Navegar

Colección

Datos Estadísticas

Artículo

La versión final de este artículo es de uso interno. El editor solo permite incluir en el repositorio el artículo en su versión post-print. Por favor, si usted la posee enviela a
Consulte el artículo en la página del editor
Consulte la política de Acceso Abierto del editor

Abstract:

Rational construction of interfaces based on multicomponent responsive systems in which molecular transport is mediated by structures of nanoscale dimensions has become a very fertile research area in biomimetic supramolecular chemistry. Herein, we describe the creation of hybrid mesostructured interfaces with reversible gate-like transport properties that can be controlled by chemical inputs, such as protons or calcium ions. This was accomplished by taking advantage of the surface-initiated polymerization of 2-(methacryloyloxy) ethyl phosphate (MEP) monomer units into and onto mesoporous silica thin films. In this way, phosphate-bearing polymer brushes were used as " gatekeepers" located not only on the outer surface of mesoporous thin films but also in the inner environment of the porous scaffold. Pore-confined PMEP brushes respond to the external triggering chemical signals not only by altering their physicochemical properties but also by switching the transport properties of the mesoporous film. The ion-gate response/operation was based on the protonation and/or chelation of phosphate monomer units in which the polymer brush works as an off-on switch in response to the presence of protons or Ca 2+ ions. The hybrid meso-architectured interface and their functional features were studied by acombination of experimental techniques including ellipso-porosimetry, cyclic voltammetry, X-ray reflectivity, grazing incidence small-angle X-ray scattering, X-ray photoelectron spectroscopy, and in situ atomic force microscopy. In this context, we believe that the integration of stimuli-responsive polymer brushes into nanoscopic supramolecular architectures would provide new routes toward multifunctional biomimetic nanosystems displaying transport properties similar to those encountered in biological ligand-gated ion channels. © 2012 American Chemical Society.

Registro:

Documento: Artículo
Título:Proton and calcium-gated ionic mesochannels: Phosphate-bearing polymer brushes hosted in mesoporous thin films as biomimetic interfacial architectures
Autor:Brunsen, A.; Díaz, C.; Pietrasanta, L.I.; Yameen, B.; Ceolín, M.; Soler-Illia, G.J.A.A.; Azzaroni, O.
Filiación:Gerencia Química, Comisión Nacional de Energía Atómica (CNEA), Argentina
Centro de Microscopías Avanzadas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina
Max-Planck-Institut für Polymerforschung, Mainz, Germany
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Departamento de Química, CONICET, Argentina
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), C1033AAJ Buenos Aires, Argentina
Palabras clave:Calcium ions; Chemical signals; Experimental techniques; Functional features; Grazing incidence small-angle X-ray scattering; In-situ; Interfacial architecture; Ligand-gated ion channels; Mesochannels; Mesoporous films; Mesoporous silica thin films; Mesoporous thin films; Mesostructured; Molecular transport; Monomer units; Multicomponents; Nanoscale dimensions; Outer surface; Phosphate monomers; Physicochemical property; Polymer brushes; Porous scaffold; Rational construction; Stimuli-responsive polymer; Supramolecular architectures; Surface initiated polymerization; X ray reflectivity; Atomic force microscopy; Biomimetics; Cyclic voltammetry; Ions; Mesoporous materials; Monomers; Nanosystems; Phosphate deposits; Photoelectrons; Protons; Scaffolds; Supramolecular chemistry; Thin films; Transport properties; X ray photoelectron spectroscopy; Functional polymers; biomimetic material; calcium; ligand gated ion channel; nanomaterial; phosphate; polymer; proton; article; artificial membrane; biomimetics; chemistry; methodology; porosity; Biomimetic Materials; Biomimetics; Calcium; Ligand-Gated Ion Channels; Membranes, Artificial; Nanostructures; Phosphates; Polymers; Porosity; Protons
Año:2012
Volumen:28
Número:7
Página de inicio:3583
Página de fin:3592
DOI: http://dx.doi.org/10.1021/la204854r
Título revista:Langmuir
Título revista abreviado:Langmuir
ISSN:07437463
CODEN:LANGD
CAS:calcium, 14092-94-5, 7440-70-2; phosphate, 14066-19-4, 14265-44-2; proton, 12408-02-5, 12586-59-3; Calcium, 7440-70-2; Ligand-Gated Ion Channels; Membranes, Artificial; Phosphates; Polymers; Protons
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07437463_v28_n7_p3583_Brunsen

Referencias:

  • Fu, Q., Rao, G.V.R., Ista, L.K., Wu, Y., Andrzejewski, B.P., Sklar, L.A., Ward, T.L., López, G.P., (2003) Adv. Mater., 15, p. 1262
  • Park, M.-K., Deng, S., Advincula, R.C., (2004) J. Am. Chem. Soc., 126, p. 13723
  • Fu, Q., Rama Rao, G.V., Ward, T.L., Lu, Y., López, G.P., (2007) Langmuir, 23, p. 170
  • Tam, T.K., Pita, M., Motornov, M., Tokarev, I., Minko, S., Katz, E., (2010) Adv. Mater., 22, p. 1863
  • Aguilella, V., Kontturi, K., Murtomaki, L., Ramírez, P., (1994) J. Controlled Release, 32, p. 249
  • Rojanasakul, Y., Robinson, J.R., (1989) Int. J. Pharm., 55, p. 237
  • Brunsen, A., Cui, J., Ceolín, M., Del Campo, A., Soler-Illia, G.J.A.A., Azzaroni, O., (2012) Chem. Commun., 48, pp. 1422-1424
  • Aznar, E., Marcos, M.A., Martínez-Máñez, R., Sancenón, F., Soto, J., Amorós, P., Guillem, C., (2009) J. Am. Chem. Soc., 131, p. 6833
  • Martínez-Máñez, R., Sancenón, F., Hecht, M., Biyikal, M., Rurack, K., (2011) Anal. Bioanal. Chem., 399, p. 55
  • Aznar, E., Casasús, R., García-Acosta, B., Marcos, M.D., Martínez-Máñez, R., Sancenón, F., Soto, J., Amorós, P., (2007) Adv. Mater., 19, p. 2228
  • Liu, N., Dunphy, D.R., Atanassov, P., Bunge, S.D., Chen, Z., López, G.P., Boyle, T.J., Brinker, C.J., (2004) Nano Lett., 4, p. 551
  • Angelos, S., Yang, Y.-W., Khashab, N.M., Stoddart, J.F., Zink, J.I., (2009) J. Am. Chem. Soc., 131, p. 11344
  • Ito, Y., Inaba, M., Chung, D.-J., Imanishi, Y., (1992) Macromolecules, 25, pp. 7313-7316
  • Park, Y.S., Ito, Y., Imanishi, Y., (1997) Chem. Mater., 9, pp. 2755-2758
  • Ito, Y., Ochiai, Y., Park, Y.S., Imanishi, Y., (1997) J. Am. Chem. Soc., 119, pp. 1619-1623
  • Fan, R., Huh, S., Yan, R., Arnold, J., Yang, P., (2008) Nat. Mater., 7, pp. 303-307
  • Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B.T., MacKinnon, R., (2002) Nature, 417, p. 515
  • Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B.T., MacKinnon, R., (2002) Nature, 417, p. 523
  • Hille, B., (2011) Ion Channels of Excitable Membranes, , 3rd ed.; Sinauer Associates: Sunderland U.K
  • Rurack, K., Martínez-Máñez, R., (2010) The Supramolecular Chemistry of Organic-Inorganic Hybrid Materials, , John Wiley & Sons: Hoboken
  • Descalzo, A.B., Martínez-Máñez, R., Sancenón, F., Hoffmann, K., Rurack, K., (2006) Angew. Chem. Int. Ed., 45, p. 5924
  • Chung, S.-H., Anderson, O.S., Krishnamurthy, V.V., (2010) Biological Membrane Ion Channels: Dynamics, Structure, and Applications, , Springer-Verlag: Heidelberg
  • Kew, J., Davies, C., (2010) Ion Channels: From Structure to Function, , Oxford University Press: Oxford
  • Soler-Illia, G.J.A.A., Innocenzi, P., (2006) Chem.-Eur. J., 12, p. 4478
  • Barbey, R., Lavanant, L., Paripovic, D., Schüwer, N., Sugnaux, C., Tugulu, S., Klok, H.-A., (2009) Chem. Rev., 109, p. 5437
  • Advincula, R. C., Brittain, W. J., Caster, K. C., Rühe, J., Eds.; Wiley- VCH: Weinheim, Germany, 2004; Azzaroni, O., Brown, A.A., Huck, W.T.S., (2006) Angew. Chem. Int. Ed., 45, p. 1770
  • Advincula, R.C., (2006) Surface-Initiated Polymerization, p. 107. , I; Jordan, R., Ed.; Springer-Verlag: Heidelberg
  • Calvo, A., Yameen, B., Williams, F.J., Soler-Illia, G.J.A.A., Azzaroni, O., (2009) J. Am. Chem. Soc., 131, p. 10866
  • Soler-Illia, G.J.A.A., Azzaroni, O., (2011) Chem. Soc. Rev., 40, p. 1107
  • Casasús, R., Marcos, M.D., Martínez-Máñez, R., Ros-Lis, J.V., Soto, J., Villaescusa, L.A., Amorós, P., Latorre, J., (2004) J. Am. Chem. Soc., 126, p. 8612
  • Casasús, R., Climent, E., Marcos, M.A., Martínez- Máñez, R., Sancenón, F., Soto, J., Amorós, P., Ruiz, E., (2008) J. Am. Chem. Soc., 130, p. 1903
  • Angelatos, A.S., Wang, Y., Caruso, F., (2008) Langmuir, 24, p. 4224
  • Wang, Y., Angelatos, A.S., Dunstan, D.E., Caruso, F., (2007) Macromolecules, 40, p. 7594
  • Wang, Y., Caruso, F., (2006) Chem. Mater., 18, p. 4089
  • Wang, Y., Bansal, V., Zelikin, A.N., Caruso, F., (2008) Nano Lett., 8, p. 1741
  • Yameen, B., Ali, M., Neumann, R., Ensinger, W., Knoll, W., Azzaroni, O., (2010) Chem. Commun., 46, p. 1908
  • Walcarius, A., (2010) Anal. Bioanal. Chem., 396, p. 261
  • Hutter, J.L., Bechhoefer, J., (1993) Rev. Sci. Instrum., 64, p. 1868
  • Ducker, W.A., Senden, T.J., Pashley, R.M., (1992) Langmuir, 8, p. 1831
  • Soler-Illia, G.J.A.A., Sanchez, C., Lebeau, B., (2002) Patarin J. Chem. Rev., 102, p. 4093
  • Boissiére, C., Grosso, D., Lepoutre, S., Nicole, L., Brunet-Bruneau, A., Sanchez, C., (2005) Langmuir, 21, p. 12362
  • Kim, T.-W., Ryoo, R., Kruk, K., Gierszal, K.P., Jaroniec, M., Kamiya, S., Terasaki, O., (2004) J. Phys. Chem. B, 108, pp. 11480-11489
  • Brunsen, A., Calvo, A., Williams, F.J., Soler-Illia, G.J.A.A., Azzaroni, O., (2011) Langmuir, 27, p. 4328
  • Calvo, A., Yameen, Y., Williams, F.J., Azzaroni, O., Soler-Illia, G.J.A.A., (2009) Chem Commun., 2553
  • Gibaud, A., Hazra, S., (2000) Curr. Sci., 78, p. 1467
  • Calvo, A., Fuertes, M.C., Yameen, B., Williams, F.J., Azzaroni, O., Soler-Illia, G.J.A.A., (2010) Langmuir, 26, p. 5559
  • Dourdain, S., Mehdi, A., Bardeau, J.F., Gibaud, A., (2006) Thin Solid Films, 495, pp. 205-209
  • Pinto, L.H., Holsinger, L.J., Lamb, R.A., (1992) Cell, 69, pp. 517-528
  • Kass, I., Arkin, I.T., (2005) Structure, 13, pp. 1789-1798
  • Okada, A., Miura, T., Takeuchi, H., (2001) Biochemistry, 40, p. 6053
  • Takeuchi, H., Okada, A., Miura, T., (2003) FEBS Lett., 552, p. 35
  • Etienne, M., Quach, A., Grosso, D., Nicole, L., Sanchez, C., Walcarius, A., (2007) Chem. Mater., 19, p. 844
  • Fattakhova-Rohlfing, D., Wark, M., Rathousky, J., (2007) Chem. Mater., 19, p. 1640
  • Zhang, J., Kirkham, J., Robinson, C., Wallwork, M.L., Smith, D.A., Marsh, A., Wong, M., (2000) Anal. Chem., 72, p. 1973
  • Zhou, F., Huck, W.T.S., (2005) Chem. Commun., 5999
  • Rapuano, R., Carmona-Ribeiro, A.M., (1997) J. Colloid Interface Sci., 193, p. 104
  • Mercier, P., Savoie, R., (1997) Biospectroscopy, 3, p. 299
  • Murray, D.K., (2010) J. Colloid Interface Sci., 352, p. 163
  • Murray, D.K., Harrison, J.C., Wallace, W.E.J., (2005) Colloid Interface Sci., 288, p. 166
  • Tagliazucchi, M., De La Olvera, C.M., Szleifer, I., (2010) Proc. Natl. Acad. Sci. U.S.A., 107, p. 5300
  • Rupert, L.A.M., Hoekstra, D., Engberts, J.B.F.N., (1989) J. Colloid Interface Sci., 130, p. 271
  • Chen, S., Huang, K., (2000) Anal. Chem., 72, p. 2949
  • Schmidt, G., Eibl, H., Knoll, W., (1982) J. Membr. Biol., 70, p. 147
  • Knoll, W., Apell, H.-J., Eibl, H., Miller, A., (1986) Eur. Biophys. J., 13, p. 187
  • Ichas, F., Mazat, J.-P., (1998) Biochim. Biophys. Acta, 1366, p. 33
  • Hartzell, C., Putzier, I., Arreola, J., (2005) Annu. Rev. Physiol., 67, p. 719
  • Imbert, E., Souirti, A., Menard, V., Plucer, F., Josefowicz, M., Miconney, V., (1994) J. Appl. Polym. Sci., 52, p. 91
  • Nakashima, N., Taguchi, T., Takada, Y., Fujio, K., Kunitake, M., Manabe, O., (1991) J. Chem. Soc., Chem. Commun., 232
  • Greenfield, M.A., Hoffman, J.R., De La Cruz, M.O., Stupp, S.I., (2010) Langmuir, 26, p. 3641
  • Siwy, Z.S., Powell, M.R., Petrov, A., Kalman, E., Trautmann, C., Eisenberg, R.S., (2006) Nano Lett., 6, p. 1729
  • Powell, M.R., Sullivan, M., Vlassiouk, I., Constantin, D., Sudre, O., Martens, C.C., Eisenberg, R.S., Siwy, Z.S., (2008) Nat. Nanotechnol., 3, p. 51
  • Kühnle, R.I., Börner, H.G., (2011) Angew. Chem., Int. Ed., 50, p. 4499
  • Kühnle, R.I., Gebauer, D., Börner, H.G., (2011) Soft Matter, , DOI: 10.1039/c1sm05625e
  • Takehara, K., Aihara, M., Miura, Y., Tanaka, F., (1996) Bioelectrochem. Bioenerg., 39, p. 135
  • Yamauchi, Y., Suzuki, N., Kimura, T., (2009) Chem. Commun., 5689
  • Suzuki, N., Kimura, T., Yamauchi, Y., (2010) J. Mater. Chem., 10, p. 5294
  • Angelomé, P.C., Fuertes, M.C., Soler-Illia, G., (2006) J. A. A. Adv. Mater., 18, p. 2397
  • Fuertes, M.C., López-Alcaraz, F.J., Marchi, M.C., Troiani, H., Luca, V., Míguez, H., Soler-Illia, G.J.A.A., (2007) Adv. Funct. Mater., 17, p. 1247
  • Soler-Illia, G.J.A.A., Angelomé, P.C., Fuertes, M.C., Calvo, A., Wolosiuk, A., Zelcer, A., Bellino, M.G., Martínez, E.D., (2011) J. Sol-Gel Sci. Technol., 57, p. 299

Citas:

---------- APA ----------
Brunsen, A., Díaz, C., Pietrasanta, L.I., Yameen, B., Ceolín, M., Soler-Illia, G.J.A.A. & Azzaroni, O. (2012) . Proton and calcium-gated ionic mesochannels: Phosphate-bearing polymer brushes hosted in mesoporous thin films as biomimetic interfacial architectures. Langmuir, 28(7), 3583-3592.
http://dx.doi.org/10.1021/la204854r
---------- CHICAGO ----------
Brunsen, A., Díaz, C., Pietrasanta, L.I., Yameen, B., Ceolín, M., Soler-Illia, G.J.A.A., et al. "Proton and calcium-gated ionic mesochannels: Phosphate-bearing polymer brushes hosted in mesoporous thin films as biomimetic interfacial architectures" . Langmuir 28, no. 7 (2012) : 3583-3592.
http://dx.doi.org/10.1021/la204854r
---------- MLA ----------
Brunsen, A., Díaz, C., Pietrasanta, L.I., Yameen, B., Ceolín, M., Soler-Illia, G.J.A.A., et al. "Proton and calcium-gated ionic mesochannels: Phosphate-bearing polymer brushes hosted in mesoporous thin films as biomimetic interfacial architectures" . Langmuir, vol. 28, no. 7, 2012, pp. 3583-3592.
http://dx.doi.org/10.1021/la204854r
---------- VANCOUVER ----------
Brunsen, A., Díaz, C., Pietrasanta, L.I., Yameen, B., Ceolín, M., Soler-Illia, G.J.A.A., et al. Proton and calcium-gated ionic mesochannels: Phosphate-bearing polymer brushes hosted in mesoporous thin films as biomimetic interfacial architectures. Langmuir. 2012;28(7):3583-3592.
http://dx.doi.org/10.1021/la204854r