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Abstract:

The effect of the water extract of Melia azedarach L. (Meliaceae) leaves on human complement and polymorphonuclear leukocytes was investigated. This extract showed a strong anticomplementary activity, which was more pronounced in the classical pathway assay. The extract did not affect the phagocytic activity of polymorphonuclear leukocytes, nor the respiratory burst of these cells as measured by the nitro blue tetrazolium reduction assay. © 1994.

Registro:

Documento: Artículo
Título:Effect of Melia azedarach L. leaf extracts on human complement and polymorphonuclear leukocytes
Autor:Benencia, F.; Courrèges, M.C.; Massouh, E.J.; Coulombié, F.C.
Filiación:Laboratory of Virology, University of Buenos Aires, 1428 Buenos Aires, Argentina
Laboratory of Immunochemistry. Quimica Biologica, Pabellón II, Piso 4, Facultad de Ciencias Exactas Naturales, University of Buenos Aires, 1428 Buenos Aires, Argentina
Palabras clave:Antiinflammatory effect; Complement; Leaf extracts; Melia azedarach L.; Polymorphonuclear leukocytes; complement; nitroblue tetrazolium; plant extract; antiinflammatory activity; article; complement activation; complement alternative pathway; complement inhibition; controlled study; human; human cell; neutrophil; normal human; phagocytosis; plant leaf; respiratory burst; Cells, Cultured; Complement Pathway, Alternative; Complement Pathway, Classical; Human; Neutrophils; Phagocytosis; Plant Extracts; Support, Non-U.S. Gov't
Año:1994
Volumen:41
Número:1-2
Página de inicio:53
Página de fin:57
DOI: http://dx.doi.org/10.1016/0378-8741(94)90057-4
Título revista:Journal of Ethnopharmacology
Título revista abreviado:J. Ethnopharmacol.
ISSN:03788741
CODEN:JOETD
CAS:Plant Extracts
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03788741_v41_n1-2_p53_Benencia

Referencias:

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  • Andrei, Coulombié, Courrèges, de Torres, Coto, Meliacine, an antiviral compound from Melia azedarach L., inhibits interferon production (1990) Journal of Interferon Research, 10, pp. 469-475
  • Bhakuni, Dhar, Dhar, Dhawan, Mehrotra, Screening of plants for biological activity. Part II (1969) Indian Journal of Experimental Biology, 7, pp. 250-262
  • Bray, Warhust, Conolly, O'Neill, Phillipson, Plants as sources of antimalarial drugs. Part 7. Activity of some species of Meliaceae plants and their constituent limonoids (1990) Phytotherapy Research, 4, pp. 29-34
  • Coulombié, Andrei, Laguens, de Torres, Coto, Partially purified leaf extracts of Melia azedarach L. inhibit Tacaribe virus growth in neo-natal mice (1992) Phytotherapy Research, 6, pp. 15-19
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  • Wachsman, Damonte, Goto, de Torres, Antiviral effects of Melia azedarach L. leaves extracts on Sindbis virus-infected cells (1987) Antiviral Research, 8, pp. 1-12
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Citas:

---------- APA ----------
Benencia, F., Courrèges, M.C., Massouh, E.J. & Coulombié, F.C. (1994) . Effect of Melia azedarach L. leaf extracts on human complement and polymorphonuclear leukocytes. Journal of Ethnopharmacology, 41(1-2), 53-57.
http://dx.doi.org/10.1016/0378-8741(94)90057-4
---------- CHICAGO ----------
Benencia, F., Courrèges, M.C., Massouh, E.J., Coulombié, F.C. "Effect of Melia azedarach L. leaf extracts on human complement and polymorphonuclear leukocytes" . Journal of Ethnopharmacology 41, no. 1-2 (1994) : 53-57.
http://dx.doi.org/10.1016/0378-8741(94)90057-4
---------- MLA ----------
Benencia, F., Courrèges, M.C., Massouh, E.J., Coulombié, F.C. "Effect of Melia azedarach L. leaf extracts on human complement and polymorphonuclear leukocytes" . Journal of Ethnopharmacology, vol. 41, no. 1-2, 1994, pp. 53-57.
http://dx.doi.org/10.1016/0378-8741(94)90057-4
---------- VANCOUVER ----------
Benencia, F., Courrèges, M.C., Massouh, E.J., Coulombié, F.C. Effect of Melia azedarach L. leaf extracts on human complement and polymorphonuclear leukocytes. J. Ethnopharmacol. 1994;41(1-2):53-57.
http://dx.doi.org/10.1016/0378-8741(94)90057-4