology and Histopathology, 13, pp. 995-1000
  • Gram, A., Hoffmann, B., Boos, A., Kowalewski, M.P., Expression and localization of vascular endothelial growth factor A (VEGFA) and its two receptors (VEGFR1/FLT1 and VEGFR2/FLK1/KDR) in the canine corpus luteum and utero-placental compartments during pregnancy and at normal and induced parturition (2015) General and Comparative Endocrinology, 223, pp. 54-65
  • Kautz, E., de Carvalho Papa, P., Reichler, I.M., Gram, A., Boos, A., Kowalewski, M.P., In vitro decidualisation of canine uterine stromal cells (2015) Reproductive Biology and Endocrinology, 13, p. 85
  • Kutzler, M., Sahlfeld, L., Fellows, E., Who let the dogs in: A canine trophoblast invasion model for pre-eclampsia (2012) Reproduction in Domestic Animals, 47, pp. 186-189
  • Li, C.M., Hou, L., Zhang, H., Zhang, W.Y., CCL17 Induces Trophoblast Migration and Invasion by Regulating Matrix Metalloproteinase and Integrin Expression in Human First-Trimester Placenta (2014) Reproductive Sciences, pp. 1-13
  • McGrath, K., Palis, J., Hematopoiesis in the yolk sac: More than meets the eye (2005) Experimental Hematology, 33, pp. 1021-1028
  • Merchant, S.J., Crocker, I.P., Baker, P.N., Tansinda, D., Davidge, S.T., Guilbert, L.J., Matrix metalloproteinase release from placental explants of pregnancies complicated by intrauterine growth restriction (2004) Journal of the Society for Gynecologic Investigation, 11, pp. 97-103
  • Miglino, M.A., Ambrósio, C.E., Dos Santos Martins, D., Wenceslau, C.V., Pfarrer, C., Leiser, R., The carnivore pregnancy: The development of the embryo and fetal membranes (2006) Theriogenology, 66, pp. 1699-1702
  • Nothdurft, W., Braasch, E., Calvo, W., Prummer, O., Carbonell, F., Grilli, G., Fliedner, T.M., Ontogeny of the granulocyte/macrophage progenitor cell (GM-CFC) pools in the Beagle (1984) Journal of Embryology and Experimental Morphology, 80, pp. 87-103
  • Novaro, V., Pustovrh, C., Colman-Lerner, A., Radisky, D., LoNostro, F., Paz, D., González, E., Nitricoxide induces gelatinase A (matrix metalloproteinase 2) during rat embryo implantation (2002) Fertility and Sterility, 78, pp. 1278-1287
  • Pfarrer, C., Winther, H., Leiser, R., Dantzer, V., The development of the endotheliochorial mink placenta: Light microscopy and scanning electron microscopical morphometry of maternal vascular casts (1999) Anatomy and Embryology, 199, pp. 63-74
  • Pieri, N., Souza, A.F., Casals, J.B., Roballo, K., Ambrósio, C.E., Martins, D.S., Comparative development of embryonic age by organogenesis in domestic dogs and cats (2015) Reproduction in Domestic Animals, 50, pp. 625-631
  • Riley, S.C., Leask, R., Chard, T., Wathen, N.C., Calder, A.A., Howe, D.C., Secretion of matrix metalloproteinase-2, matrix metalloproteinase-9 and tissue inhibitor of metalloproteinases into the intrauterine compartments during early pregnancy (1999) Molecular Human Reproduction, 5, pp. 376-381
  • Riley, S.C., Webb, C.J., Leask, R., McCaig, F.M., Howe, D.C., Involvement of matrix metalloproteinases 2 and 9, tissue inhibitor of metalloproteinases and apoptosis in tissue remodelling in the sheep placenta (2000) Journal of Reproduction and Fertility, 118, pp. 19-27
  • Staun-Ram, E., Goldman, S., Gabarin, D., Shalev, E., Expression and importance of matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) in human trophoblast invasion (2004) Reproductive Biology and Endocrinology, 2 (1), p. 59
  • Sternlicht, M.D., Werb, Z., How matrix metalloproteinases regulate cell behaviour (2001) Annual Review of Cell and Developmental Biology, 17, pp. 463-516
  • Stoffel, M.H., Gille, U., Friess, A.E., Scanning electron microscopy of the canine placenta (1998) Italian Journal of Anatomy and Embryology, 103, pp. 291-300
  • Takagi, M., Yamamoto, D., Ohtani, M., Miyamoto, A., Quantitative analysis of messenger RNA expression of matrix metalloproteinases(MMP-2 and MMP-9), tissue inhibitor-2 of matrix metalloproteinases (TIMP-2), and steroidogenic enzymes in bovine placentomes during gestation and postpartum (2007) Molecular Reproduction and Development, 74, pp. 801-807
  • Teesalu, T., Masson, R., Basset, P., Blasi, F., Talarico, D., Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation (1999) Developmental Dynamics, 214, pp. 248-258
  • Uekita, T., Yamanouchi, K., Sato, H., Tojo, H., Seiki, M., Tachi, C., Expression and localization of matrix metalloproteinases (MT1-MMP, MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) during synepitheliochorial placentation of goats (Capra hircus) (2004) Placenta, 25, pp. 810-819
  • Vagnoni, K.E., Ginther, O.J., Lunn, D.P., Metalloproteinase activity has a role in equine chorionic girdle cell invasion (1995) Biology of Reproduction, 53, pp. 800-805
  • Vagnoni, K.E., Zheng, J., Magness, R.R., Matrix metalloproteinases-2 and -9, and tissue inhibitor of metalloproteinases-1 of the sheep placenta during the last third of gestation (1998) Placenta, 19, pp. 447-455
  • Verstegen-Onclin, K., Verstegen, J., Endocrinology of pregnancy in the dog: A review (2008) Theriogenology, 70, pp. 291-299
  • Walter, I., Boos, A., Matrix metalloproteinases (MMP-2 and MMP-9) and tissue inhibitor-2 of matrix metalloproteinases (TIMP-2) in the placenta and interplacental uterine wall in normal cows and in cattle with retention of fetal membranes (2001) Placenta, 22, pp. 473-483
  • Walter, I., Schönkypl, S., Extracellular matrix components and matrix degrading enzymes in the feline placenta during gestation (2006) Placenta, 27, pp. 291-306
  • Wang, H., Li, Q., Shao, L., Zhu, C., Expression of matrix metalloproteinase-2, -9,-14, and tissue inhibitors of metalloproteinase-1, -2, -3 in the endometrium and placenta of rhesus monkey (Macaca mulatta) during early pregnancy (2001) Biology of Reproduction, 65, pp. 31-40
  • Wang, Z., Lu, S., Liu, C., Zhao, B., Pei, K., Tian, L., Ma, X., Expressional and epigenetic alterations of placental matrix metalloproteinase 9 in preeclampsia (2010) Gynecological Endocrinology, 26, pp. 96-102
  • Wooding, P., Burton, G., (2008) Comparative placentation: Structures, functions and evolution, pp. 169-181. , #x0026;, Berlin, Springer-Verlag
  • Xu, P., Wang, Y., Zhu, S., Luo, S., Piao, Y., Zhuang, L., Expression of matrix metalloproteinase-2, -9 and -14, tissue inhibitors of metalloproteinase-I, and matrix proteins in human placenta during the first trimester (2000) Biology of Reproduction, 62, pp. 988-994
  • Yonemoto, H., Young, C.B., Ross, J.T., Guilbert, L.L., Fairclough, R.J., Olson, D.M., Changes in matrix metalloproteinase (MMP)-2 and MMP-9 in the fetal amnion and chorion during gestation and at term and preterm labor (2006) Placenta, 27, pp. 669-677

Citas:

---------- APA ----------
Diessler, M., Ventureira, M., Hernandez, R., Sobarzo, C., Casas, L., Barbeito, C. & Cebral, E. (2017) . Differential expression and activity of matrix metalloproteinases 2 and 9 in canine early placenta. Reproduction in Domestic Animals, 52(1), 35-43.
http://dx.doi.org/10.1111/rda.12791
---------- CHICAGO ----------
Diessler, M., Ventureira, M., Hernandez, R., Sobarzo, C., Casas, L., Barbeito, C., et al. "Differential expression and activity of matrix metalloproteinases 2 and 9 in canine early placenta" . Reproduction in Domestic Animals 52, no. 1 (2017) : 35-43.
http://dx.doi.org/10.1111/rda.12791
---------- MLA ----------
Diessler, M., Ventureira, M., Hernandez, R., Sobarzo, C., Casas, L., Barbeito, C., et al. "Differential expression and activity of matrix metalloproteinases 2 and 9 in canine early placenta" . Reproduction in Domestic Animals, vol. 52, no. 1, 2017, pp. 35-43.
http://dx.doi.org/10.1111/rda.12791
---------- VANCOUVER ----------
Diessler, M., Ventureira, M., Hernandez, R., Sobarzo, C., Casas, L., Barbeito, C., et al. Differential expression and activity of matrix metalloproteinases 2 and 9 in canine early placenta. Reprod. Domest. Anim. 2017;52(1):35-43.
http://dx.doi.org/10.1111/rda.12791