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Damonte, E.B.; García, C.C. "Perspectives for the Therapy against Arenavirus Infections" (2005) Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats:115-138
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Abstract:

Five arenaviruses are able to cause severe hemorrhagic fevers (HF) in humans, and two of them, Lassa virus and Junin virus generate periodic annual outbreaks of severe hemorrhagic fever with high mortality rate in West Africa and Argentina, respectively. This chapter describes the drawbacks of the present treatment of arenavirus HF, mainly based on the administration of immune plasma or the drug ribavirin, and the future perspectives for therapy, mainly focused on new possible targets in early and late stages of the replicative cycle, responsible of viral entry to the cell and virus maturation, assembly and budding, respectively. © 2005 John Wiley & Sons, Inc.

Registro:

Documento: Parte de libro
Título:Perspectives for the Therapy against Arenavirus Infections
Autor:Damonte, E.B.; García, C.C.
Filiación:Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina
Palabras clave:Antiviral therapy; Arenavirus; Assembly; Budding; Hemorrhagic fever; Junin Virus; Lassa Virus; Replicative cycle; Virus entry; Virus maturation
Año:2005
Página de inicio:115
Página de fin:138
DOI: http://dx.doi.org/10.1002/0471716715.ch5
Título revista:Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats
Título revista abreviado:Antiviral Drug Discov. for Emerging Dis. and Bioterrorism Threat.
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_04716682_v_n_p115_Damonte

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Citas:

---------- APA ----------
Damonte, E.B. & García, C.C. (2005) . Perspectives for the Therapy against Arenavirus Infections. Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats, 115-138.
http://dx.doi.org/10.1002/0471716715.ch5
---------- CHICAGO ----------
Damonte, E.B., García, C.C. "Perspectives for the Therapy against Arenavirus Infections" . Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats (2005) : 115-138.
http://dx.doi.org/10.1002/0471716715.ch5
---------- MLA ----------
Damonte, E.B., García, C.C. "Perspectives for the Therapy against Arenavirus Infections" . Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats, 2005, pp. 115-138.
http://dx.doi.org/10.1002/0471716715.ch5
---------- VANCOUVER ----------
Damonte, E.B., García, C.C. Perspectives for the Therapy against Arenavirus Infections. Antiviral Drug Discov. for Emerging Dis. and Bioterrorism Threat. 2005:115-138.
http://dx.doi.org/10.1002/0471716715.ch5