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Abstract:

We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was expressed as: baseline of the record background activity; area under the curve (AUC) of opsonized zymosan response; maximum peak (MP) response; time to MP (TMP); and total time (TT). Simultaneously, circulating immune complexes (CIC) in sera were evaluated by polyethylene glycol precipitation technique. The results demonstrated that lung cancer patients with CS III had an increase of TMP and TT values, while breast cancer patients with CS IV showed the lowest values of AUC and MP compared with the control group. The CIC levels were increased in all the cancer patients. There was no correlation between the baseline CL activity and the levels of immune complexes. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

Registro:

Documento: Artículo
Título:Chemiluminescence production by neutrophils and immune complex levels in cancer patients
Autor:Chasseing, N.A.; Barañao, R.I.; Fernández, O.; Bordenave, H.; Rumi, L.S.
Filiación:Consejo Nacional de Investigacíones Cientlficas y Técnicas de la, Repúblics Argentina, (CONICET), Argentina
Instituto de Biología y Medicina Experimental, Obligado 2490 1428, Buenos Aires, Argentina
Department of Oncology, Hospital Zonal de Agudos I. Iriarte, Quilmes, Pcia. de, Buenos Aires, Argentina
Palabras clave:endogenous compound; zymosan; antigen antibody complex; article; breast cancer; chemoluminescence; clinical article; controlled study; female; human; human cell; lung cancer; male; neutrophil; Antigen-Antibody Complex; Breast Neoplasms; Chemiluminescence; Human; Lung Neoplasms; Neutrophils; Opsonins; Oxygen; Polyethylene Glycols; Zymosan
Año:1993
Volumen:11
Número:5
Página de inicio:517
Página de fin:522
DOI: http://dx.doi.org/10.3109/07357909309011669
Título revista:Cancer Investigation
Título revista abreviado:Cancer Invest.
ISSN:07357907
CODEN:CINVD
CAS:zymosan, 58856-93-2, 68652-43-7, 9010-72-4; Antigen-Antibody Complex; Opsonins; Oxygen, 7782-44-7; Polyethylene Glycols; Zymosan, 9010-72-4
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07357907_v11_n5_p517_Chasseing

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Citas:

---------- APA ----------
Chasseing, N.A., Barañao, R.I., Fernández, O., Bordenave, H. & Rumi, L.S. (1993) . Chemiluminescence production by neutrophils and immune complex levels in cancer patients. Cancer Investigation, 11(5), 517-522.
http://dx.doi.org/10.3109/07357909309011669
---------- CHICAGO ----------
Chasseing, N.A., Barañao, R.I., Fernández, O., Bordenave, H., Rumi, L.S. "Chemiluminescence production by neutrophils and immune complex levels in cancer patients" . Cancer Investigation 11, no. 5 (1993) : 517-522.
http://dx.doi.org/10.3109/07357909309011669
---------- MLA ----------
Chasseing, N.A., Barañao, R.I., Fernández, O., Bordenave, H., Rumi, L.S. "Chemiluminescence production by neutrophils and immune complex levels in cancer patients" . Cancer Investigation, vol. 11, no. 5, 1993, pp. 517-522.
http://dx.doi.org/10.3109/07357909309011669
---------- VANCOUVER ----------
Chasseing, N.A., Barañao, R.I., Fernández, O., Bordenave, H., Rumi, L.S. Chemiluminescence production by neutrophils and immune complex levels in cancer patients. Cancer Invest. 1993;11(5):517-522.
http://dx.doi.org/10.3109/07357909309011669