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Referencias:

• Atchley, W.R., Gaskins, C.T., Anderson, D., Statistical properties of ratios. I. Empirical results (1976) Syst. Zool., 25, pp. 137-148
• Barja, G., Mitochondrial free radical production and aging in mammals and birds (1998) Ann. N. Y. Acad. Sci., 854, pp. 224-238
• Bennett, R.G., Hamel, F.G., Duckworth, W.C., Characterization of the insulin inhibition of the peptidolytic activities of the insulin-degrading enzyme-proteasome complex (1997) Diabetes, 46, pp. 197-203
• Bross, P., Corydon, T.J., Andresen, B.S., Jørgensen, M.M., Bolund, L., Gregersen, N., Protein misfolding and degradation in genetic diseases (1999) Hum. Mutat., 14, pp. 186-198
• Broughton, S., Partridge, L., Insulin/IGF-like signalling, the central nervous system and ageing (2009) Biochem. J., 15, pp. 1-12
• Buck, S., Nicholson, M., Dudas, S.P., Baker, G.T., Arking, R., Larval regulation of adult longevity in a genetically selected long lived strain of Drosophila melanogaster (1993) Heredity, 71, pp. 23-32
• Buck, S., Wells, R.A., Dudas, S.P., Baker, G.T., Arking, R., Chromosomal localization and regulation of the longevity determinant genes in a selected strain of Drosophila melanogaster (1993) Heredity, 71, pp. 11-22
• Butov, A., Johnson, T.E., Cypser, J., Sannikov, I., Volkov, M., Sehl, M., Yashin, A.I., Hormesis and debilitation effects in stress experiments using the nematode worm Caenorhabditis elegans: the model of balance between cell damage and HSP level (2001) Exp. Gerontol., 37, pp. 57-66
• Calabrese, E.J., Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework (2007) Toxicol. Appl. Pharmacol., 222, pp. 122-128
• Clancy, D.J., Gems, D., Harshman, L.G., Oldham, S., Stocker, H., Hafen, E., Leevers, S.J., Partridge, L., Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein (2001) Science, 292, pp. 104-106
• Curtsinger, J.W., Khazaeli, A.A., Life span, QTLs, age-specificity and pleiotropy in Drosophila (2002) Mech. Ageing Dev., 123, pp. 81-93
• Cypser, J.R., Johnson, T.E., Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity (2002) J. Gerontol. Biol. Sci., 57 A, pp. B109-B114
• Cypser, J.R., Johnson, T.E., Hormesis in Caenorhabditis elagans dauer-defective mutants (2003) Biogerontology, 4, pp. 203-214
• Duckworth, W.C., Bennett, R.G., Hamel, F.G., A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic protein-ase (1994) J. Biol. Chem., 269, pp. 24575-24580
• Dupuis, J., Siegmund, D., Statistical methods for mapping quantitative trait loci from a dense set of markers (1999) Genetics, 151, pp. 373-386
• FlyBase Consortium The FlyBase database of the Drosophila genome projects and community literature (2003) Nucleic Acids, 31, pp. 172-175. , http://flybase.org
• Garcia, J.V., Fenton, B.W., Rosner, M.R., Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster (1988) Biochemistry, 27, pp. 4237-4244
• Gething, M.J., Sambrook, J., Protein folding in the cell (1992) Nature, 355, pp. 33-45
• Gomez, F.H., Bertoli, C.I., Sambucetti, P., Scannapieco, A.C., Norry, F.M., Heat-induced hormesis in longevity as correlated response to thermal-stress selection in Drosophila buzzatii (2009) J. Therm. Biol., 34, pp. 17-22
• Goto, S.G., Expression of Drosophila homologue of senescence marker protein-30 during 674 cold acclimation (2000) J. Insect Physiol., 46, pp. 1111-1120
• Gregersen, N., Bolund, L., Bross, P., Protein misfolding, aggregation and degradation in disease (2003) Methods. Mol. Biol., 232, pp. 3-16
• Harman, D., Aging: a theory based on free radical and tion chemistry (1956) J. Gerontol., 11, pp. 298-300
• Hercus, M.J., Loeschcke, V., Rattan, S.I.S., Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress (2003) Biogerontology, 4, pp. 149-156
• Jiang, C., Zeng, Z.-B., Multiple trait analysis of genetic mapping for quantitative trait loci (1995) Genetics, 140, pp. 1111-1127
• Jolly, C., Usson, Y., Morimoto, R.I., Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules (heat shock green fluorescent protein dynamics nuclear organization nuclear structures) (1999) Proc. Natl. Acad. Sci. U. S. A., 96, pp. 6769-6774
• Katewa, S.D., Kapahi, P., Role of TOR signaling in aging and related biological processes in Drosophila melanogaster (2011) Exp. Gerontol., 46, pp. 382-390
• Kenyon, C., A conserved regulatory system for aging (2001) Cell, 105, pp. 165-168
• Kenyon, C., The plasticity of aging: insights from long-lived mutants (2005) Cell, 120, pp. 449-460
• Khazaeli, A.A., Tatar, M., Pletcher, S.D., Curtsinger, J.W., Heat-induced longevity extension in Drosophila. 1. Heat treatment, mortality, and thermotolerance (1997) J. Gerontol. A. Biol. Sci. Med. Sci., 52, pp. B48-B52
• Kline, M.P., Morimoto, R.I., Repression of the heat-shock factor-1 transcriptional activation domain is modulated by constitutive phosphorylation (1997) Mol. Cell. Biol., L7, pp. 2107-2115
• Ku, H.H., Brunk, U.T., Sohal, R.S., Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species (1993) Free Radic. Biol. Med., 15, pp. 621-627
• Lai, C., Parnell, L.D., Lyman, R.F., Ordovas, J.M., Mackay, T.F.C., Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping (2006) Mech. Ageing Dev., 128, pp. 237-249
• Le Bourg, E., Minois, N., Bullens, P., Baret, P., A mild stress due to hypergravity exposure at young age increases longevity in Drosophila melanogaster males (2000) Biogerontology, 1, pp. 145-155
• Le Bourg, E., Valenti, P., Lucchetta, P., Payre, F., Effects of mild heat shocks at young age and longevity in Drosophila melanogaster (2001) Biogerontology, 2, pp. 155-164
• Lee, K.P., Simpson, S.J., Clissold, F.J., Brooks, R., Ballard, J.W.O., Taylor, P.W., Soran, N., Raubenheimer, D., Lifespan and reproduction in Drosophila: new insights from nutritional geometry (2008) Proc. Natl. Acad. Sci. U. S. A., 105, pp. 2498-2503
• Leips, J., Mackay, T.F.C., Quantitative trait loci for life span in Drosophila melanogaster: interactions with genetic background and larval density (2000) Genetics, 155, pp. 1773-1788
• Leips, J., Mackay, T.F.C., The complex genetic architecture of Drosophila life span (2002) Exp. Aging Res., 28, pp. 361-390
• Lin, Y.-J., Seroude, L., Benzer, S., Extended life-span and stress resistance in the Drosophila mutant methuselah (1998) Science, 282, pp. 943-946
• Lindquist, S., Regulation of protein-synthesis during heat-shock (1981) Nature, 293, pp. 311-314
• Lis, J.T., Mason, P., Peng, J., Price, D.H., Werner, J., P-TEFb kinase recruitment and function at heat shock loci (2000) Genes Dev., 14, pp. 792-803
• Lithgow, G.J., White, T.M., Melov, S., Johnson, T.E., Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal-stress (1995) Proc. Natl. Acad. Sci. U. S. A., 92, pp. 7540-7544
• Mandavilli, B.S., Santos, J.H., Van Houten, B., Mitochondrial DNA repair and aging (2002) Mutat. Res., 509, pp. 127-151
• McColl, G., Hoffmann, A.A., McKechnie, S.W., Response of two heat shock genes to selection for knockdown heat resistance in Drosophila melanogaster (1996) Genetics, 143, pp. 1615-1627
• Miwa, S., Riyahi, K., Partridge, L., Brand, M.D., Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila (2006) Ann. N. Y. Acad. Sci., 1019, pp. 388-391
• Morgan, T.J., Mackay, T.F.C., Quantitative trait loci for thermotolerance phenotypes in Drosophila melanogaster (2006) Heredity, 96, pp. 232-242
• Norry, F.M., Loeschcke, V., Heat-induced expression of a molecular chaperone decreases by selecting for long-lived individuals (2003) Exp. Gerontol., 38, pp. 673-681
• Norry, F.M., Dahlgaard, J., Loeschcke, V., Quantitative trait loci affecting knockdown resistance to high temperature in Drosophila melanogaster (2004) Mol. Ecol., 13, pp. 3585-3594
• Norry, F.M., Scannapieco, A.C., Sambucetti, P., Bertoli, C., Loeschcke, V., QTL for the thermotolerance effect of heat hardening, knockdown resistance to heat and chill-coma recovery in an intercontinental set of recombinant inbred lines of Drosophila melanogaster (2008) Mol. Ecol., 17, pp. 4570-4581
• Nuzhdin, S.V., Pasyukova, E.G., Dilda, C.L., Zeng, Z.B., Mackay, T.F.C., Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster (1997) Proc. Natl. Acad. Sci. U. S. A., 94, pp. 9734-9739
• Nuzhdin, S.V., Khazaeli, A.A., Curtsinger, J.W., Survival analysis of life span quantitative trait loci in Drosophila melanogaster (2005) Genetics, 170, pp. 718-731
• Olsen, A., Vantipalli, M.C., Lithgow, G.J., Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments (2006) Biogerontology, 7, pp. 221-230
• Parsell, D.A., Lindquist, S., The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins (1993) Annu. Rev. Genet., 27, pp. 437-496
• Parsons, P.A., Aging: the fitness-stress continuum and genetic variability (2002) Exp. Aging Res., 28, pp. 347-359
• Partridge, L., Gems, D., Withers, D.J., Sex and death: what is the connection? (2005) Cell, 120, pp. 461-472
• Rea, S.L., Wu, D., Cypser, J.R., Vaupel, J.W., Johnson, T.E., A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans (2005) Nat. Genet., 37, pp. 894-898
• Reiwitch, S.G., Nuzhdin, S.V., Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes (2002) Genetics, 80, pp. 1-6
• Sarup, P., Loeschcke, V., Life extension and the position of the hormetic zone depends on sex and genetic background in Drosophila melanogaster (2010) Biogerontology, 12, pp. 109-117
• Scannapieco, A.C., Sørensen, J.G., Loeschcke, V., Norry, F.M., Heat-induced hormesis in longevity of two sibling Drosophila species (2007) Biogerontology, 8, pp. 315-325
• Simon, A.F., Shih, C., Mack, A., Benzer, S., Steroid control of longevity in Drosophila melanogaster (2003) Science, 299, pp. 1407-1410
• Simonsen, A., Cumming, R.C., Lindmo, K., Galaviz, V., Cheng, S., Rusten, T.E., Finley, K.D., Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles (2007) Genetics, 176, pp. 1283-1297
• Sohal, R.S., Arnold, L.A., Sohal, B.H., Age-related changes in antioxidant enzymes and prooxidant generation in tissues of the rat with special reference to parameters in two insect species (1990) Free Radic. Biol. Med., 9, pp. 495-500
• Sørensen, J.G., Kristensen, T.N., Loeschcke, V., The evolutionary and ecological role of heat shock proteins (2003) Ecol. Lett., 6, pp. 1025-1037
• Sørensen, J.G., Nielsen, M.M., Loeschcke, V., Gene expression profile analysis of Drosophila melanogaster selected for resistance to environmental stressors (2007) J. Evol. Biol., 20, pp. 1624-1636
• Sun, J., Folk, D., Bradley, T.J., Tower, J., Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster (2002) Genetics, 161, pp. 661-672
• Tatar, M., Kopelman, A., Epstein, D., Tu, M.P., Yin, C.M., Garofalo, R.S., A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function (2001) Science, 292, pp. 107-110
• Tissenbaum, H.A., Ruvkun, G., An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans (1998) Genetics, 148, pp. 703-717
• Tower, J., Hsp and aging (2009) Trends Endocrinol. Metab., 20, pp. 216-222
• Tower, J., Heat shock proteins and Drosophila aging (2011) Exp. Gerontol., 46, pp. 355-362
• Vermeulen, C.J., Loeschcke, V., Longevity and the stress response in Drosophila (2007) Exp. Gerontol., 42, pp. 153-159
• Vermeulen, C.J., Bijlsma, R., Loeschcke, V., A major QTL affects temperature sensitive adult lethality and inbreeding depression in life span in Drosophila melanogaster (2008) BMC Evol. Biol., 8. , 1-1
• Vieira, C., Pasyukova, E.G., Zeng, Z.B., Hackett, J.B., Lyman, R.F., Mackay, T.F.C., Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster (2000) Genetics, 154, pp. 213-227
• Wallace, D.C., Melov, S., Radicals r'aging (1998) Nat. Genet., 19, pp. 105-106
• Wang, M.H., Lazebny, O., Harshman, L.G., Nuzhdin, S.V., Environment-dependent survival of Drosophila melanogaster: a quantitative genetic analysis (2004) Aging Cell, 3, pp. 133-140
• Wang, S.C., Basten, J., Zeng, Z.-B., (2010) Windows QTL Cartographer 2.5. Department of Statistics, , North Carolina State University, Raleigh, NC
• Wolfe, S.L., (1995) Introduction to Cell and Molecular Biology, , Hadsworth Publishing Company, Belmont, CA
• Yashin, A.I., Cypser, J.R., Johnson, T.E., Michalski, A.I., Boyko, S.I., Novoseltsev, V.N., Ageing and survival after different doses of heat shock: the results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans (2001) Mech. Ageing Dev., 122, pp. 1477-1495
• Zeng, Z.-B., Precision mapping of quantitative trait loci (1994) Genetics, 136, pp. 1457-1468

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