A patient's major depression and Cotard's syndrome (the delusion of being dead) both resolved completely after 12 ECT treatments. A SPECT study 1 week before ECT showed reduced blood flow in the frontoparietal medial and dorsolateral frontal cortex, basal ganglia, and thalamus; SPECT 1 month after ECT showed perfusion increments in those regions. This case study demonstrates that Cotard's syndrome in the context of major depression may be successfully treated with ECT and suggests that the psychiatric improvement was accompanied by increased blood flow in specific brain areas.
Documento: | Artículo |
Título: | SPECT findings before and after ECT in a patient with major depression and Cotard's syndrome |
Autor: | Petracca, G.; Migliorelli, R.; Vazquez, S.; Starkstein, S.E. |
Filiación: | Department of Neuropsychiatry, Raul Carrea Inst. Neurological Res., Montaneses 2325, 1428 Buenos Aires, Argentina |
Palabras clave: | adult; article; basal ganglion; brain blood flow; case report; cotard syndrome; delusion; depression; electroconvulsive therapy; frontal cortex; frontal lobe; human; male; paranoia; priority journal; single photon emission computer tomography; thalamus |
Año: | 1995 |
Volumen: | 7 |
Número: | 4 |
Página de inicio: | 505 |
Página de fin: | 507 |
DOI: | http://dx.doi.org/10.1176/jnp.7.4.505 |
Título revista: | Journal of Neuropsychiatry and Clinical Neurosciences |
Título revista abreviado: | J. NEUROPSYCHIATRY CLIN. NEUROSCI. |
ISSN: | 08950172 |
CODEN: | JNCNE |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_08950172_v7_n4_p505_Petracca |