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Abstract:

Responsive interfacial architectures of practical interest commonly require the combination of conflicting properties in terms of their demand upon material structure. Switchable stiffness, wettability, and permeability, key features for tissue engineering applications, are in fact known to be exclusively interdependent. Here, we present a nanoarchitectonic approach that decouples these divergent properties by the use of thermoresponsive microgels as building blocks for the construction of three-dimensional arrays of interconnected pores. Layer-by-layer assembled poly(N-isopropylacrylamide-co-methacrylic acid) microgel films were found to exhibit an increase in hydrophobicity, stiffness, and adhesion properties upon switching the temperature from below to above the lower critical solution temperature, whereas the permeability of redox probes through the film remained unchanged. Our findings indicate that the switch in hydrophilicity and nanomechanical properties undergone by the microgels does not compromise the porosity of the film, thus allowing the free diffusion of redox probes through the polymer-free volume of the submicrometer pores. This novel approach for decoupling conflicting properties provides a strategic route for creating tailorable scaffolds with unforeseen functionalities. © 2018 American Chemical Society.

Registro:

Documento: Artículo
Título:Layer-by-Layer Assembled Microgels Can Combine Conflicting Properties: Switchable Stiffness and Wettability without Affecting Permeability
Autor:Maza, E.; Von Bilderling, C.; Cortez, M.L.; Díaz, G.; Bianchi, M.; Pietrasanta, L.I.; Giussi, J.M.; Azzaroni, O.
Filiación:Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de la Plata (UNLP), Diagonal 113 y 64 s/n, La Plata, Buenos Aires, 1900, Argentina
Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, C1428EHA, Argentina
Instituto de Física de Buenos Aires (IFIBA, UBA-CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, C1428EHA, Argentina
Centro de Microscopías Avanzadas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, C1428EHA, Argentina
Palabras clave:Acrylic monomers; Probes; Stiffness; Tissue engineering; Wetting; Adhesion properties; Interconnected pores; Interfacial architecture; Lower critical solution temperature; N- isopropylacrylamide; Nanomechanical property; Three dimensional arrays; Tissue engineering applications; Gels
Año:2018
Volumen:34
Número:12
Página de inicio:3711
Página de fin:3719
DOI: http://dx.doi.org/10.1021/acs.langmuir.8b00047
Título revista:Langmuir
Título revista abreviado:Langmuir
ISSN:07437463
CODEN:LANGD
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07437463_v34_n12_p3711_Maza

Referencias:

  • McKee, J.R., Appel, E.A., Seitsonen, J., Kontturi, E., Scherman, O.A., Ikkala, O., Healable, Stable and Stiff Hydrogels: Combining Conflicting Properties Using Dynamic and Selective Three-Component Recognition with Reinforcing Cellulose Nanorods (2014) Adv. Funct. Mater., 24, pp. 2706-2713
  • Watanabe, H., Vendamme, R., Kunitake, T., Development of Fabrication of Giant Nanomembranes (2007) Bull. Chem. Soc. Jpn., 80, pp. 433-440
  • Gwag, J.S., Kim, Y.-K., Lee, Y.-J., Baek, J.-H., Kim, J.-H., Anchoring Competition on Nanosurface Boundaries with Conflicting Mixed Nematic Anchoring Properties (2012) Jpn. J. Appl. Phys., 51. , 034102 10.7567/JJAP.51.034102
  • Kamperman, M., Synytska, A., Switchable Adhesion by Chemical Functionality and Topography (2012) J. Mater. Chem., 22, pp. 19390-19401
  • Synytska, A., Svetushkina, E., Puretskiy, N., Stoychev, G., Berger, S., Ionov, L., Bellmann, C., Stamm, M., Biocompatible Polymeric Materials with Switchable Adhesion Properties (2010) Soft Matter, 6, pp. 5907-5914
  • Hammer, D.A., Tirrell, M., Biological Adhesion at Interfaces (1996) Annu. Rev. Mater. Sci., 26, pp. 651-691
  • Mager, M.D., Lapointe, V., Stevens, M.M., Exploring and Exploiting Chemistry at the Cell Surface (2011) Nat. Chem., 3, pp. 582-589
  • Skorb, E.V., Andreeva, D.V., Surface Nanoarchitecture for Bio-Applications: Self-Regulating Intelligent Interfaces (2013) Adv. Funct. Mater., 23, pp. 4483-4506
  • Sniadecki, N.J., Desai, R.A., Ruiz, S.A., Chen, C.S., Nanotechnology for Cell-Substrate Interactions (2006) Ann. Biomed. Eng., 34, pp. 59-74
  • Tang, Z., Wang, Y., Podsiadlo, P., Kotov, N.A., Biomedical Applications of Layer-by-Layer Assembly: From Biomimetics to Tissue Engineering (2006) Adv. Mater., 18, pp. 3203-3224
  • Yamato, M., Akiyama, Y., Kobayashi, J., Yang, J., Kikuchi, A., Okano, T., Temperature-Responsive Cell Culture Surfaces for Regenerative Medicine with Cell Sheet Engineering (2007) Prog. Polym. Sci., 32, pp. 1123-1133
  • Guest, J.K., Prévost, J.H., Optimizing Multifunctional Materials: Design of Microstructures for Maximized Stiffness and Fluid Permeability (2006) Int. J. Solids Struct., 43, pp. 7028-7047
  • Jaber, J.A., Schlenoff, J.B., Polyelectrolyte Multilayers with Reversible Thermal Responsivity (2005) Macromolecules, 38, pp. 1300-1306
  • Lehaf, A.M., Moussallem, M.D., Schlenoff, J.B., Correlating the Compliance and Permeability of Photo-Cross-Linked Polyelectrolyte Multilayers (2011) Langmuir, 27, pp. 4756-4763
  • García, T.A., Gervasi, C.A., Rodríguez Presa, M.J., Otamendi, J.I., Moya, S.E., Azzaroni, O., Molecular Transport in Thin Thermoresponsive poly(N -Isopropylacrylamide) Brushes with Varying Grafting Density (2012) J. Phys. Chem. C, 116, pp. 13944-13953
  • Song, S., Hu, N., "on-Off" switchable Bioelectrocatalysis Synergistically Controlled by Temperature and Sodium Sulfate Concentration Based on poly(N -Isopropylacrylamide) Films (2010) J. Phys. Chem. B, 114, pp. 5940-5945
  • Prokopović, V.Z., Duschl, C., Volodkin, D.V., Hyaluronic Acid/poly-L-Lysine Multilayers Coated with Gold Nanoparticles: Cellular Response and Permeability Study (2014) Polym. Adv. Technol., 25, pp. 1342-1348
  • Chen, Y., Zhou, S., Li, Q., Computational Design for Multifunctional Microstructural Composites (2009) Int. J. Mod. Phys. B, 23, pp. 1345-1351
  • Ariga, K., Li, J., Nanoarchitectonics for Advanced Materials: Strategy beyond Nanotechnology (2016) Adv. Mater., 28, pp. 987-988
  • Aono, M., Bando, Y., Ariga, K., Nanoarchitectonics: Pioneering a New Paradigm for Nanotechnology in Materials Development (2012) Adv. Mater., 24, pp. 150-151
  • Ariga, K., Malgras, V., Ji, Q., Zakaria, M.B., Yamauchi, Y., Coordination Nanoarchitectonics at Interfaces between Supramolecular and Materials Chemistry (2016) Coord. Chem. Rev., 320-321, pp. 139-152
  • Ariga, K., Ji, Q., Hill, J.P., Bando, Y., Aono, M., Forming Nanomaterials as Layered Functional Structures toward Materials Nanoarchitectonics (2012) NPG Asia Mater., 4. , e17 10.1038/am.2012.30
  • Serpe, M.J., Jones, C.D., Lyon, L.A., Layer-by-Layer Deposition of Thermoresponsive Microgel Thin Films (2003) Langmuir, 19, pp. 8759-8764
  • Nolan, C.M., Serpe, M.J., Lyon, L.A., Thermally Modulated Insulin Release from Microgel Thin Films (2004) Biomacromolecules, 5, pp. 1940-1946
  • Serpe, M.J., Lyon, L.A., Optical and Acoustic Studies of pH-Dependent Swelling in Microgel Thin Films (2004) Chem. Mater., 16, pp. 4373-4380
  • Clarke, K.C., Lyon, L.A., Modulation of the Deswelling Temperature of Thermoresponsive Microgel Films (2013) Langmuir, 29, pp. 12852-12857
  • Zhang, L., Spears, M.W., Lyon, L.A., Tunable Swelling and Rolling of Microgel Membranes (2014) Langmuir, 30, pp. 7628-7634
  • Höfl, S., Zitzler, L., Hellweg, T., Herminghaus, S., Mugele, F., Volume Phase Transition of "smart" Microgels in Bulk Solution and Adsorbed at an Interface: A Combined AFM, Dynamic Light, and Small Angle Neutron Scattering Study (2007) Polymer, 48, pp. 245-254
  • Schmidt, S., Motschmann, H., Hellweg, T., Von Klitzing, R., Thermoresponsive Surfaces by Spin-Coating of PNIPAM-Co-PAA Microgels: A Combined AFM and Ellipsometry Study (2008) Polymer, 49, pp. 749-756
  • Decher, G., Hong, J.-D., Buildup of Ultrathin Multilayer Films by a Self-Assembly Process, 1 Consecutive Adsorption of Anionic and Cationic Bipolar Amphiphiles on Charged Surfaces (1991) Makromol. Chem., Macromol. Symp., 46, pp. 321-327
  • Decher, G., Hong, J.D., Schmitt, J., Buildup of Ultrathin Multilayer Films by a Self-Assembly Process: III. Consecutively Alternating Adsorption of Anionic and Cationic Polyelectrolytes on Charged Surfaces (1992) Thin Solid Films, 210-211, pp. 831-835
  • Schmidt, S., Hellweg, T., Von Klitzing, R., Von. Packing Density Control in P (NIPAM-Co-AAc) Microgel Monolayers: Effect of Surface Charge, pH, and Preparation Technique (2008) Langmuir, 24, pp. 12595-12602
  • Nerapusri, V., Keddie, J.L., Vincent, B., Bushnak, I.A., Swelling and Deswelling of Adsorbed Microgel Monolayers Triggered by Changes in Temperature, pH, and Electrolyte Concentration (2006) Langmuir, 22, pp. 5036-5041
  • Chyasnavichyus, M., Young, S.L., Tsukruk, V.V., Mapping Micromechanical Properties of Soft Polymer Contact Lenses (2014) Polymer, 55, pp. 6091-6101
  • Giussi, J.M., Velasco, M.I., Longo, G.S., Acosta, R.H., Azzaroni, O., Unusual Temperature-Induced Swelling of Ionizable poly(N-Isopropylacrylamide)-Based Microgels: Experimental and Theoretical Insights into Its Molecular Origin (2015) Soft Matter, 11, pp. 8879-8886
  • Schmidt, S., Zeiser, M., Hellweg, T., Duschl, C., Fery, A., Möhwald, H., Adhesion and Mechanical Properties of PNIPAM Microgel Films and Their Potential Use as Switchable Cell Culture Substrates (2010) Adv. Funct. Mater., 20, pp. 3235-3243
  • Vanlandingham, M.R., McKnight, S.H., Palmese, G.R., Elings, J.R., Huang, X., Bogetti, T.A., Eduljee, R.F., Gillespie, J.W., Nanoscale Indentation of Polymer Systems Using the Atomic Force Microscope (1997) J. Adhes., 64, pp. 31-59
  • Overney, R.M., Nanotribological Studies on Polymers (1995) Trends Polym. Sci., 3, pp. 359-364
  • Shulha, H., Kovalev, A., Myshkin, N., Tsukruk, V.V., Some Aspects of AFM Nanomechanical Probing of Surface Polymer Films (2004) Eur. Polym. J., 40, pp. 949-956
  • LeMieux, M.C., Lin, Y.H., Cuong, P.D., Ahn, H.S., Zubarev, E.R., Tsukruk, V.V., Microtribological and Nanomechanical Properties of Switchable Y-Shaped Amphiphilic Polymer Brushes (2005) Adv. Funct. Mater., 15, pp. 1529-1540
  • LeMieux, M.C., Peleshanko, S., Anderson, K.D., Tsukruk, V.V., Adaptive Nanomechanical Response of Stratified Polymer Brush Structures (2007) Langmuir, 23, pp. 265-273
  • Ye, C., Drachuk, I., Calabrese, R., Dai, H., Kaplan, D.L., Tsukruk, V.V., Permeability and Micromechanical Properties of Silk Ionomer Microcapsules (2012) Langmuir, 28, pp. 12235-12244
  • Chizhik, S.A., Huang, Z., Gorbunov, V.V., Myshkin, N.K., Tsukruk, V.V., Micromechanical Properties of Elastic Polymeric Materials as Probed by Scanning Force Microscopy (1998) Langmuir, 14, pp. 2606-2609
  • FitzGerald, P.A., Dupin, D., Armes, S.P., Wanless, E.J., In Situ Observations of Adsorbed Microgel Particles (2007) Soft Matter, 3, pp. 580-586
  • Woodward, N.C., Snowden, M.J., Chowdhry, B.Z., Jenkins, P., Larson, I., Measurement of the Interaction Forces between Poly(N-Isopropylacrylamide-acrylic Acid) Microgel and Silica Surfaces by Colloid Probe Microscopy (2002) Langmuir, 18, pp. 2089-2095
  • Cole, M.A., Voelcker, N.H., Thissen, H., Horn, R.G., Griesser, H.J., Colloid Probe AFM Study of Thermal Collapse and Protein Interactions of poly(N-Isopropylacrylamide) Coatings (2010) Soft Matter, 6, pp. 2657-2667
  • Kidoaki, S., Ohya, S., Nakayama, Y., Matsuda, T., Thermoresponsive Structural Change of a poly(N-Isopropylacrylamide) Graft Layer Measured with an Atomic Force Microscope (2001) Langmuir, 17, pp. 2402-2407
  • Cho, E.C., Yong, D.K., Cho, K., Temperature-Dependent Intermolecular Force Measurement of poly(N-Isopropylacrylamide) Grafted Surface with Protein (2005) J. Colloid Interface Sci., 286, pp. 479-486
  • Kobayashi, J., Anson, F.C., Association of Electroactive Counterions with Polyelectrolytes. 2. Comparison of Electrostatic and Coordinative Bonding to a Mixed Polycation-Polypyridine (1991) J. Phys. Chem., 95, pp. 2595-2601

Citas:

---------- APA ----------
Maza, E., Von Bilderling, C., Cortez, M.L., Díaz, G., Bianchi, M., Pietrasanta, L.I., Giussi, J.M.,..., Azzaroni, O. (2018) . Layer-by-Layer Assembled Microgels Can Combine Conflicting Properties: Switchable Stiffness and Wettability without Affecting Permeability. Langmuir, 34(12), 3711-3719.
http://dx.doi.org/10.1021/acs.langmuir.8b00047
---------- CHICAGO ----------
Maza, E., Von Bilderling, C., Cortez, M.L., Díaz, G., Bianchi, M., Pietrasanta, L.I., et al. "Layer-by-Layer Assembled Microgels Can Combine Conflicting Properties: Switchable Stiffness and Wettability without Affecting Permeability" . Langmuir 34, no. 12 (2018) : 3711-3719.
http://dx.doi.org/10.1021/acs.langmuir.8b00047
---------- MLA ----------
Maza, E., Von Bilderling, C., Cortez, M.L., Díaz, G., Bianchi, M., Pietrasanta, L.I., et al. "Layer-by-Layer Assembled Microgels Can Combine Conflicting Properties: Switchable Stiffness and Wettability without Affecting Permeability" . Langmuir, vol. 34, no. 12, 2018, pp. 3711-3719.
http://dx.doi.org/10.1021/acs.langmuir.8b00047
---------- VANCOUVER ----------
Maza, E., Von Bilderling, C., Cortez, M.L., Díaz, G., Bianchi, M., Pietrasanta, L.I., et al. Layer-by-Layer Assembled Microgels Can Combine Conflicting Properties: Switchable Stiffness and Wettability without Affecting Permeability. Langmuir. 2018;34(12):3711-3719.
http://dx.doi.org/10.1021/acs.langmuir.8b00047