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Abstract:

The values of capacitance of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylethanolamine (DMPE) monolayers on Hg, derived from cyclic voltammetry studies indicate that when the lipids are near the phase transition temperature fractures are formed at a critical area beyond that corresponding to the hydration shell of the lipids in the liquid expanded state. Similar fractures are inferred to be formed when an electric field is applied at constant area, at a breaking potential which is a function of the lipid species. These voltage values denote that energy involved in the transition induced by the electrical field is much higher for DMPE than for DMPC at low areas. This can be explained by the higher intermolecular lateral interactions by H-bonds between the ethanolamine and phosphate groups. However, at larger areas, the energy values for DMPC are as high as for DMPE which is understood to be due to the higher hydration of phosphocholine head groups. This finding gives a new insight in relation to the dynamics of the lipid head groups at the membrane interphase region in terms of the states of water between the lipids. This is congruent with previous results evaluated with the well known ΔΠ vs. surface pressure plots in monolayers of the same lipids at air-water interfaces. © 2012 Elsevier B.V.

Registro:

Documento: Artículo
Título:Water defects induced by expansion and electrical fields in DMPC and DMPE monolayers: Contribution of hydration and confined water
Autor:Almaleck, H.; Gordillo, G.J.; Disalvo, A.
Filiación:Departamento de Química Analítica y Fisicoquímica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 (1113), Buenos Aires, Argentina
Departamento de Química Inorgánica Analítica y Química Física, Facultad de Ciencias Exactas y Naturales, INQUIMAE, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón 2 (1428), Buenos Aires, Argentina
Palabras clave:Capacitance measurements; Dimyristoylphosphatidylcholine (DMPC); Dimyristoylphosphatidylethanolamine (DMPE); Head group rotation-head group hydration; Lipid monolayers; Air water interfaces; Confined water; Defects induced; Dimyristoylphosphatidylcholine; Dimyristoylphosphatidylethanolamine (DMPE); Electrical field; Energy value; Ethanolamines; H-bonds; Head groups; Hydration shell; Interphase regions; Lateral interactions; Lipid monolayer; Lipid species; Low area; Phosphate group; Phosphocholine; States of water; Surface pressures; Capacitance measurement; Cyclic voltammetry; Electric fields; Fracture; Lipids; Monolayers; Hydration; dimyristoylphosphatidylcholine; dimyristoylphosphatidylethanolamine; ethanolamine; glycerophospholipid; lipid; mercury; phosphate; unclassified drug; water; article; controlled study; cyclic potentiometry; dynamics; electric capacitance; electric field; electric potential; hydration; hydrogen bond; lipid monolayer; molecular interaction; phase transition temperature; pressure gradient; priority journal; surface property; temperature; Dimyristoylphosphatidylcholine; Lipid Bilayers; Lipids; Phosphatidylethanolamines; Temperature; Water
Año:2013
Volumen:102
Página de inicio:871
Página de fin:878
DOI: http://dx.doi.org/10.1016/j.colsurfb.2012.09.031
Título revista:Colloids and Surfaces B: Biointerfaces
Título revista abreviado:Colloids Surf. B Biointerfaces
ISSN:09277765
CODEN:CSBBE
CAS:dimyristoylphosphatidylcholine, 13699-48-4, 18194-24-6; dimyristoylphosphatidylethanolamine, 20255-95-2; ethanolamine, 141-43-5; lipid, 66455-18-3; mercury, 14302-87-5, 7439-97-6; phosphate, 14066-19-4, 14265-44-2; water, 7732-18-5; 1,2-dimyristoylphosphatidylethanolamine, 20255-95-2; Dimyristoylphosphatidylcholine, 13699-48-4; Lipid Bilayers; Lipids; Phosphatidylethanolamines; Water, 7732-18-5
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09277765_v102_n_p871_Almaleck

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Citas:

---------- APA ----------
Almaleck, H., Gordillo, G.J. & Disalvo, A. (2013) . Water defects induced by expansion and electrical fields in DMPC and DMPE monolayers: Contribution of hydration and confined water. Colloids and Surfaces B: Biointerfaces, 102, 871-878.
http://dx.doi.org/10.1016/j.colsurfb.2012.09.031
---------- CHICAGO ----------
Almaleck, H., Gordillo, G.J., Disalvo, A. "Water defects induced by expansion and electrical fields in DMPC and DMPE monolayers: Contribution of hydration and confined water" . Colloids and Surfaces B: Biointerfaces 102 (2013) : 871-878.
http://dx.doi.org/10.1016/j.colsurfb.2012.09.031
---------- MLA ----------
Almaleck, H., Gordillo, G.J., Disalvo, A. "Water defects induced by expansion and electrical fields in DMPC and DMPE monolayers: Contribution of hydration and confined water" . Colloids and Surfaces B: Biointerfaces, vol. 102, 2013, pp. 871-878.
http://dx.doi.org/10.1016/j.colsurfb.2012.09.031
---------- VANCOUVER ----------
Almaleck, H., Gordillo, G.J., Disalvo, A. Water defects induced by expansion and electrical fields in DMPC and DMPE monolayers: Contribution of hydration and confined water. Colloids Surf. B Biointerfaces. 2013;102:871-878.
http://dx.doi.org/10.1016/j.colsurfb.2012.09.031